https://www.ourmbclife.org/episodes daily 0.75 2026-04-02 https://www.ourmbclife.org/episodes/sabcs-2025 monthly 0.5 2026-03-11 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/92262db8-65a3-4d75-87d6-1e122287512d/tempImageif0rtx.jpg Episodes - Report Back From SABCS 2025: Key Clinical Trial Updates in MBC - Bora Lim, MD Dr. Lim is a renowned clinical-translational investigator specializing in oncology, with a deep-rooted commitment to addressing the challenges of metastatic and inflammatory breast cancer. Dr. Lim is highly invested in clinical and research efforts to understand ‘difficult-to-treat’ cancers like IBC, treatment refractory triple negative breast cancers and other rare breast cancers by organizing team science and adopting/ applying cutting edge technologies matching with effective, novel therapeutics. A notable recent breakthrough from her studies is the role of non-coding RNA in breast cancer, inflammatory breast cancer TME, single cell genomic and transcriptomic analysis of normal and advanced breast cancer tissues, novel blood biomarker and development of such biomarker -integrated clinical trials. She is currently serving as a translational lead for both Breast Medical Oncology department and Morgan Welch IBC Research and Clinic program at the UT MD Anderson Cancer Center. https://www.ourmbclife.org/episodes/health-insurance-changes-and-bc-community monthly 0.5 2026-01-09 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/3c13e481-e200-4712-9a0b-80af32f2b6cd/Monica+Bryant+1.jpg Episodes - Health Insurance Changes and the Breast Cancer Community - Monica Fawzy Bryant, Esq Monica is a cancer rights attorney, speaker, and author, dedicated to improving access to and availability of quality information on cancer survivorship issues. She is the co-founder and Chief Operating Officer for Triage Cancer, a national, nonprofit organization that provides education on the practical and legal issues that may impact individuals diagnosed with cancer and their caregivers, through events, materials, and resources. Throughout her career, Monica has provided over one thousand educational seminars, written articles, blogs, appeared on radio and television shows, and co-authored a book published by the American Bar Association called Cancer Rights Law: An Interdisciplinary Approach. Monica is an Adjunct Law Professor at University of Illinois at Chicago School of Law, teaching a class on Cancer Rights. You can connect with Triage Cancer on all social media channels @TriageCancer or their LinkedIn You can connect with Monica on Twitter @NavSurvivorship and on LinkedIn. https://www.ourmbclife.org/episodes/best-life-with-palliative-care monthly 0.5 2025-11-19 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/14769ecf-2316-4bb0-911e-75c0303e113f/Jones+headshot+2024+white+coat.jpeg Episodes - Living Your Best Life with Palliative Care - Christopher Allen Jones, MD, MBA, CPC, HMDC, FAAHPM Dr. Jones supports “everyone's Plan A of getting better and back to normal life and Plan B if things don't go as we hope". Helping someone become well enough to take a trip to the beach or the mountains or play a bit more with their kids or grandkids is what makes me tick!” Dr. Jones started his health care career during college as a nursing assistant in a nursing home in Pennsylvania. During his training at Brown University, Dr. Jones came to discover that his true passion was caring for people with serious illness. He spent the first decade of his career in hospitals, providing palliative services to patients admitted to the floors or intensive care units. Since then, missing longer-term relationships with patients, Dr. Jones has spent more time on the outpatient side of palliative care, working to partner with those with serious or advanced illnesses to help make life better. Whether treating pain, constipation, nausea, shortness of breath, anxiety, depression, fatigue, poor appetite, poor sleep, or any other symptoms making people feel lousy, he aims to use medicines and non-medicine strategies to improve quality of life and function. Dr. Jones is currently the Director of Outpatient Palliative Care and the Clinical Vice Chief of Palliative Care for Duke University Health System. Follow Dr. Jones on Twitter @CAJonesMD https://www.ourmbclife.org/episodes/we-remember-2025 monthly 0.5 2025-10-29 https://www.ourmbclife.org/episodes/asco-2025 monthly 0.5 2025-10-27 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/68187872-d8b4-407a-896d-76603432d2bf/Dr.+Ashley+Schreier+headshot.jpg Episodes - ASCO 2025: What’s New for MBC? - Dr. Ashley Schreier Dr. Schreier is an Assistant Professor of Medicine within the Division of Hematology and Medical Oncology at Weill Cornell Medicine. She treats patients with all forms of breast cancer and has a special interest in caring for those with triple negative breast cancer (TNBC), which has been the emphasis of her research. Dr. Schreier received her B.S. in 2012 from Cornell University. She then entered medical school at NYIT College of Osteopathic Medicine followed by residency in Internal Medicine at the Albert Einstein College of Medicine/Montefiore Medical Center and fellowship in Hematology and medical Oncology at Weill Cornell. She has been an attending here since 2023 and works as a clinician in breast medical oncology and is also an active clinical and translational investigator. https://www.ourmbclife.org/episodes/how-a-death-doula-can-help monthly 0.5 2025-10-02 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/66407839-a687-436a-802d-0811a771d502/Death+Doula+Deltra+Headshots.png Episodes - Facing Fears & Living Fiercely: How a Death Doula Can Help - Deltra James Deltra is a New England–based mother, poet, and patient advocate. After being diagnosed at age 33 with triple-negative breast cancer that had already spread to her liver, she sought community through story sharing and creativity; creating a social media space, The Beatnik Boob, for cancer patients and caregivers to share wins and woes through poetry and art. Beginning as a member of the For the Breast of Us inaugural class of Baddie Ambassadors, she found her footing in the advocacy and cancer communities. Since then, she has joined forces with organizations—such as TOUCH, The Black Breast Cancer Alliance (BBCA); Project Life; Bright Spot Network; and Cactus Cancer Society—to support others in connecting with resources that aid in areas she is passionate about: mental wellness, therapeutic creative expression, parenting, divorce after diagnosis, and disparities due to income and race. Deltra has lent her voice and experience on panels for organizations, such as Infinite Strength and SHARE as well as on various podcasts, including Empowered Intimacy which she co-hosts. After taking notice of rampant death anxiety within the cancer community, she ventured into deathcare work adding death doula to her patient advocacy repertoire as she assists fellow patients in accomplishing necessary end-of-life planning while addressing fear. More about Deltra: Navigating End-of-Life Priorities with Courage and Care (Compassion and Choices, 2025) Living Life to the Fullest Despite a Terminal Diagnosis (Bezzy BC, 2021) Ways to connect with her: IG - @deltra_does_it email - deltratjames@gmail.com https://www.ourmbclife.org/episodes/metavivor-driving-force monthly 0.5 2025-06-16 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/f32cec9f-b000-4963-8828-57efa78c700d/Kelly+Shanahan+1.jpeg Episodes - METAvivor: A Driving Force in Research, Advocacy, & Hope - Kelly Shanahan, M.D. In 2008, Dr. Kelly Shanahan had everything going for her: a busy and successful ob-gyn practice; a precocious 9 year old daughter; and a well used passport from traveling all over the world with her family to attend conferences, with a liberal dose of vacation on the side. When she was diagnosed with stage IIB breast cancer, she considered it a mere bump in the road. And for five years, breast cancer was an aside, something to put in the past medical history section of forms. Even when she developed sudden back pain, Kelly never thought it could be breast cancer rearing its ugly head – a pulled muscle, a herniated disc maybe, but not what it turned out to be: metastatic breast cancer in virtually every bone in her body, with a fractured vertebrae and an about to break left femur. Kelly was diagnosed in 2013, on her 53rd birthday. Neuropathy from the chemo cost her her career, but she has found a new purpose in advocacy. Kelly is the current president of METAvivor, a member of the Metastatic Breast Cancer Alliance, a Komen Advocate in Science, on the symptom intervention committee of the Alliance for Clinical Trials in Oncology, a grant reviewer and research advocate. She is passionate about getting patients to the table in the design, implementation, and follow up of clinical trials. Follow her on Twitter @stage4kelly. Kelly Shanahan is a mother, a wife, a daughter, a doctor, a woman LIVING with metastatic breast cancer. https://www.ourmbclife.org/episodes/dosing-done-right-pcdi monthly 0.5 2025-05-07 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/97a1b82b-d895-41e4-a54f-d4ee91e25f54/PCDI+2025.png Episodes - Dosing Done Right: The PCDI Survey & Why It Matters - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/2eb52c85-fe18-4efe-8db5-15444ab441c5/JM+headshot3.png Episodes - Dosing Done Right: The PCDI Survey & Why It Matters - Julia Maues Julia Maués’ life took an unexpected turn when she was diagnosed with breast cancer while pregnant in 2013. After delivering a healthy baby boy, she soon learned the cancer had spread to her bones, liver, and brain. Now living with metastatic breast cancer for nearly 12 years, she has personally benefited from treatment advances driven by research and clinical trials—fueling her commitment to bringing patients’ voices into research to ensure it is inclusive, patient-centered, and reflective of real-world experiences. Julia co-founded GRASP (Guiding Researchers & Advocates to Scientific Partnerships), a nonprofit that bridges the gap between patients and researchers to make cancer research more impactful and accessible. She also leads the Patient-Centered Dosing Initiative (PCDI), advocating for treatment strategies that optimize both efficacy and tolerability to improve patient outcomes. Her advocacy spans multiple organizations, including the San Antonio Breast Cancer Symposium Planning Committee, BIG Against Breast Cancer, ASCO, the Metastatic Breast Cancer Alliance, and the DoD CDMRP. She has spoken at conferences across the U.S. and internationally and has helped shape policy and research initiatives through strategic influence. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/b02ddad4-9284-4e4c-a6de-4889c30a0a0a/Stephanie+Walker.jpg Episodes - Dosing Done Right: The PCDI Survey & Why It Matters - Stephanie Walker Living with De Novo metastatic breast cancer since July 2015, Stephanie is a retired RN with close to 40 years experience in pediatric and adult critical care, as well as emergency department experience in critical access size hospitals to Level 1 trauma centers. Her last 14 years in nursing was spent in hospice/end of life care. After being diagnosed with MBC in 2018, Stephanie began to volunteer with many different breast cancer organizations. She is the 2025 Vice Chair of the Metastatic Breast Cancer Alliance and the project lead of the BECOME (Black Experience of Clinical Trials and Opportunities for Meaningful Engagement) initiative. She was also instrumental in the planning and participation in the Black Wo(men) Speak Symposium held in conjunction with SABCS 2022. She is also a Living Beyond Breast Cancer Hear My Voice graduate, as well as a helpline volunteer. She is also a Project Lead grad of 2022. She is the Co-Chair of the working group that focuses on removing barriers to standard of care and quality of life. Stephanie will answer any questions, even the hard ones regarding her own mental health. She isn’t defined by her cancer and wants others to be their own light to shine bright. She is married with adult children & grandchildren, and lives with husband John and rescue dog Rex in eastern North Carolina. https://www.ourmbclife.org/episodes/josh-newby-trf monthly 0.5 2025-04-14 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/952ecba8-8d85-45c8-94ed-ebb7531564c7/jnewby.jpeg Episodes - Trailblazers: Josh Newby & Theresa’s Research Foundation - Josh Newby Josh is currently an active trained advocate for breast cancer research. Co-founder of Theresa’s Research Foundation (501(c )3 Non-Profit ) with his mother Theresa Newby Harpole. Both his mother and himself are carriers of BRCA II. Sadly Josh’s mother passed away in 2013. The foundation continues on with her vision to accelerate breakthroughs in cancer research, and drive progress toward curative approaches for metastatic breast cancer. The Foundation hosted an annual research conference for metastatic breast cancer for 10 years, initially partnering with prestigious academic institutions such as Baylor College of Medicine, The Johns Hopkins University School of Medicine and Mayo Clinic. The Foundation has prioritized fostering meaningful interactions between cancer researchers and patient advocates. In addition to Josh’s advocacy work, he has served in various administrative roles at the Lester and Sue Smith Breast Center at Baylor College of Medicine for over 10 years. His focus has been on connecting researchers with the community, fostering collaboration, and translating research advancements into actionable outcomes. These experiences have profoundly shaped Josh’s commitment to improving the lives of all those impacted by breast cancer. https://www.ourmbclife.org/episodes/sabcs-2024 monthly 0.5 2025-03-12 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/fd442390-bd08-44db-9153-f5ca6f60a9d4/Dr+Debu+Tripathy.jpg Episodes - Report Back From SABCS 2024: What’s the Latest in MBC - Debu Tripathy, MD Dr. Tripathy is Professor of Medicine and Chair, Department of Breast Medical Oncology at the University of Texas MD Anderson Cancer Center. He received a degree in Chemical Engineering from the Massachusetts Institute of Technology and completed medical school and an internal medicine residency at Duke University followed by a Hematology/Oncology fellowship at the University of California at San Francisco. His clinical research focuses on the evaluation and development of novel therapeutics in breast cancer, specifically, those targeting sensitivity and resistance mechanisms to growth factors endocrine modulators and cell cycle control pathways as well as biomarkers that predict sensitivity and resistance. He has led clinical trials that have supported the approval of new biological therapies for breast cancer that target the HER2 oncogene and cyclin-dependent kinases, both of which have improved patient survival. Dr. Tripathy has published numerous original translational and landmark clinical research articles in the area of breast cancer and serves on several editorial boards, study sections, and societies as well as Editor-in-Chief of CURE Magazine. He has previously served as President of the American Society of Breast Disease and of the Society of Integrative Oncology. https://www.ourmbclife.org/episodes/chronic-and-cured monthly 0.5 2025-02-21 https://www.ourmbclife.org/episodes/peppbc monthly 0.5 2025-02-10 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/742f73b6-4732-4165-b510-1cd7c2b64148/Virginia+Borges+1.jpg Episodes - The Project to End Post Partum Breast Cancer - Virginia Borges, Ph.D. Dr. Borges is a Professor of Medicine with Tenure at the University of Colorado Denver and holds the Robert C. and Patricia Young-Connor endowed Chair in Young Women’s Breast Cancer. Dr. Borges is the Deputy-Head of the Division of Medical Oncology, the Director of the Breast Cancer Research Program and the Director for the Young Women’s Breast Cancer Translational Program. Dr. Borges focuses on research in Young Women’s breast cancer, the interaction of breast cancer and pregnancy and the development of novel drugs for breast cancer. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/990dea86-22fd-4130-a62e-ed8b9cde0d81/Dr.+Pepper+Schedin.png Episodes - The Project to End Post Partum Breast Cancer - Pepper J Schedin, Ph.D. Dr. Schedin is Professor of Cell, Developmental and Cancer Biology, and the Leonard Schnitzer Chair in Breast Cancer, at Oregon Health & Science University (OHSU). Dr. Schedin’s research is focused on understanding the biology behind the high rates of metastasis observed in young women with breast cancer (YOBC). Her research has led to the recognition of postpartum breast cancer (PPBC) as a new subtype of highly metastatic disease. Current research efforts are focused on the prevention and improved treatment of PPBC. Dr. Schedin is founder and co-director of the Early Career Advancement Program for OHSU Research Faculty, as well as founding member of the OHSU CIMER Mentoring Academy for Graduate Faculty. As co-director for the Cancer Prevention and Control Program, Dr. Schedin facilitated the transition leading to Comprehensive Cancer Center status for the Knight Cancer Institute. Prior to joining OHSU in 2014, Dr. Schedin was Professor in the Division of Medical Oncology at the University of Colorado Anschutz, where she co-founded the Young Women’s Breast Cancer Translational Program with Dr. Virginia Borges, a first-of-its-kind program combining a YOBC clinic with translational research. Originally trained as a molecular developmental biologist at the University of Colorado Boulder, followed by training in dietary breast cancer prevention at the AMC Cancer Research Institute in Denver, Colorado, Dr. Schedin collaborates widely with epidemiologists, oncologists, endocrinologists, chemists, immunologists, and tumor microenvironment to advance our understanding of YOBC. https://www.ourmbclife.org/episodes/tumor-microenvironment-dr-beumer monthly 0.5 2025-02-10 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/6aebe49b-8761-4ca7-83db-8a53e29bc599/Amy+Bruemer+1.jpeg Episodes - MBC 101: Tumor Microenvironment with Dr. Amy Beumer - Amy Beumer, PhD Dr. Beumer was diagnosed with Stage I breast cancer in 2017 and metastatic breast cancer in 2020. In her previous life she was a biology professor teaching various microbiology and introductory biology courses as well as conducting research in drinking water microbiology and team learning. Currently, she is upping her knowledge of cancer research, advocating, and getting as much traveling, hiking, reading, gardening and time with friends and family in as possible. Her current advocacy focuses on peer support and mentoring as well as research advocacy. https://www.ourmbclife.org/episodes/we-remember-2024 monthly 0.5 2025-10-22 https://www.ourmbclife.org/episodes/protecting-our-loved-ones-at-risk monthly 0.5 2025-02-10 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1727892950419-YQ36M5J0ZZD6SRW27LI0/BC+Screening+Page+1.jpg Episodes - Protecting Our Loved Ones at Risk - BC Screening Page 1.jpg https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1727892957644-1FRLTUJ3T0R35U8WAGFB/BC+Screening+Page+2.jpg Episodes - Protecting Our Loved Ones at Risk - BC Screening Page 2.jpg https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/09920da0-9c5a-4585-92d7-3c9840e9d4b6/Sagar+Saredesai.PNG Episodes - Protecting Our Loved Ones at Risk - Sagar Sardesai, MD Dr. Sardesai is an Associate Professor in the Division of Medical Oncology and the Medical Director of the High-Risk Breast Program at the Ohio State University Comprehensive Cancer Center with a long-standing clinical practice dedicated exclusively to caring for patients with breast cancer and those at high-risk of developing breast cancer. Dr Sardesai’s research focuses on early phase clinical trials in breast cancer prevention and survivorship. He is the vice-chair for the NCCN Breast Cancer Risk Reduction Guidelines and has authored or co-authored over 40 papers or book chapters in prestigious journals such as the New England Journal of Medicine, Journal of Clinical Oncology, Annals of Oncology and Clinical Cancer Research. In addition, he serves as Associate Editor for Cancer Medicine and on the editorial board member for Frontiers in Oncology. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/04119508-da19-40f8-bd2a-dddceb702079/headshot.jpg Episodes - Protecting Our Loved Ones at Risk - Lu Adami Lu is a Boston-based artist whose work in craft explores the possibilities of retelling the past and living to imagine a better future. They are pursuing an MFA in Visual Arts at the School of the Museum of Fine Art at Tufts University. Prior to entering graduate school, Adami worked as an educator at Milton Academy in Milton, Massachusetts, allowing them to explore the ways caring and culturally responsive pedagogy can impact a student’s experience in the visual arts classroom. Adami makes artistic work that embodies those practices while pushing forward into new areas through topic, material, and method. Their work can be found at luadami.com and on Instagram @tendermaking. https://www.ourmbclife.org/episodes/biosimilars-and-their-use-in-cancer-treatment monthly 0.5 2025-02-10 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/27a92dea-c079-4296-a4cb-7bebdaad7bef/Dr.+Julie+Gralow.jpg Episodes - Biosimilars and Their Use in Cancer Treatment - Julie Gralow, MD, FACP, FASCO|ASCO Dr. Gralow is the Chief Medical Office and Executive Vice President of American Society of Clinical Oncologists (ASCO). She is a breast medical oncologist and Professor (emeritus) of Medical Oncology and adjunct Professor of Global Health at the University of Washington School of Medicine. Dr. Gralow is the former Executive Officer for Breast and Lung Cancer and Vice Chair of the Breast Cancer Committee for the SWOG Cancer Clinical Trials Network. She is committed to improving quality of life for patients with cancer, and is co-Founder of Team Survivor Northwest, a non-profit aimed at helping female cancer survivors improve their health through fitness and exercise, and the Women’s Empowerment Cancer Advocacy Network (WE CAN) to support cancer advocacy and education in low- and middle-income countries. https://www.ourmbclife.org/episodes/tat-the-tapur-study monthly 0.5 2025-02-10 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/2c5cdba2-f908-4826-b6fc-f5c2cdec109f/Schilsky+2.jpg Episodes - Tumor-Agnostic Therapies: Is The TAPUR Study Right For You? - Richard L. Schilsky, MD, FSCT, FACP, FASCO Dr. Schilsky is Professor emeritus at the University of Chicago having retired in 2021 from his position of Executive Vice President and Chief Medical Officer (CMO) of ASCO. Dr. Schilsky is also a Past President of ASCO, having served in the role during 2008-2009, and former Board member of Conquer Cancer, the ASCO Foundation. Before joining ASCO staff in 2013, Dr. Schilsky spent the majority of his career at the University of Chicago where he joined the faculty in 1984. Over the next nearly 30 years, Dr. Schilsky served in many leadership roles including as Director of the University of Chicago Cancer Research Center, Associate Dean for Clinical Research in the Biological Sciences Division and as the Chief the Section of Hematology/Oncology in the Department of Medicine. He is a highly respected leader in the field of clinical oncology and specializes in new drug development and treatment of gastrointestinal cancers. From 1995 to 2010, Dr. Schilsky served as chair of the Cancer and Leukemia Group B, a national cooperative clinical research group funded by the National Cancer Institute (NCI), now part of the Alliance for Clinical Trials in Oncology. He has extensive experience working with both the NCI and the Food and Drug Administration (FDA) having served as a member and chair of the NCI Board of Scientific Advisors, as a member of the NCI Clinical and Translational Research Committee, and as a member and chair of the Oncologic Drugs Advisory Committee of the FDA. Presently, he serves as chair of the Board of the Reagan-Udall Foundation for the FDA, and as a member of the Board of Directors of Friends of Cancer Research and of the European Organization for Research and Treatment of Cancer (EORTC). Dr. Schilsky has served on the editorial boards of many cancer journals, including the Journal of Clinical Oncology. He presently serves on the editorial board of the New England Journal of Medicine. Dr. Schilsky is the author of more than 450 original research articles, reviews and commentaries. https://www.ourmbclife.org/episodes/tat-paradigm-shift-in-cancer-care monthly 0.5 2025-02-25 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/981fbb9a-fb98-40ea-a77e-de09bc3db668/Josh+Drago+MSK+Headshot+High+Def+FINAL.jpg Episodes - Tumor-Agnostic Therapies: Is This a Paradigm Shift in Cancer Care? - Joshua Drago, MD, MS Dr. Drago is a Medical Oncologist and Breast Cancer specialist at Memorial Sloan Kettering Cancer Center. Dr. Drago’s research efforts include clinical and translational projects across breast cancer subtypes, with a special focus on HER2-positive breast cancer and antibody-drug conjugates. He has been the recipient of the Brian Piccolo Endowed Cancer Research Fellowship Award, Coltman Scholars Award, METAVIVOR Early Career Investigator Award, ASCO/Conquer Cancer Foundation Young Investigator Award, and the K12 Paul Calabresi Career Development Award for Clinical Oncology. Dr. Drago received his medical degree from Harvard Medical School, completed residency training in Internal Medicine at Massachusetts General Hospital, and finished Fellowship in Medical Oncology at Memorial Sloan Kettering Cancer Center. https://www.ourmbclife.org/episodes/report-back-from-asco-2024 monthly 0.5 2025-02-25 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/c10ac727-5f6a-4dac-97d4-0e94f6519c2d/Dr.+Kevin+Kalinsky+1.jpg Episodes - Report Back From ASCO 2024: What’s the Latest in HR+ MBC? - Kevin Kalinsky, MD, MS Dr. Kalinsky is Associate Professor in the Department of Hematology and Medical Oncology at Emory University School of Medicine. He serves as the director of the Glenn Family Breast Center at Winship where he is tasked with fulfilling the vision to improve breast cancer outcomes by aligning research and education with cancer treatment and prevention. Dr. Kalinsky received his medical degree from the Medical University of South Carolina and a Masters in Biostatistics, Patient Oriented Research Track from Columbia University Mailman School of Public Health. His training included a Residency and Medical Oncology Fellowship at Tufts-New England Medical Center, Breast Cancer Research Fellowship at Massachusetts General Hospital, and Breast Cancer Advanced Oncology Fellowship at Memorial Sloan-Kettering Cancer Center. Dr. Kalinsky's research involves the development of early-phase clinical trials to assess novel therapeutics in breast cancer based on tumor genomics. He has received the NCI Cancer Clinical Investigator Team Leadership Award, Physician of Impact Award by Komen Greater NYC, Ewig Clinical Scholar Teaching Award, and SWOG Career Engagement Award Twitter: @KalinskyKevin https://www.ourmbclife.org/episodes/mbc-matters-understanding-blood-test-results monthly 0.5 2025-02-25 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1721168979772-P722QQHKLSERM1BK2IMX/blood-tests-for-cancer.jpg Episodes - MBC Matters: Understanding Blood Test Results - blood-tests-for-cancer.jpg https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1721168688156-UXA8B49IW9XMXBR4EF1K/high-wbc-count.png Episodes - MBC Matters: Understanding Blood Test Results - high-wbc-count.png https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1721168722992-TWKQ8HJHHC8IYY049OJX/Normal%2BBlood%2BCount%2BNormal%2BValues%2BHb%2BM_%2Bg_L%2BF_%2Bg_L%2BRBC.jpg Episodes - MBC Matters: Understanding Blood Test Results - Normal+Blood+Count+Normal+Values+Hb+M_+g_L+F_+g_L+RBC.jpg https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/ddd95e4f-a8cd-46c9-ac45-b5fcf0a04c45/Image+2.jpg Episodes - MBC Matters: Understanding Blood Test Results - Alfredo Torres, MD Dr. Torres is the Associate Chief Medical Officer at NYCBS. He is board certified in Internal Medicine, Medical Oncology, and Hematology. He is fluent in English and Spanish. Dr. Torres received his Medical Degree from Universidad de Carabobo, Venezuela. He completed his residency in Internal Medicine through the prestigious Harrington Program from Jackson Memorial Hospital/University of Miami. In addition, Dr. Torres achieved his Fellowship in Medical Oncology and Hematology at Jackson Memorial Hospital/the University of Miami. Dr. Torres has published numerous studies in Hematology and Oncology in peer-reviewed medical journals. He was also a grant recipient from the Florida Breast Cancer Foundation. Dr. Torres is currently a member of several prestigious organizations including the American College of Physicians, the American Society of Clinical Oncology, the American Society of Hematology, and the Community Oncology Alliance. Dr. Torres is currently a Clinical Assistant Professor of Medicine at Stony Brook University Hospital. He has also served on the Chemotherapy committee at Jackson Memorial Hospital and he is currently a leader in the chemotherapy committee at NYCBS. His interests include lung cancer, gastrointestinal cancer, gynecological cancer, prostate cancer, and lymphomas. Credentials: Associate Chief Medical Officer , M.D. Education & Training Residency: Jackson Memorial Hospital Medical School: Universidad de Carabobo https://www.ourmbclife.org/episodes/conversation-with-dr-iyengar-balancing-a-healthy-lifestyle monthly 0.5 2025-02-10 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/8d4e9920-b80b-4040-bd65-779879f68980/Iyengar+photo.jpg Episodes - Balancing a Healthy Lifestyle with Eating Chocolate Cake: A Conversation with Dr. Iyengar - Neil Iyengar, MD Dr. Iyengar is a board-certified Medical Oncologist and clinical-translational researcher at Memorial Sloan Kettering Cancer Center (MSK) where he specializes in the care of patients with breast cancer. He also holds joint research appointments at the Rockefeller University Center for Clinical and Translational Science and Weill Cornell Medicine in New York. Dr. Iyengar received his undergraduate and medical degrees from the University of Illinois at Chicago accelerated degree program where he graduated with the College’s highest honors (University Scholar). He completed residency training in Internal Medicine at the University of Chicago Medical Center followed by fellowship in medical oncology and hematology at MSK. He now holds a faculty position as an Associate Attending on the Breast Medicine Service at MSK. Dr. Iyengar’s research program investigates interventions to improve metabolic health as a strategy to reduce breast cancer risk and mortality. His group is testing the anti-cancer effects of structured exercise and nutritional interventions in people at high risk or diagnosed with breast cancer. Dr. Iyengar’s research is also investigating the use of drugs that treat metabolic disorders, such as diabetes and obesity, to improve the effectiveness of cancer therapies. In an effort to rapidly translate this work, Dr. Iyengar also leads the MSK Healthy Living Program, a novel cancer care model that aims to translate research findings from lifestyle intervention trials into clinical practice during and after cancer therapy. His work has been recognized and awarded by several organizations, including research grants from the National Cancer Institute, American Cancer Society, the Breast Cancer Research Foundation, Conquer Cancer the ASCO Foundation, and others. He has published numerous original research articles and has been an invited speaker at several international conferences. You can find him on Twitter (X) @Neil_Iyengar https://www.ourmbclife.org/episodes/your-guide-to-bone-mets-exercise-yes-exercise monthly 0.5 2025-02-10 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/d220571c-99b1-47d8-ab35-190a87517db2/Bone+Mets+Exercise+Infographic.pdf.png Episodes - Your Guide to Bone Mets: Exercise (Yes, Exercise!) - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/c3db24d1-83c4-4f42-866c-d03eb41822e7/Kathryn+Schmitz+1.jpg Episodes - Your Guide to Bone Mets: Exercise (Yes, Exercise!) - Kathryn H Schmitz, PhD, M.P.H., FACSM, FTOS, FNAK Dr. Schmitz is a Professor in the division of Hematology and Oncology at the University of Pittsburgh School of Medicine. She serves as the Associate Director of Catchment Area Research, Co-leader of the Biobehavioral Cancer Control program and Director of the Exercise Oncology Initiative for the Hillman Cancer Center. Dr. Schmitz’s research focuses on people living with and beyond cancer and investigates the role of exercise in improving physiologic and psychosocial outcomes, including symptoms, treatment tolerance, and other chronic diseases. In addition, Dr. Schmitz studies technology based supportive care interventions (that include physical activity) to improve outcomes among advanced cancer patients. She has held NCI funding consistently since 2001. She has published over 350 scientific peer reviewed papers, some in prestigious journals such as JAMA, New England Journal of Medicine, and Journal of Clinical Oncology. Her well regarded research on resistance exercise and breast cancer related lymphedema has been translated into a physical therapy delivered program called ‘Strength After Breast Cancer’ that is available in over 1000 locations across the United States and beyond. Dr. Schmitz was the moving force behind two American College of Sports Medicine development processes for exercise and cancer guidelines for patients in 2010 and 2018. She founded the Moving Through Cancer initiative of the American College of Sports Medicine, which has a bold goal of making exercise standard of care in oncology by 2029. She has written a popular press book to raise awareness about exercise for cancer patients and survivors entitled ‘Moving Through Cancer’ that was released by Chronicle Books in October 2021. She is the winner of numerous awards, most notably the Distinguished Scientist Award from the Society of Behavioral Medicine, the Citation Award from the American College of Sports Medicine, and the Clinical Research Professorship from the American Cancer Society. In fall 2023, she was inducted as an Honorary Fellow at the Royal College of Surgeons in Edinburgh, Scotland. She is the past president of the American College of Sports Medicine. You can find her on IG @fitnessaftercancer & Twitter @fitaftercancer. https://www.ourmbclife.org/episodes/your-guide-to-bone-mets-traditional-and-innovative-approaches monthly 0.5 2025-02-10 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/599c3c82-2de2-4c63-8087-3e2a93ac8881/Pamkohltreatmentphoto+%281%29.JPG Episodes - Your Guide to Bone Mets: Traditional & Innovative Approaches Using Radiation - Pam Kohl A North Carolina native, Ms. Kohl has over 40 years of experience working in government and non-profit management. She served as Executive Director of the Susan G. Komen, North Carolina Triangle to the Coast Affiliate which serves 29 counties in NC. In that role, Pam was a passionate spokesperson and advocate for equitable breast cancer support services in Eastern NC and the vital need for breast cancer research. Her passion for finding the treatments/cures for metastatic breast cancer led to the development of the new Komen Metastatic Breast Cancer Collaborative Research Initiative. Pam recently retired but is continuing her advocacy as a volunteer. Pam was diagnosed with Stage 1 ER+ breast cancer in 2009. She had a lumpectomy, radiation and stayed on her endocrine therapy for 5 years. She had no family history and the Oncotype tumor analysis showed a very low risk for recurrence. In 2014 she was declared cancer free. However, in October 2016, she was diagnosed with breast cancer again and on January 31st 2017 she was diagnosed with State IV metastatic breast cancer. She is currently on an oral chemo drug and endocrine therapy and has bone scans and PET/CT scans every 12 weeks. Pam lives everyday knowing that it is breast cancer research that has prolonged her life and hopes that research will find the cures that will save her life. Pam was born and raised in Greensboro NC, graduated from Guilford College where she received the 2017 Guilford College Alumni Excellence Award. She is also a recipient of the Order of the Long Leaf Pine, which is presented to individuals who have a proven record of extraordinary service to the state of North Carolina. In May 2019, she was awarded the Coastal Federal Credit Union’s Power of Sharing Lifetime Achievement award for her many years of passionate work and leadership in the non-profit sector. Pam lives in Raleigh with her husband Tom Gongaware and she has two children, Max 32 and Sofie 29. You can find her on Twitter @PamLKohl https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/f239e97b-08b9-44af-b2f4-47ddbec0b14e/image001.jpg Episodes - Your Guide to Bone Mets: Traditional & Innovative Approaches Using Radiation - Rory Goodwin, MD, PhD Dr. Goodwin is the Director for Spinal Oncology, Surgical Director for the Duke Center for Brain and Spine Metastasis, Associate Program Director of the Neurosurgery Residency Program and an Associate Professor at the Duke University Medical Center. He attended the University of Florida where he majored in Neurobiological Sciences and Business Administration with minors in Chemistry and Economics. He obtained his M.D. and Ph.D. in Neuroscience from the Johns Hopkins University School of Medicine while also leading, founding, and participating in programs focused on future and current underrepresented minority students including serving as National President for the Student National Medical Association. He completed his Neurosurgery residency at the Johns Hopkins Hospital and has received research awards from the UNCF-Merck Science Initiative, the Burroughs Wellcome Fund, Robert Wood Johnson Foundation, and the NIH. Over the course of his training, he served as a Medical Officer for the Food and Drug Administration, Division of Orthopedic Devices, graduated from the Global Clinical Scholars Research Training Program at Harvard Medical School and also completed an in-folded Complex Spine Fellowship at The Johns Hopkins Hospital. In 2023, Dr. Goodwin was awarded the CNS DEI Impact award and recently received the Duke School of Medicine Research Mentoring in Equity, Diversity, and Inclusion Award. Dr. Goodwin has over 200 peer-reviewed manuscripts as well over 200 conference abstracts and presentations. He has a research interest in translational biomarkers and clinical outcomes for patients diagnosed with spinal tumors, and genomic and proteomic predictors in brain and spinal oncology. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/348b9e94-3c53-43b1-a679-aedb4c915768/Kalnicki+2.jpg Episodes - Your Guide to Bone Mets: Traditional & Innovative Approaches Using Radiation - Shalom Kalnicki, MD Dr. Kalnicki is a physician leader and radiation oncologist with a career that has focused on Cancer Service Line management for the last 18 years. Leading the Cancer Service Line for the Health System’s 11 Hospitals, he develops partnerships which express themselves through 14 multidisciplinary disease-based programs (screening, diagnostic, therapeutic and survivorship tracks), shared clinical and administrative resources, and centralized provider and patient support services. They establish clinical pathways (including clinical trials), improve timelines of care, track outcomes, prevent provider burn-out, and model value-based economic programs. As Chairman of Montefiore’s Cancer Committee, Dr. Kalnicki guides an interdisciplinary team of specialists focused on adherence to Commission on Cancer accreditation standards and who achieved the highest results in 2018. Their longtime personal interest in holistic cancer care translates into support programs minimizing the emotional and psychological impact of a cancer diagnosis on patients and their caregivers. As Professor and Chair of Radiation Oncology, he has been researching and implementing image-guided intensity-modulated radiation therapy, target motion management with 4-D radiation planning, functional radiation planning with PET-CT, as well as stereotactic body radiation therapy with its immunotherapy correlations. https://www.ourmbclife.org/episodes/your-guide-to-bone-mets-the-basics monthly 0.5 2025-02-10 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/f8e02a4e-aaa1-4f24-924e-ec61d707d0da/Dr+Monica+Fornier.jpg Episodes - Your Guide to Bone Mets: The Basics - Monica Fornier, MD Dr. Fornier is an Associate Member of the Breast Medicine Service of Memorial Sloan Kettering Cancer Center, and an Associate Professor at Weill Cornell Medical College. She specializes in the treatment of patients with breast carcinoma as well as bone health: she conducts clinical research, with particular regard to novel strategies for the preservation of bone health for both patients with early stage and metastatic disease. In this regard, she collaborates with scientists from Hospital of Special Surgery in NY, as well as other academic institutions. Dr. Fornier is an active member of various national and international scientific groups, including the American Society of Clinical Oncology, the European Society of Medical Oncology, The American Society of Bone and Mineral Research and the International Osteoporosis Foundation. Dr. Fornier has numerous publications to her name and has presented data at several meetings. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/3c9e74d7-5450-4649-9b86-c3723fbaaa8c/Farooki+1.jpg Episodes - Your Guide to Bone Mets: The Basics - Azeez Farooki, MD Dr. Farooki is an endocrinologist with particular interest in bone metabolism in people with cancer. He sees both patients with benign metabolic bone diseases, such as osteoporosis and hyperparathyroidism, and bone disorders due to advanced cancer, such as hypercalcemia and metastatic bone disease. Much of Dr. Farooki’s research has focused on rare complications of a subset of bone protective drugs known as antiresorptives. He has twice served on the National Comprehensive Cancer Care Network’s Bone Health in Cancer Care task force. https://www.ourmbclife.org/episodes/tissue-donation-you-can-help-advance-mbc-research monthly 0.5 2025-02-10 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/2bcff5bf-c444-4e40-9747-ab1da0d480a2/Rapid+Autopsy.png Episodes - Tissue Donation - You can help advance MBC research - Make it stand out Current Tissue Donation Programs for MBC in the United States (as of April 2024) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/fdd3a198-f105-468d-baa5-4bb14a1c980e/Hodgdon.jpg Episodes - Tissue Donation - You can help advance MBC research - Christine Hodgdon Christine Hodgdon was a conservation biologist before her metastatic breast cancer diagnosis in April 2015. Christine co-founded GRASP - Guiding Researchers & Advocates to Scientific Partnerships which empowers patients, clinicians, and researchers to exchange ideas and learn from each other. She spearheads the MBC Alliance-sponsored Breast Cancer Brain Metastasis (BCBM) Initiative: Marina Kaplan Project with the goal to address the unmet research needs of breast cancer patients living with central nervous system (CNS) metastasis and was a founding committee member of MBCBrainMets.org, a resource hub for breast cancer patients living with brain metastasis. She also collaborates with leadership at Johns Hopkins Sidney Kimmel Comprehensive Cancer Center to innovate the INSPIRE (Influencing Science through Patient-Informed Research & Education) Advocacy Program. Christine is very proud to be a patient advisor on the rapid autopsy tissue donation program, Hope for OTHERS (Our Tissue Helping Enhance Research & Science) at the University of Pittsburgh Medical Center (UPMC) Magee Womens Hospital. Hope for OTHERS offers patients the opportunity to leave a legacy by making contributions that will advance research discoveries and help future patients. You can find her on X (Twitter): @christeeny513 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/c0964ef4-b8cc-4b37-bd2a-2de44ff201c8/Lori+Miller+2.jpg Episodes - Tissue Donation - You can help advance MBC research - Lori Miller, B.S. Lori is was a research technician for 25 years (1980 - 2005) with the University of Pittburgh’s Chairman of Biochemistry, Klaus Hofmann. They were successful in isolating insulin receptor from human placentas. It was a huge discovery which made Lori fall in love with research. She then worked in transplant research, taking part in a gene therapy for arthritis research program in the 90s. Lori left the research field for 10 years, then returned to the University of Pittsburgh in 2016 as the biobanker, and now Clinical Coordinator for the Lee/Oesterreich lab. Although her previous research was cutting edge in exciting fields at the time, she feels they can’t hold a candle to the rapid autopsy program. Allowing patients to have the opportunity to leave their legacy in the world of breast cancer research is the most meaningful thing Lori feels she’s done in her career. Just as each patient is unique, so is each autopsy - in her words, “Every single one matters!!”. She is thankful for each and every patient willing to contribute to research. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/fc648712-2ab7-440b-bb6f-fdc7e8bb277c/Stephanie+Walker+3.png Episodes - Tissue Donation - You can help advance MBC research - Stephanie Walker Living with De Novo metastatic breast cancer since July 2015, Stephanie is a retired RN with close to 40 years experience in pediatric and adult critical care, as well as emergency department experience in critical access size hospitals to Level 1 trauma centers. Her last 14 years in nursing was spent in hospice/end of life care. After being diagnosed with MBC in 2018, Stephanie began to volunteer with many different breast cancer organizations. She is an independent advocate with the Metastatic Breast Cancer Alliance and the project lead of the BECOME (Black Experience of Clinical Trials and Opportunities for Meaningful Engagement) initiative. She was also instrumental in the planning and participation in the Black Wo(men) Speak Symposium held in conjunction with SABCS 2022. She is also a Living Beyond Breast Cancer Hear My Voice graduate, as well as a helpline volunteer. She is also a Project Lead grad of 2022. She is the Co-Chair of the working group that focuses on removing barriers to standard of care and quality of life. Stephanie will answer any questions, even the hard ones regarding her own mental health. She isn’t defined by her cancer and wants others to be their own light to shine bright. She is married with adult children & grandchildren, and lives with husband John and rescue dog Rex in eastern North Carolina. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/cca60f2f-5200-4ce6-bac4-10312bf89c85/Dr.+Steffi.jpeg Episodes - Tissue Donation - You can help advance MBC research - Steffi Oesterreich, Ph.D. Dr. Oesterreich is Professor of Pharmacology and Chemical Biology, Co- Leader of the Cancer Biology Program at UPMC Hillman Cancer Center (HCC), and Co-Director of the Women’s Cancer Research Center at Magee Women’s Research Institute and HCC. Her research focuses on progression of estrogen receptor positive breast cancer. Specific areas of interest include endocrine resistance, metastases, and invasive lobular carcinoma (ILC). Dr. Oesterreich has published more than 200 articles, her work has been continuously supported by the National Cancer Institute, CDMRP, BCRF, Susan G Komen and a number of other foundations. She is a Komen Scholar, and serves on the Scientific Advisory Board for BCRF. She enjoys working in multi-disciplinary teams, is interested in involvement of advocates in research, and is committed to mentoring the next generation of breast cancer researchers. https://www.ourmbclife.org/episodes/mbc-care-in-the-middle-of-nowhere monthly 0.5 2025-02-10 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/366f3e62-0fcd-45b4-92ba-a64d3f013b01/Evelyn+Sharpe+2.jpeg Episodes - MBC Care in the Middle of Nowhere - Evelyn Sharpe Evelyn was initially diagnosed with early stage breast cancer in February of 2014, followed by a recurrence in February of 2019. She then had metastasis to the right side of her brain in March of 2023. She is currently receiving chemotherapy and will receive radiation again for a spot on the left side of her brain. Although she is going through tough times, her faith in God and love of life provides her the strength to get through, one day at a time. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/04f07f5c-a4a5-477f-9fa5-08da3d5d3328/Kristin+2.jpg Episodes - MBC Care in the Middle of Nowhere - Kristin Kilmer Kristin is a wife and mother who works full-time leading communications and outreach for the South Dakota Department of Human Services while juggling treatments for metastatic breast cancer. Her start in advocacy began when she was diagnosed with Stage IIB breast cancer in 2011. Kristin pursued participation in a clinical trial as she believes research is the only way we will be able to successfully treat breast cancer in the future. After she was diagnosed with metastatic breast cancer in 2015, her interest in research advocacy increased. Due to a lack of options and support in her rural location, she currently drives nearly 800 miles every six weeks to meet with her oncology team and receive treatment. Kristin has spoken with numerous media outlets, including Cancer Today and Kaiser Health News, which led to a front-page feature in USA Today about the promise and limitations of precision medicine and the need for increased research funding. Kristin also participated in Living Beyond Breast Cancer’s Hear My Voice (HMV) Program in 2017 and in National Breast Cancer Coalition’s Project LEAD in June 2019. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/04a26690-e6f3-4d33-9b05-dbc8c4af28d0/Mina+2.jpeg Episodes - MBC Care in the Middle of Nowhere - Mina Eningowuk Mina, an Inupiaq from the Native Village of Shishmaref, Alaska, has had a remarkable journey. With a passion for working with children, Mina dedicated 13 years as an educational aide in elementary education. This experience allowed Mina to make a positive impact on the lives of many young learners. Mina was diagnosed with stage 4 Invasive Lobular Carcinoma in February of 2018 and shares har diagnosis with family, friends and other MBC patients through Facebook support groups. Despite facing the challenges of stage 4 Invasive Lobular Carcinoma, Mina's strength and resilience shine through. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/bffc6b1f-ab10-4a64-bc7c-9e6f85b34ca3/V+Fisher+1.jpg Episodes - MBC Care in the Middle of Nowhere - Veronica Fisher Veronica is currently 54 years old and has been living with metastatic breast cancer for the past 9 years. In 2020, she completed advocacy training for Living Beyond Breast Cancer. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/d704895b-fe74-4466-bf74-d604be0dbbb2/D+Belle+1.jpg Episodes - MBC Care in the Middle of Nowhere - Denise Bell, PhD, MPH Dr. Belle serves as the Development Director with Rural Health Group, Inc. Her role entails grants and relationship management, serving on various committees/coalitions, and is the organization’s community health center/research advocate. Dr. Belle has been a public health professional for 20+ years . Her research focuses on Black women living in rural, isolated areas and finding ways to cope with breast cancer. She has passion for minority rural communities. She would like to see more representation of minorities in clinical trials, research studies, and their voices included in the scientific literature. In addition, she desires meaningful research, equity – all aspects of life (income, environment, health care, etc.), and social change. In her spare time she cycles, gardens, loves spending time with her Mom and fur babies (two dogs), and is currently training for her first triathlon. You can find her on LinkedIn. https://www.ourmbclife.org/episodes/pi3king-the-right-target monthly 0.5 2025-02-10 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/b1b6fc46-7951-4c36-9816-549dadd67a99/Marlena+Murphy+2.jpg Episodes - PI(3)King the Right Target - Marlena Murphy Marlena Marlena Murphy was diagnosed with stage III triple-negative breast cancer in 2018. She maintained a positive attitude throughout treatment and found herself encouraging friends upon hearing her news. Marlena found her way to the advocacy world because of her desire to help others dealing with cancer. She began serving as a Patient Advocate in 2019 with My Style Matters while undergoing treatment. She also serves as a Patient & Family Advisor for Emory Winship Cancer Institute; works as a Program Manager for GRASP - Guiding Researchers and Advocates to Scientific Partnerships; and works as the Community Advocate for TurningPoint Breast Cancer Rehabilitation. As a result of her diagnosis and desire to help people, Marlena went back to school to pursue a Master's degree. In 2022, her last year of graduate school, she was diagnosed with Metastatic TNBC. In May 2023, she received a Master's in Clinical Mental Health Counseling with certificates in Marriage & Family Therapy and Sex Therapy. She is also a 2023 Project Lead graduate. Currently, Marlena provides therapy services to individuals experiencing homelessness. Soon, she will be providing counseling services for breast cancer patients and survivors at TurningPoint through a grant-funded initiative in downtown Atlanta. Twitter: @MarlenaDM https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/59419b61-2cf5-4792-9571-b3078413242d/Melanie+Sisk+1.jpg Episodes - PI(3)King the Right Target - Melanie Sisk Melanie was a wife, mom of two young boys and working full-time as a Registered Nurse when she was diagnosed with Stage 1A Breast Cancer at the age of forty-three. She completed her recommended surgery and radiation and was on endocrine therapy. Melanie thought she had put cancer behind her because she did everything right. However, she was diagnosed with Metastatic Breast cancer at the age of forty-seven. Much to her surprise, she was in the twenty to thirty percent of early-stage breast cancer patients that will be diagnosed with metastatic disease. Melanie was never educated on this high reoccurrence percentage. Due to her Metastatic treatment protocol and disease, she retired from her nursing career. Melanie has dived into advocacy work with an urgency to do what she can, while she can. She helped to start and moderate a local support group in her area of North Carolina called “Piedmont Triad METsters.” She is a trained volunteer with Cancer Services, a Peer to Peer Support Group Leader and Light Up MBC State Ambassador METAvivor. a Living Beyond Breast Cancer 2023 Hear My Voice MBC leadership alumna, mentor with Project Life. a part of the MBC Leadership Committee for Surviving Breast Cancer, and an individual member of the MBCAlliance. She is also a part of the new initiative, PIK3CA Pathbreakers. She is hoping to learn from others and help further the cause and mission of the Metastatic Breast Cancer community. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/70767358-8b9c-4abe-838d-0a6ad29d2d6d/Dr.+Vasan+1.jpg Episodes - PI(3)King the Right Target - Neil Vasan, MD, PhD Dr. Vasan is a breast oncologist, physician scientist, and Assistant Professor of Medicine in the Division of Hematology & Oncology at Columbia University, where he also serves as the Principal Investigator at the Vasan Laboratory of Functional Cancer Genomics at the Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center. He is a Member of the Breast Cancer Program at Columbia University Medical Center, where he treats breast cancer patients with standard-of-care therapies and on clinical trials. His laboratory uses functional genomics to understand how proteins regulate breast cancer cell signaling, growth, and therapeutic response. Neil received his AB/AM from Harvard University and his MD/PhD from Yale University School of Medicine, and he completed clinical training in internal medicine at Massachusetts General Hospital and in medical oncology at Memorial Sloan Kettering Cancer Center. As a postdoctoral fellow, he identified double PIK3CA mutations as an oncogenic alteration, which has gone from bench to bedside as a cancer genomic biomarker. His research awards include the 2023 NIH Director's New Innovator Award (DP2), NIH/NCI Mentored Clinical Scientist Development Award K08, Susan G. Komen Career Catalyst Research grant, American Association for Cancer Research (AACR) NextGen Star, and American Society for Clinical Investigation (ASCI) Young Physician-Scientist Award. Neil is an active clinical oncologist treating patients with breast cancer, and is the Scientific Advisor for PIK3CA Pathbreakers, a breast cancer patient advocacy group. He serves on the planning committee of the San Antonio Breast Cancer Symposium and as a Standing Member of the Oncologic Drugs Advisory Committee (ODAC) for the FDA. Twitter: @NeilVasan https://www.ourmbclife.org/episodes/report-back-from-sabcs-2023 monthly 0.5 2025-02-10 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/afe1ab97-0404-42ed-ab23-f2c60d491cdc/Timothy+Pluard.jpg Episodes - Report Back from SABCS 2023: Spotlight on the Latest in MBC - Timothy Pluard, MD Dr. Pluard is a breast oncologist who focuses exclusively on metastatic breast cancer. He is the founder and director of the Saint Luke’s Koontz Center for Advanced Breast Cancer. The Koontz Center was among the first centers to focus exclusively on the comprehensive care of patients with MBC. An extensive research program focused on new therapeutics for MBC has contributed to multiple new approved treatments that have significantly improved outcomes in metastatic breast cancer. The Koontz Center also imbeds psychology, nutrition, physical therapy/exercise and social work support into the routine care of MBC patients. https://www.ourmbclife.org/episodes/remembering-natalia monthly 0.5 2025-02-10 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/7111334b-4594-431b-99e3-59672c8da11c/Natalia+Green+1.jpg Episodes - Remembering Natalia - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1706633362210-982VG8RK3MJ4FYR8I1R5/Natalia+Art+4.jpeg Episodes - Remembering Natalia - Natalia Art 4.jpeg https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1706633362174-2OZ1TPGO147GP3X9MXEZ/Natalia+Art+2.jpeg Episodes - Remembering Natalia - Natalia Art 2.jpeg https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1706633363085-41LQ15VBQSUJA6K65GK0/Natalia+Art+3.jpeg Episodes - Remembering Natalia - Natalia Art 3.jpeg https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1706633360895-C9GDDIXEY20POVBBC8RM/Natalia+Art+1.jpeg Episodes - Remembering Natalia - Natalia Art 1.jpeg https://www.ourmbclife.org/episodes/think-joy-thursday-episode-4 monthly 0.5 2024-02-09 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/757c3f36-c75d-44bf-a0a7-43b702428761/Dar+Finkelstein+Headshot.jpg Episodes - TJT with Dar #4: Finding the Joy in Celebrations - Dar Finkelstein Dar is the self-proclaimed Queen of Joy! Since her MBC diagnosis in 2019, she has made having joy, sharing joy and teaching others how to have joy in their life her mission. Her passion for joy has led her to give back to the MBC Community. In addition to being a regular contributor to the Our MBC Life podcast, she founded the Charlotte Metsters Support Group, is a mentor with CarolinaBreastFriends.org, Levine Cancer Institute, and ProjectLifeMBC.org. She is a 2021 graduate of the LBBC.org Hear My Voice program and a member of the Mecklenburg Breast Health Coalition. She also uses her new found hobby of painting cards to raise funds for GoJenGo.org, a local organization providing financial assistance to those of all stages undergoing breast cancer treatment. For more joyful inspiration, join Dar on IG - @ChooseToLiveWithJoy FB - facebook.com/groups/makingourbestmbclife facebook.com/groups/choosetolivewithjoy https://www.ourmbclife.org/episodes/traveling-with-mbc-tales-and-tips monthly 0.5 2025-02-05 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/dc2bf940-3fc7-4292-b1f5-83f647e2ff58/Ashley+Fernandez+3.jpeg Episodes - Traveling with MBC: Tales & Tips - Ashley Fernandez Ashley was diagnosed with Denovo Metastatic breast Cancer at the age of 31 in April 2018. Ashley is a fierce thriver who has been living with MBC while being a full time mom to her daughter, Davyn, and wife to her husband, Carlos. Carlos is Active Duty Air Force, so they are currently stationed in North Carolina. Ashley is also a powerful prayer partner and is active with the local church. Ashley has done MBC advocacy through 2018 Ohio Metsquerade, Komen Public Policy, Public Speaking, Metavivor where she was one of the faces of their newest campaigns and Komen. She's always looking for opportunities to educate and empower others to advocate for the best possible health care, You are worth all good things in this world! She believes in living life colorfully, full of adventure and with intention. All MBC patients should be able to create memories and meet important milestones in their lives which is only possible with research. She continues to educate and remind others those living with MBC are not statistics or shells, but people. 116 People die a day with MBC , Stage 4 truly needs more funding. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/07ea56b4-9b92-4c44-9bec-ece39190fe67/Lesley+Glenn1.jpeg Episodes - Traveling with MBC: Tales & Tips - Lesley Kailani Glenn Passion, motivation and personal experience of living with Metastatic Breast Cancer for the past 10.5 years is what drives Lesley’s desire to be an advocate. Her goal is to partner with communities, researchers and organizations to aid with the funding of research, raising awareness, and providing support to the overlooked community of those who also live with Metastatic Breast Cancer. With a bachelors of Science in Organizational Leadership, she has been actively involved in advocacy since 2015, training with the inaugural Hear My Voice Volunteer class presented by Living Beyond Breast Cancer. She was invited back as a mentor in 2018 and was awarded the Living Beyond Breast Cancer Leadership Volunteer Award in the Fall of the same year. She enjoys working with researchers and other stakeholders in the MBC field. She is a member of the Metastatic Breast Cancer Alliance, Susan G. Komen’s Advocates in Science, the scientific advisory committee for the Love Research Army, and a consumer reviewer with the DOD-CDMRP, PICORI and Komen. She recently launched her biggest endeavor, Project Life, a virtual wellness house for those living with MBC and their loved ones. Lesley currently lives in the Rogue Valley of Southern Oregon with her rescue pup and 2 rescue cats. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/3d628c7e-d161-46ba-b2f3-2c944150d0a4/Sheila+Johnson+1+%282%29.jpeg Episodes - Traveling with MBC: Tales & Tips - Sheila Johnson When it comes to health equity and breaking down systemic barriers to care in the metastatic breast cancer community, Sheila Johnson is an inspiration to us all. Not only has Sheila been living with metastatic breast cancer for 13 years, she is also a 25-year United States Air Force military veteran. With African American women dying 42% faster than any other race, Sheila has used her own experiences to enhance care for others and tackle this worrying statistic. Sheila is wholly committed to ensuring that not only is health equity awareness raised, but that people from marginalized and minority groups are included in conversations about their care. Sheila’s efforts are staggering and relentless. She has held positions as an ambassador, advocate and mentor with Living Beyond Breast Cancer, Young Women’s Initiative, National Breast Cancer Coalition, Shades of Brown Foundation, and The Metastatic Breast Cancer Project amongst others. Sheila is a Patient Insights Board member for Medidata bringing her voice to recruitment and inclusion of clinical trials to the African American community. She is also a Consumer Reviewer for METAvivor and the DOB Breast Cancer Research Program. Sheila exemplifies inclusion, and despite her own ongoing health issues, she has given her time selflessly to engage and include others. She has spearheaded projects that have served to enhance diversity and promote equality, including being part of the Susan G. Komen Advocates In Science Program and as a Komen Scholar. Sheila’s remarkable story has been featured online for A Story Half Told, and in publications including The Breast Cancer Wellness Magazine Winter 2018 Edition “Ending Disparity”, and “O” The Oprah Magazine September 2020 Edition “An Air Force Vet’s Hardest Fight Yet.” Sheila is now a published author of “A Survivor’s Lens”, A Metastatic Breast Cancer Survivor’s Focus on Gods Word and Faith.” Sheila’s resiliency and energy are contagious, and she delivers excellence in all aspects of her life, personal and professional. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/6983ecdc-4528-4c6f-946b-90398b113391/Kelly+Shanahan+1.jpeg Episodes - Traveling with MBC: Tales & Tips - Kelly Shanahan In 2008, Kelly Shanahan had everything going for her: a busy and successful ob-gyn practice; a precocious 9 year old daughter; and a well used passport from traveling all over the world with her family to attend conferences, with a liberal dose of vacation on the side. When she was diagnosed with stage IIB breast cancer, she considered it a mere bump in the road. And for five years, breast cancer was an aside, something to put in the past medical history section of forms. Even when she developed sudden back pain, Kelly never thought it could be breast cancer rearing its ugly head – a pulled muscle, a herniated disc maybe, but not what it turned out to be: metastatic breast cancer in virtually every bone in her body, with a fractured vertebrae and an about to break left femur. Kelly was diagnosed in 2013, on her 53rd birthday. Neuropathy from the chemo cost her her career, but she has found a new purpose in advocacy. Kelly is on the board of METAvivor, a member of the Metastatic Breast Cancer Alliance, a Komen Advocate in Science, on the symptom intervention committee of the Alliance for Clinical Trials in Oncology, a grant reviewer and research advocate. She is passionate about getting patients to the table in the design, implementation, and follow up of clinical trials. Follow her on Twitter @stage4kelly. Kelly Shanahan is a mother, a wife, a daughter, a doctor, a woman LIVING with metastatic breast cancer. https://www.ourmbclife.org/episodes/understanding-progression-esr1-mutations monthly 0.5 2025-02-05 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/8953ec3e-90f1-47e4-81e4-8e8423f6b6df/virgina+kaklamani.jpg Episodes - Understanding Progression: How to Identify & Treat ESR1 Mutations in HR+ MBC - Virginia Kaklamani, MD Dr Kaklamani is Professor of Medicine in the Division of Hematology/Oncology at the University of Texas Health Sciences Center in San Antonio and is the Leader of the Breast Cancer Program at the Mays Cancer Center. Dr Kaklamani completed her medical training with honors at the University of Athens and her residency in Internal Medicine at Newton-Wellesley Hospital in Boston, MA. She completed her fellowship in hematology/oncology at Northwestern University. She also received a Master of Science in Clinical Investigation from Northwestern University. She was Head of the Translational Breast Cancer Program at Northwestern University and co-director of the cancer genetics program at the same institution. Dr Kaklamani has also served as the Associate Director for Clinical Research at UT Health San Antonio. Her research interests include designing clinical trials with targeted agents. Dr Kaklamani has also identified several genetic mutations that link obesity and breast cancer. https://www.ourmbclife.org/episodes/mtnbc-unicorns-living-in-contradiction monthly 0.5 2025-02-05 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1425c420-affa-4481-9566-96ca41e950c1/IMG_0583.jpg Episodes - mTNBC Unicorns: Living In Contradiction - Toni Willis, MD Toni was diagnosed with Triple Negative Breast Cancer in 2013 and with a TN metastatic recurrence in 2015. She is a 2022 graduate of the LBBC Hear My Voice Metastatic Advocacy Program. Through this program she found her voice in the metastatic breast cancer community. She has served as a panelist on the following LBBC webinars: Living Long-Term with MBC: A Panel Discussion on the Tough Stuff; Discussing Breast Cancer with Kids: Creating a Roadmap with Your Patients; and Minimizing Disparities in Breast Cancer (Medscape/LBBC). Toni is a physician and her advocacy interests are improving access to care and increasing patient involvement in clinical trials. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/31882712-fad0-4842-a267-86aca4a2f5ab/image_6487327+%285%29.JPG Episodes - mTNBC Unicorns: Living In Contradiction - Colleen Broughton Colleen has been living with Triple Negative Breast Cancer for 10 years (including 8 years with metastatic TNBC), and is grateful for the connections she’s found with other people living with cancer. She trained with Living Beyond Breast Cancer (LBBC) and is a breast cancer national helpline volunteer, often focusing on triple negative MBC. Colleen also leads the Alumni Ambassador program for A Fresh Chapter, an organization focused on helping people living with cancer build skills in resilience. Colleen is a mama of 3 and a Seattle native with a long tenure in healthcare marketing, curating memorable field trips, and hugging. *During the height of the pandemic, Colleen bought a unicorn costume so she could safely hug her children & their friends. She ended up bringing joy everywhere she went. This is the picture she sent us of her in it! https://www.ourmbclife.org/episodes/tony-laudico-one-year-without-lisa monthly 0.5 2025-02-05 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/b7f45adf-d5ac-4c51-9cd7-ee51848b8c18/Laudico_Anthony.jpg Episodes - Tony Laudico: One Year Without Lisa - Anthony (Tony) Laudico, BS, MBA Anthony (Tony) Laudico is the husband of the late Lisa Manning Laudico, founder of this podcast and fearless patient advocate who died on August 6th, 2022, after five years of living with metastatic breast cancer. Tony has a B.S. in electrical engineering from Columbia University and an M.B.A. in finance from New York University. He is the founder of Spencer Stuart’s global Digital Practice, and an executive recruiter who has recruited more than 200 senior-level digital and technology executives across multiple industries, geographies and functions. A former senior executive in the technology and digital industry, he has authored a number of professional articles and is a frequent speaker at digital conferences. Earlier in his career, Tony served in a variety of international business roles at Microsoft Corporation, including director of international business based in Tokyo, and director of systems marketing for Asia Pacific, based in Sydney. In all, he has worked in more than 30 countries around the world. Lisa and Tony met in Tokyo, where they were both employed. August 12th, 2022 ,would have been their 27th wedding anniversary. He and Lisa lived in Connecticut with their family dog Kita, and have two adult sons Matthias and Alexander. https://www.ourmbclife.org/episodes/think-joy-thursday-episode-3 monthly 0.5 2024-02-09 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/757c3f36-c75d-44bf-a0a7-43b702428761/Dar+Finkelstein+Headshot.jpg Episodes - TJT with Dar #3: Gratitude and it’s Importance in Living a Joyful Life - Dar Finkelstein Dar is the self-proclaimed Queen of Joy! Since her MBC diagnosis in 2019, she has made having joy, sharing joy and teaching others how to have joy in their life her mission. Her passion for joy has led her to give back to the MBC Community. In addition to being a regular contributor to the Our MBC Life podcast, she founded the Charlotte Metsters Support Group, is a mentor with CarolinaBreastFriends.org, Levine Cancer Institute, and ProjectLifeMBC.org. She is a 2021 graduate of the LBBC.org Hear My Voice program and a member of the Mecklenburg Breast Health Coalition. She also uses her new found hobby of painting cards to raise funds for GoJenGo.org, a local organization providing financial assistance to those of all stages undergoing breast cancer treatment. For more joyful inspiration, join Dar on IG - @ChooseToLiveWithJoy FB - facebook.com/groups/makingourbestmbclife facebook.com/groups/choosetolivewithjoy https://www.ourmbclife.org/episodes/young-adults-and-mbc monthly 0.5 2025-02-05 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/a92bde1a-8791-4647-91bb-b49eb5d64914/A+Valdez+1.jpg Episodes - Young Adults & MBC - Angelica Valadez Angie was born in Puebla, Mexico, raised in Houston, went to college in DFW, and finally settled in Austin, TX. She lives with her husband, Luke and dog, Crew. They hope to one day grow their family through fostering. Angie is a proud auntie to her niece, Lulu and nephew, Jojo. They mean the world to her. Angie is the middle child and enjoys being social and helping in her community. She loves trivia, dance parties and film. Her favorite pastime is trying new restaurants with her hubby as they bond over their shared appetites for fine dining. In her career, she has worked in the non-profit sector helping at-risk youth and families in the Austin area. On March 24th 2020, Angie was first diagnosed with stage 2B HER2+ breast cancer. She underwent chemotherapy, lumpectomy, radiation, hormone therapy, axillary lymph node dissection and oophorectomy. Angie was NED for 11 months then in April 2022, after having pneumonia for 8 weeks, she was diagnosed with Stage 4 BC with Mets in the liver. She underwent multiple plural drains and a pericardial window. She’s also undergone 3 lines of chemotherapy and most recently full brain radiation due to having 30 tumors in her brain. Angie is still fairly new to not only the breast cancer world in general, but also to the metastatic breast cancer community. This year, she was able to attend Camp Breastie and it changed her life. She hopes to use the support of this new found sisterhood to learn how to advocate for Latine people with MBC . You can find her on IG @southaustinhoney https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/a3822673-fda4-486f-8966-b2199683d64d/Sooz+Steever+2.jpg Episodes - Young Adults & MBC - Susan “Sooz” Stever Sooz has been a State Leader and Face 2 Face Leader with Young Survival Coalition for the state of Utah since 2017. She has completed the Young Advocate training with the Living Beyond Breast Cancer organization as well as been an ambassador for the Triple Negative Breast Cancer Foundation. Sooz attended the San Antonio Breast Cancer Symposium last year and has enjoyed working as an advocate within the breast cancer community. You find Sooz on IG @sooz_stever & FB at Sooz Stever Links: https://youngsurvival.org/ https://www.lbbc.org/ https://tnbcfoundation.org/ https://www.sabcs.org/ https://www.ourmbclife.org/episodes/meditation-mondays-7 monthly 0.5 2024-02-09 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/333e3445-e6bf-44cd-98d6-ca4094ba7a5b/Barbara+Chutroo+2.jpeg Episodes - Episode 7: Meditation Mondays with Barbara Chutroo - Barbara Chutroo Barbara Chutroo has made use of SHARE’s services since her first diagnosis in 2015 and is eternally grateful for all the support she has received. She is a clinical social worker and movement therapist who worked with severe and persistent mental illness in the South Bronx for thirteen years. She also taught psychology and child development at NYC College of Technology. She is especially interested in the integration of body and mind, an investigation she makes use of in her meditation practice. She began to study zen as an undergraduate in 1976 and has continued since then to explore various different meditation practices. The meditation community has provided her with valuable guiding principles for her life and personal growth. She was born and raised in New York City where she lives with her husband and two rescue cats. https://www.ourmbclife.org/episodes/we-remember-2023 monthly 0.5 2025-02-05 https://www.ourmbclife.org/episodes/think-joy-thursday-episode-2 monthly 0.5 2024-02-09 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/757c3f36-c75d-44bf-a0a7-43b702428761/Dar+Finkelstein+Headshot.jpg Episodes - TJT with Dar #2: What’s Perspective Got to Do With It? - Dar Finkelstein Dar is the self-proclaimed Queen of Joy! Since her MBC diagnosis in 2019, she has made having joy, sharing joy and teaching others how to have joy in their life her mission. Her passion for joy has led her to give back to the MBC Community. In addition to being a regular contributor to the Our MBC Life podcast, she founded the Charlotte Metsters Support Group, is a mentor with CarolinaBreastFriends.org, Levine Cancer Institute, and ProjectLifeMBC.org. She is a 2021 graduate of the LBBC.org Hear My Voice program and a member of the Mecklenburg Breast Health Coalition. She also uses her new found hobby of painting cards to raise funds for GoJenGo.org, a local organization providing financial assistance to those of all stages undergoing breast cancer treatment. For more joyful inspiration, join Dar on IG - @ChooseToLiveWithJoy FB - facebook.com/groups/makingourbestmbclife facebook.com/groups/choosetolivewithjoy https://www.ourmbclife.org/episodes/living-and-aging-with-mbc monthly 0.5 2025-02-05 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/ebc5a6c8-cda2-41e3-a89c-27d1f3ac9c38/RachelFreedmanPicture+%282%29.jpg Episodes - Living & Aging with MBC: Dr. Rachel Freedman & Patient Experiences - Rachel Freedman, MD, MPH Dr. Freedman is a medical oncologist in DFCI's breast oncology program and a clinical researcher. Her research focuses on improving the care of vulnerable patient populations who are under-represented in clinical trials and who are at risk for poor breast cancer outcomes, including older women and those who face challenges in access to care. In addition, she is interested in novel therapeutics, serving as the Principal Investigator for several clinical trials dedicated to older adults. She is also the founder and director of the Program for Older Adults with Breast Cancer at Dana-Farber. Dr. Freedman joined the faculty at Dana-Farber in 2009. She studied at Georgetown University School of Medicine and obtained her master’s in public health at the Harvard University T.H. Chan School of Public Health. Her research has been funded by Susan G Komen, ACS, NCI, Gateway for Cancer Research, METAvivor, and the Alliance for Clinical Trials Foundation. https://www.ourmbclife.org/episodes/meditation-mondays-6 monthly 0.5 2024-02-09 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/333e3445-e6bf-44cd-98d6-ca4094ba7a5b/Barbara+Chutroo+2.jpeg Episodes - Episode 6: Meditation Mondays with Barbara Chutroo - Barbara Chutroo Barbara Chutroo has made use of SHARE’s services since her first diagnosis in 2015 and is eternally grateful for all the support she has received. She is a clinical social worker and movement therapist who worked with severe and persistent mental illness in the South Bronx for thirteen years. She also taught psychology and child development at NYC College of Technology. She is especially interested in the integration of body and mind, an investigation she makes use of in her meditation practice. She began to study zen as an undergraduate in 1976 and has continued since then to explore various different meditation practices. The meditation community has provided her with valuable guiding principles for her life and personal growth. She was born and raised in New York City where she lives with her husband and two rescue cats. https://www.ourmbclife.org/episodes/report-back-from-asco-2023 monthly 0.5 2024-10-09 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/89518950-612f-4975-9cbf-c72e21a4550f/shen-sherry-221213-020_1200x800_rt.jpg Episodes - Report Back From ASCO 2023: What’s the Latest News in MBC Research? - Sherry Shen, MD Dr. Shen is a medical oncologist and clinical investigator on the Breast Medicine Service at Memorial Sloan Kettering Cancer Center (MSK). Her research focus is on targeting metabolic health to improve treatment efficacy and survival for patients with cancer. She is leading clinical trials investigating dietary strategies to mitigate PI3K inhibitor-associated hyperglycemia in patients with metastatic hormone receptor-positive breast cancer and testing a metabolically targeted treatment in combination with chemotherapy in patients with metastatic triple-negative breast cancer. She also heads the research aspect of the Healthy Living Program at MSK, a clinical program for patients with newly diagnosed early-stage breast cancer that provides comprehensive lifestyle assessment and multidisciplinary health support in parallel with cancer care, with the goal of determining the effect of lifestyle changes over time on cardiovascular and cancer outcomes. https://www.ourmbclife.org/episodes/think-joy-thursday-episode-1 monthly 0.5 2024-02-09 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/757c3f36-c75d-44bf-a0a7-43b702428761/Dar+Finkelstein+Headshot.jpg Episodes - TJT with Dar #1: The Difference Between Joy and Happiness - Dar Finkelstein Dar is the self-proclaimed Queen of Joy! Since her MBC diagnosis in 2019, she has made having joy, sharing joy and teaching others how to have joy in their life her mission. Her passion for joy has led her to give back to the MBC Community. In addition to being a regular contributor to the Our MBC Life podcast, she founded the Charlotte Metsters Support Group, is a mentor with CarolinaBreastFriends.org, Levine Cancer Institute, and ProjectLifeMBC.org. She is a 2021 graduate of the LBBC.org Hear My Voice program and a member of the Mecklenburg Breast Health Coalition. She also uses her new found hobby of painting cards to raise funds for GoJenGo.org, a local organization providing financial assistance to those of all stages undergoing breast cancer treatment. For more joyful inspiration, join Dar on IG - @ChooseToLiveWithJoy FB - facebook.com/groups/makingourbestmbclife facebook.com/groups/choosetolivewithjoy https://www.ourmbclife.org/episodes/roberta-lombardi-and-infinite-strength monthly 0.5 2025-02-05 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/e8e80ad6-d46f-468b-8168-cfb5679cbdb6/Deltra+2.jpg Episodes - Roberta Lombardi and Infinite Strength - Deltra James Deltra is a Connecticut based mama of 5 amazing girls who she strives to raise with cultural and health awareness. She's a chain tea drinker, wig hoarder, and lover of singing loudly and dancing unabashedly. Since being diagnosed with Triple Negative MBC de novo in 2019 she has focused on thriving through education, advocacy, connecting and radical self-care. She is passionate about mental and emotional wellness, creative expression as a means of coping, community building and connecting BIPOC women with people and spaces that can care for their whole selves. She is a member of Cactus Cancer Society's YAC advisory board, the inaugural class of For the Breast of Us Baddie Ambassador, the Our MBC Life podcast volunteer and serves as Diversity and Inclusion Coordinator for Project Life MBC. You can find Deltra at: IG - @deltra_does_it FB - deltra.tatiana https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/c1cf9c56-da06-45fc-8df5-c2fa34c60ba7/Marlena+Murphy+2.jpg Episodes - Roberta Lombardi and Infinite Strength - Marlena Murphy Marlena was diagnosed with stage III triple-negative breast cancer in 2018. She maintained a positive attitude throughout treatment and found herself encouraging friends upon hearing her news. Marlena found her way to the advocacy world because of her desire to help others dealing with cancer. She began serving as a Patient Advocate in 2019 with My Style Matters while undergoing treatment. She also serves as a Patient & Family Advisor for Emory Winship Cancer Institute; works as a Program Manager for GRASP - Guiding Researchers and Advocates to Scientific Partnerships; and works as the Community Advocate for TurningPoint Breast Cancer Rehabilitation. As a result of her diagnosis and desire to help people, Marlena went back to school to pursue a Master's degree. In 2022, her last year of graduate school, she was diagnosed with Metastatic TNBC. In May 2023, she received a Master's in Clinical Mental Health Counseling with certificates in Marriage & Family Therapy and Sex Therapy. Currently, Marlena provides therapy services to individuals experiencing homelessness. Marlena is also a 2023 NBCC Project Lead Graduate. Soon, she will be providing counseling services for breast cancer patients and survivors at TurningPoint through a grant-funded initiative in downtown Atlanta. You can find Marlena at: Twitter: @MarlenaDM https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/605e3331-18e4-416d-a288-40dd57fdf0cf/210_Roberta_Lombardi_2020-Edit_PRINT.jpg Episodes - Roberta Lombardi and Infinite Strength - Roberta Lombardi Roberta is a breast cancer survivor and an early stage ally to the MBC Community. She began Infinite Strength in 2018 to provide single mothers in active treatment for breast cancer with financial and emotional support. As the nonprofit grew, she understood the unique needs patients with MBC had and the lack of support and access to care for marginalized groups. Infinite Strength is the only breast cancer nonprofit in the country to provide recurring financial grants for single moms with MBC, while also providing support to their children as well. You can find Roberta at: Instagram - @strengthforhealing Twitter - @Robertalom3 @InfiniteMBC Facebook - Infinite Strength Linkedin - Infinite Strength https://www.ourmbclife.org/episodes/meditation-mondays-5 monthly 0.5 2024-02-09 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/333e3445-e6bf-44cd-98d6-ca4094ba7a5b/Barbara+Chutroo+2.jpeg Episodes - Episode 5: Meditation Mondays with Barbara Chutroo - Barbara Chutroo Barbara Chutroo has made use of SHARE’s services since her first diagnosis in 2015 and is eternally grateful for all the support she has received. She is a clinical social worker and movement therapist who worked with severe and persistent mental illness in the South Bronx for thirteen years. She also taught psychology and child development at NYC College of Technology. She is especially interested in the integration of body and mind, an investigation she makes use of in her meditation practice. She began to study zen as an undergraduate in 1976 and has continued since then to explore various different meditation practices. The meditation community has provided her with valuable guiding principles for her life and personal growth. She was born and raised in New York City where she lives with her husband and two rescue cats. https://www.ourmbclife.org/episodes/ombcl-shorts-dr-erika-hamilton monthly 0.5 2025-02-25 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/3357140b-3d6f-4e0e-96b6-e06d29fb30e8/Erika+Hamilton+1.jpg Episodes - OMBCL Shorts #2: Dr. Erika Hamilton with Top Takeaways from ASCO23 - Erika P. Hamilton, MD Director, Breast Cancer and Gynecologic Cancer Research, Sarah Cannon Research Institute(SCRI) She oversees the program and the clinical trial menu for these cancers across the SCRI network. Dr. Hamilton joined SCRI in 2013 as an investigator in drug development for women’s cancers, and has served as director of breast cancer and gynecologic cancer research since 2015. Her mother is a BC survivor, who was diagnosed with breast cancer when Dr. Hamilton was in middle school. Dr. Hamilton is passionate about personalized treatment, empowering her patients, and treating each person individually based on their goals and preferences. Dr. Hamilton received her undergraduate degree from Washington and Lee University in Virginia and received a NCAA Postgraduate Scholarship. She then completed her medical degree and residency from University of North Carolina in Chapel Hill and fellowship training in hematology and oncology at Duke University, where she was recognized as a Top 5 Finalist for Duke's Annual House staff Fellow Teaching Award. Dr. Hamilton was named to the Women to Watch Class of 2021 for Nashville Medical News. She was selected for the American Society of Clinical Oncology’s (ASCO) Leadership Development Class for 2021-2022, and was the past chair of ASCO’s Scientific Committee for Metastatic Breast Cancer for 2019-2020. She is the 2023-2025 Scientific Committee co-chair of the ESMO Breast Cancer Meeting, serves on ASCO’s Cancer Research Committee, ASCO’s Digital Content Committee, and is an associate editor for Clinical Breast Cancer. Dr. Stephanie Graff, MD, FACP https://www.ourmbclife.org/episodes/sarah-mandel-little-earthquakes monthly 0.5 2025-02-25 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/0fee66e7-17d7-43bb-814b-0652d79624cf/x500.JPG Episodes - MBC Life: Quakes, Aftershocks, and Hope - Sarah Mandel, P.D. Sarah Mandel is a licensed clinical psychologist based in New York City. She received her doctorate (Psy.D.) from Rutgers University and a B.A. in Studio Art from Bard College. She lives in Manhattan with her husband and two daughters. https://www.ourmbclife.org/episodes/meditation-mondays-4 monthly 0.5 2024-02-09 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/333e3445-e6bf-44cd-98d6-ca4094ba7a5b/Barbara+Chutroo+2.jpeg Episodes - Episode 4: Meditation Mondays with Barbara Chutroo - Barbara Chutroo Barbara Chutroo has made use of SHARE’s services since her first diagnosis in 2015 and is eternally grateful for all the support she has received. She is a clinical social worker and movement therapist who worked with severe and persistent mental illness in the South Bronx for thirteen years. She also taught psychology and child development at NYC College of Technology. She is especially interested in the integration of body and mind, an investigation she makes use of in her meditation practice. She began to study zen as an undergraduate in 1976 and has continued since then to explore various different meditation practices. The meditation community has provided her with valuable guiding principles for her life and personal growth. She was born and raised in New York City where she lives with her husband and two rescue cats. https://www.ourmbclife.org/episodes/living-in-the-public-eye-with-mbc monthly 0.5 2025-02-05 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/00fc49db-0632-47bb-81af-52c1fbb9431a/Kelly+Crump+2.png Episodes - Living in the Public Eye with MBC: An Interview with Kelly Crump - Kelly Crump Kelly was initially diagnosed in 2017 with early-stage breast cancer at age 38 after discovering a lump in her chest. She had no family history of the disease. In 2019, the cancer spread to her neck, lung, armpit, ribs and spine; she is currently on her seventh line of treatment. To cope, Crump took to social media, where she candidly shares her experience with others and has garnered a large dedicated following. Photo by Yu Tsai for Sports Illustrated, swimsuit by Asherah Swim. You can connect with Kelly on FB, IG, & Twitter: @itskellycrump https://www.ourmbclife.org/episodes/meditation-mondays-3 monthly 0.5 2024-02-09 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/333e3445-e6bf-44cd-98d6-ca4094ba7a5b/Barbara+Chutroo+2.jpeg Episodes - Episode 3: Meditation Mondays with Barbara Chutroo - Barbara Chutroo Barbara Chutroo has made use of SHARE’s services since her first diagnosis in 2015 and is eternally grateful for all the support she has received. She is a clinical social worker and movement therapist who worked with severe and persistent mental illness in the South Bronx for thirteen years. She also taught psychology and child development at NYC College of Technology. She is especially interested in the integration of body and mind, an investigation she makes use of in her meditation practice. She began to study zen as an undergraduate in 1976 and has continued since then to explore various different meditation practices. The meditation community has provided her with valuable guiding principles for her life and personal growth. She was born and raised in New York City where she lives with her husband and two rescue cats. https://www.ourmbclife.org/episodes/ombcl-shorts-dr-graff monthly 0.5 2023-08-08 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/f309c88d-4f79-4a98-9d9c-ea8fdc1ca1c2/S+Graff+1.jpg Episodes - OMBCL Shorts #1: Dr. Stephanie Graff & Her Steps For Those Newly Diagnosed MBC - Stephanie Graff MD, FACP Dr. Stephanie Graff, MD, FACP https://www.ourmbclife.org/episodes/rising-rate-of-bc-and-mbc-in-young-women monthly 0.5 2025-02-05 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/543dccd7-2598-4f12-a77f-9c533e770628/Virginia+Borges+1.jpg Episodes - The Rising Rates of BC & MBC in Young Women, Including Pregnancy & Post-Partum Diagnoses - Virginia Borges, M.D. Dr. Borges is a Professor of Medicine with Tenure at the University of Colorado Denver and holds the Robert C. and Patricia Young-Connor endowed Chair in Young Women’s Breast Cancer. Dr. Borges is the Deputy-Head of the Division of Medical Oncology, the Director of the Breast Cancer Research Program and the Director for the Young Women’s Breast Cancer Translational Program. Dr. Borges focuses on research in Young Women’s breast cancer, the interaction of breast cancer and pregnancy and the development of novel drugs for breast cancer. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1361a7fb-e383-4ade-aee3-f2b2a1c70378/RJ+headshot+photo+%281%29.jpg Episodes - The Rising Rates of BC & MBC in Young Women, Including Pregnancy & Post-Partum Diagnoses - Rebecca Johnson, M.D. Dr. Johnson is a physician in the division of Pediatric Hematology/Oncology at Mary Bridge Hospital in Tacoma, WA. Dr. Johnson founded the Adolescent and Young Adult (AYA) oncology program at Seattle Children’s Hospital and is now building an AYA program at Mary Bridge Hospital/MultiCare Health System. Her clinical and research interests include patient engagement, cancer epidemiology and unmet needs and barriers to care among AYAs. She chairs the AYA committee of the SWOG clinical trials group and serves on the advisory board of the Children’s Oncology Group (COG) AYA Committee. https://www.ourmbclife.org/episodes/rtac-current-trends-and-controversies monthly 0.5 2025-02-05 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/ea59fce7-f416-421a-8398-95309c9976ed/Screenshot+2023-05-30+at+10.36.24+PM.png Episodes - Recent Advances, Controversies, and Emerging Trends in MBC - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1685497801902-UCOE0W00I1XPAD30BWB4/cockapoo-puppy-laying-on-carpet-SW.jpg Episodes - Recent Advances, Controversies, and Emerging Trends in MBC https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1685497806127-AYA1FQ7BYWQK6AC7RMR4/licensed-image.jpeg Episodes - Recent Advances, Controversies, and Emerging Trends in MBC An adorable brown and white Bernedoodle puppy poses climbing on a skate board in this summer scene. Photo was taken June 6, 2021 in Salt Lake City, Utah https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1685497809458-QJ5L7X9NEGBPQOPO9XVV/dog_labradoodle_mobile.jpg Episodes - Recent Advances, Controversies, and Emerging Trends in MBC https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1685498143716-YRAMOA5SN7P8J1EPAWZX/black-labradoodle.jpg Episodes - Recent Advances, Controversies, and Emerging Trends in MBC https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/198c7458-9e6d-4154-bf74-e27f7a0c90c6/composition-x-1939.jpg%21Large.jpg Episodes - Recent Advances, Controversies, and Emerging Trends in MBC - Composition X Wassily Kandinsky Kandinsky's Composition X is a lovely piece that helps us consider the question guiding hormone receptor positive MBC right now, which is how do we fit all of these different shapes and colors and pieces of targeted therapy in the hormone receptor positive space together in the best shape and sequence to help patients stay on non-cytotoxic therapy in the most patient centered manner for the longest, https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/7db3b219-274a-4e5c-9faf-9665b1eda026/monet-rouen.jpg Episodes - Recent Advances, Controversies, and Emerging Trends in MBC - Rouen Cathedral Claude Monet What we know is that there are some very similar things and some very different things in the three FDA-approved CDK4/6 inhibitors. I previously compared them to Monet paintings, where he famously painted the cathedrals at Rouen across many years in different lights, at different times of day and seasons. And you see just the dramatic differences in the structure of the building. and that's how I feel about CDK4/6 inhibitors. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/f309c88d-4f79-4a98-9d9c-ea8fdc1ca1c2/S+Graff+1.jpg Episodes - Recent Advances, Controversies, and Emerging Trends in MBC - Stephanie Graff, MD, FACP Dr. Stephanie Graff, MD, FACP https://www.ourmbclife.org/episodes/meditation-mondays-1-7rjpc monthly 0.5 2024-02-09 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/333e3445-e6bf-44cd-98d6-ca4094ba7a5b/Barbara+Chutroo+2.jpeg Episodes - Episode 2: Meditation Mondays with Barbara Chutroo - Barbara Chutroo Barbara Chutroo has made use of SHARE’s services since her first diagnosis in 2015 and is eternally grateful for all the support she has received. She is a clinical social worker and movement therapist who worked with severe and persistent mental illness in the South Bronx for thirteen years. She also taught psychology and child development at NYC College of Technology. She is especially interested in the integration of body and mind, an investigation she makes use of in her meditation practice. She began to study zen as an undergraduate in 1976 and has continued since then to explore various different meditation practices. The meditation community has provided her with valuable guiding principles for her life and personal growth. She was born and raised in New York City where she lives with her husband and two rescue cats. https://www.ourmbclife.org/episodes/living-alone-with-mbc monthly 0.5 2025-02-05 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/5b63901c-c95e-4409-bd58-f32d34f81dcf/Lesley+Glenn1.jpeg Episodes - Living Alone with MBC - Lesley Kailani Glenn Passion, motivation and personal experience of living with Metastatic Breast Cancer for the past 10.5 years is what drives Lesley’s desire to be an advocate. Her goal is to partner with communities, researchers and organizations to aid with the funding of research, raising awareness, and providing support to the overlooked community of those who also live with Metastatic Breast Cancer. With a bachelors of Science in Organizational Leadership, she has been actively involved in advocacy since 2015, training with the inaugural Hear My Voice Volunteer class presented by Living Beyond Breast Cancer. She was invited back as a mentor in 2018 and was awarded the Living Beyond Breast Cancer Leadership Volunteer Award in the Fall of the same year. She enjoys working with researchers and other stakeholders in the MBC field. She is a member of the Metastatic Breast Cancer Alliance, Susan G. Komen’s Advocates in Science, the scientific advisory committee for the Love Research Army, and a consumer reviewer with the DOD-CDMRP, PICORI and Komen. She recently launched her biggest endeavor, Project Life, a virtual wellness house for those living with MBC and their loved ones. Lesley currently lives in the Rogue Valley of Southern Oregon with her rescue pup and 2 rescue cats. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/4d0c7aaa-de80-4dd4-a817-9ea67fcffd25/Beth+Harvey+1.jpeg Episodes - Living Alone with MBC - Beth Harvey Beth is a resident of Georgia. She took an early retirement, and left her career in Human Resources at the end of 2021. Beth is amicably divorced with no children and continues to have a friendly relationship with her ex, who continues to provide care for her dog when she’s unable to do so herself. She was first diagnosed with stage 1 breast cancer 2003, followed by a stage 2/3 recurrence 15 years later. A visit to the ER in 2021 showed “malignant pleural fluid” - what she initially thought was a chest infection was now a diagnosis of MBC. Beth is currently on her 4th line of treatment. This has given her a heightened sense of importance to plan for care as a single woman without family nearby. When the disease does not limit her from doing what she enjoys, Beth volunteers with her therapy dog at a local hospital, and is involved with Brittany Dog Rescue in Texas. She also leads a tech tips workshop at an assisted living facility. Another one of Beth’s biggest passions is traveling. She went on a bucket list trip to Antarctica this last December ‘22 thru January ‘23 and despite the possible adverse effects on her lungs from flying such a long distance, she highly recommends it as a must-see if you are given the opportunity. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/82444df6-59bf-4cf2-b6ba-d50c7b583d82/35946EF3-174A-4271-AF71-F43E1BE9CFD6.png Episodes - Living Alone with MBC - Sheila Pettiford Sheila Pettiford Bell has been living with Metastatic Breast Cancer (MBC) since April 2014. She was initially diagnosed with early-stage breast cancer in June of 2004. Sheila was treated at a major cancer center in Philadelphia PA with a mastectomy and chemotherapy. She returned to that same center after breast cancer was found in her lungs. Sheila ‘retired’ from teaching in April of 2014 to fight for her life and became active in the breast cancer community advocating for herself and others. Her first stop in her quest to learn more about MBC was the Cancer Support Community of Greater Philadelphia. Sheila also has found support, camaraderie and opportunities to volunteer with Enon’s Cancer Survivors, Supporters and Caregivers Ministry at her place of worship in Philadelphia, PA and Living Beyond Breast Cancer’s annual MBC conference. She has been a volunteer for several years during her journey with MBC with breast cancer awareness groups local to her hometown of Philadelphia such as Women of Faith and Hope, Praise Is The Cure and Youth Enrichment Programs, Inc. BC fundraising program. Their goals are to increase awareness about risks leading to breast cancer, new treatments and increasing survivorship in the African American community. She became active in Delaware’s Breast Cancer Coalition and keeps up with support groups on social media sites. Sheila also was honored to go to Capitol Hill in 2019 and virtually in 2020, sponsored by the Komen Foundation as part of their MBC Advisory Committee to share her story with legislators to garner support for Bills that would impact those living with Breast Cancer. She has shared her insights with the healthcare community about how to market information to MBC patients and completed several cancer studies. Sheila is committed to the fight to increase diversity in clinical trials for MBC patients. She volunteered with MBC Alliance’s BECOME Project in 2021 and participated in Black Wo(Men) Speak Symposium in San Antonio, TX in 2022 as a subcommittee member and shared her perspectives as an MBC patient. She now is an individual member. Sheila also was an honoree for Metavivor’s Be Bold and Behold fundraiser in 2022. The next step for Sheila Pettiford Bell in her new home in Virginia is to identify and work with others committed to helping people who live alone with stage 4 breast cancer specifically and addressing the numerous needs of all stage four patients in general. She has embraced the motto, “No one fights cancer alone”. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/5e6fa4b5-c0cf-40be-8538-930cd2d63813/Angela+Stratton+2.jpeg Episodes - Living Alone with MBC - Angela Stratton Angela is a 39 year old MBC patient first diagnosed with stage 3 breast cancer 9 years ago, and diagnosed with stage 4 recurrence in 2020. She has been living with bone and lymph node Mets since 2020 and will be celebrating 1 year stable on her first line of treatment in June 2023. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/bd41dc50-c6ce-40c9-ba95-9e496d1c2a22/Monica+Bryant+1.jpg Episodes - Living Alone with MBC - Monica Bryant, Esq. Monica Fawzy Bryant is a cancer rights attorney, speaker, and author, dedicated to improving access to and availability of quality information on cancer survivorship issues. Monica is the co-founder and Chief Operating Officer for Triage Cancer, a national, nonprofit organization that provides education on the practical and legal issues that may impact individuals diagnosed with cancer and their caregivers, through events, materials, and resources. Throughout her career, Monica has provided over one thousand educational seminars, written articles, blogs, appeared on radio and television shows, and co-authored a book published by the American Bar Association called Cancer Rights Law: An Interdisciplinary Approach. Monica is an Adjunct Law Professor at University of Illinois at Chicago School of Law, teaching a class on Cancer Rights. IG, FB, & Twitter: @TriageCancer LinkedIn: https://www.linkedin.com/company/triage-cancer/ Monica Bryant’s Twitter: @NavSurvivorship LinkedIn: https://www.linkedin.com/in/monica-bryant/ https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/5d16e12b-6c9c-4191-b301-d863f715ddda/Jane+Lowers+1.JPG Episodes - Living Alone with MBC - Jane Lowers, PhD, MPA Jane Lowers is an assistant professor in the Division of Palliative Medicine at Emory University in Atlanta. She holds a bachelors in journalism from Northwestern University, a masters in public administration from Baruch College in New York, and a PhD in palliative care from Lancaster University in England. Her work focuses on the differences between the care people want at end of life and the care they receive, and the factors that shape their choices. This has included a study on caregivers of people who chose to voluntarily stop eating and drinking to hasten death (or VSED) and current research on people aging without close family. https://www.ourmbclife.org/episodes/newly-diagnosed-with-mbc-dr-rebecca-shatsky monthly 0.5 2025-02-05 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/42ddf23e-a2fe-4b0d-ba41-7fe6bd0643d0/Rebecca+Shatsky+1.jpg Episodes - Newly Diagnosed with MBC: Tests, Terms, & Tips with Dr. Rebecca Shatsky - Rebecca A. Shatsky, MD Dr. Shatsky is a board-certified medical oncologist who specializes in treating breast cancer. She conducts clinical and translational breast cancer research at Moores Cancer Center at UC San Diego Health. She is the principal investigator of many clinical trials and is part of the national clinical operations leadership for the I-SPY-2 trial and ASCO metastatic breast cancer guideline panel. Her translational research focuses on the treatment of triple negative and lobular breast cancer and is funded by multiple sources, including grants from the California Initiative to Advance Precision Medicine and the Breast Cancer Research Foundation. Dr. Shatsky completed a hematology/oncology fellowship at UC San Diego School of Medicine. She completed her internal medicine residency at UCLA David Geffen School of Medicine and earned her medical degree from the Keck School of Medicine of the University of Southern California. She is board certified in internal medicine, hematology, and medical oncology. Twitter: @Dr_Rshatsky. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/ac60f21d-a524-4d3e-8003-b32cb8c290c1/Ashley+Fernandez+1.jpeg Episodes - Newly Diagnosed with MBC: Tests, Terms, & Tips with Dr. Rebecca Shatsky - Ashley Fernandez Ashley was diagnosed with Denovo Metastatic breast Cancer at the age of 31 in April 2018. She is a fierce thriver who has been living with MBC while being a full time mom to her daughter Davyn and wife to her husband Carlos. Carlos is Active Duty Air Force, they are currently stationed in North Carolina. Ashley is also a powerful prayer partner and is active with the local church. She has done MBC advocacy through 2018 Ohio Metsquerade, Komen Public Policy, Public Speaking, Metavivor where she was one of the faces of their newest campaigns and Komen. She's always looking for opportunities to educate and empower others to advocate for the best possible health care, You are worth all good things in this world! She believes in living life colorfully, full of adventure and with intention. All MBC patients should be able to create memories and meet important milestones in their lives which is only possible with research. Ashley continues to educate and remind others those living with MBC are not statistics or shells, but people. 116 People die a day with MBC , Stage 4 truly needs more funding. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/145602c5-52ce-4e94-bde5-e759f7e3ebc4/Marissa+Holzer+1.jpeg Episodes - Newly Diagnosed with MBC: Tests, Terms, & Tips with Dr. Rebecca Shatsky - Marissa Holzer Marissa is a 40-something "flattie" in sunny SoCal living with metastatic breast cancer (since March 2014), her boyfriend (and high school sweetheart), and her rescue schnauzer. She enjoys reading, stress baking, and roller skating. She is a Cure contributor and an advocate for aesthetic flat closure. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/a50f57c8-902c-4280-bcc0-479eef4e0499/Joan+Mancuso+1+%282%29.jpg Episodes - Newly Diagnosed with MBC: Tests, Terms, & Tips with Dr. Rebecca Shatsky - Joan Mancuso Joan has been living with metastatic breast cancer since 2007. She was originally diagnosed with early stage breast cancer in 2003. Her MBC presented as a lung metastasis and then again with a second lung metastasis and also a brain metastasis in 2008. She has been without any sign of MBC since 2008 and discontinued treatment in 2020 based on medical advice. For over a decade, Joan has been involved in many breast cancer projects. She is currently an advocate member of ASCO and a member of their TAPUR Publications Group, including a team to develop Plain Language Summaries for TAPUR reports. Joan is a co-author of ASCO’s recent update of its Policy Statement on Biosimilar and Interchangeable Products in Oncology. She has been a member of the planning committee and speaker at the Metastatic Breast Cancer Research Conference’s annual meeting as well as an advocate member of the Translational Breast Cancer Research Consortium with Abramson Cancer Center, University of Pennsylvania. The TBCRC develops and conducts phase II clinical trials. She is a consumer reviewer for the Department of Defense Breast Cancer Research Program and has been an advocate on many scientific grant proposals at major cancer centers. Through SHARE Cancer Support Joan has been interviewed on talk radio to raise MBC awareness during Breast Cancer Awareness Month. Joan stepped down from employment in 2009. She was a special reports editor on a news desk for financial news. Twitter: @2020VisionGirl https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/35fa6ef4-6a0a-4d33-b7ed-29ab8ca6fa9e/Sheila+Johnson+1+%282%29.jpeg Episodes - Newly Diagnosed with MBC: Tests, Terms, & Tips with Dr. Rebecca Shatsky - Sheila Johnson When it comes to health equity and breaking down systemic barriers to care in the metastatic breast cancer community, Sheila Johnson is an inspiration to us all. Not only has Sheila been living with metastatic breast cancer for 13 years, she is also a 25-year United States Air Force military veteran. With African American women dying 42% faster than any other race, Sheila has used her own experiences to enhance care for others and tackle this worrying statistic. Sheila is wholly committed to ensuring that not only is health equity awareness raised, but that people from marginalized and minority groups are included in conversations about their care. Sheila’s efforts are staggering and relentless. She has held positions as an ambassador, advocate and mentor with Living Beyond Breast Cancer, Young Women’s Initiative, National Breast Cancer Coalition, Shades of Brown Foundation, and The Metastatic Breast Cancer Project amongst others. Sheila is a Patient Insights Board member for Medidata bringing her voice to recruitment and inclusion of clinical trials to the African American community. She is also a Consumer Reviewer for METAvivor and the DOB Breast Cancer Research Program. Sheila exemplifies inclusion, and despite her own ongoing health issues, she has given her time selflessly to engage and include others. She has spearheaded projects that have served to enhance diversity and promote equality, including being part of the Susan G. Komen Advocates In Science Program and as a Komen Scholar. Sheila’s remarkable story has been featured online (https://www.storyhalftold.com/meet-sheila-mcglown) and in publications including The Breast Cancer Wellness Magazine Winter 2018 Edition “Ending Disparity”, and “O” The Oprah Magazine September 2020 Edition “An Air Force Vet’s Hardest Fight Yet.” Sheila is now a published author of “A Survivor’s Lens”, A Metastatic Breast Cancer Survivor’s Focus on Gods Word and Faith. Sheila’s resiliency and energy are contagious, and she delivers excellence in all aspects of her life, personal and professional. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/7dfda035-42a0-4629-b875-3b8795719a6c/Kelly+Shanahan+1.jpeg Episodes - Newly Diagnosed with MBC: Tests, Terms, & Tips with Dr. Rebecca Shatsky - Kelly Shanahan In 2008, Kelly had everything going for her: a busy and successful ob-gyn practice; a precocious 9 year old daughter; and a well used passport from traveling all over the world with her family to attend conferences, with a liberal dose of vacation on the side. When she was diagnosed with stage IIB breast cancer, she considered it a mere bump in the road. And for five years, breast cancer was an aside, something to put in the past medical history section of forms. Even when she developed sudden back pain, Kelly never thought it could be breast cancer rearing its ugly head – a pulled muscle, a herniated disc maybe, but not what it turned out to be: metastatic breast cancer in virtually every bone in her body, with a fractured vertebrae and an about to break left femur. Kelly was diagnosed in 2013, on her 53rd birthday. Neuropathy from the chemo cost her her career, but she has found a new purpose in advocacy. Kelly is on the board of METAvivor, a member of the Metastatic Breast Cancer Alliance, a Komen Advocate in Science, on the symptom intervention committee of the Alliance for Clinical Trials in Oncology, a grant reviewer and research advocate. She is passionate about getting patients to the table in the design, implementation, and follow up of clinical trials. Follow her on Twitter @stage4kelly. Kelly Shanahan is a mother, a wife, a daughter, a doctor, a woman LIVING with metastatic breast cancer. https://www.ourmbclife.org/episodes/newly-diagnosed-and-trailblazing monthly 0.5 2025-02-05 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/8598093a-84bc-4316-bc44-949251be0774/Michelle+Benjamin+2.JPG Episodes - Newly Diagnosed & Trailblazing: An Interview with Michelle Anderson-Benjamin - Michelle Anderson-Benjamin, MHA Michelle is a wife and mother of two from NYC. At the age 36 during the pandemic, Michelle was diagnosed with Stage-1 Triple Negative Breast Cancer and unfortunately at the age of 38 in 2022 her cancer returned and is now Stage IV. After being. diagnosed she realized the lack of representation for women of color in the cancer community and discovered For the Breast of Us on social media. Finally she found a community and became a Baddie Ambassador. She was inspired to turn her pain into her purpose and started The Fearless Warrior Project, LLC in 2021. As a Certified Mental Health Coach and Advocate and Healthcare Administrator her mission is to help individuals address and overcome their emotional and mental traumas and educate communities of color that in order to be a part of change we must be seated at tables where change happens. Michelle is currently in clinical trial for Stage IV TNBC and empower others about the importance of knowing all options of treatment. Michelle is superwoman with a Pink Cape! IG: @meamotorcycle, @fearlesswarriorprojectllc https://www.ourmbclife.org/episodes/newly-diagnosed-with-mbc-keeping-your-balance monthly 0.5 2025-02-05 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/d5cbb46f-ab8a-45ef-83ef-8424c58a96ff/Lisa+Nelson+1.jpg Episodes - Newly Diagnosed with MBC: Keeping Your Balance on the Emotional Rollercoaster - Lisa Petgrave-Nelson Lisa is a Licensed Master Social Worker, a Certified Oncology Social Worker, a trained End of Life Doula and an NYU Zelda Foster Leadership Fellow. She is also a student at Wurzweiler School of Social Work where she is currently pursuing her DSW degree, Doctorate in Social Work. She has worked in direct practice with chronically ill adults for over twenty years in settings that include Emory University Hospital, Cancer Treatment Centers of America, and The Cancer Institute at St. Francis Hospital. An invited presenter at a variety of venues educating professionals and social workers about issues related to grief and health disparities. These topics have been the focus of her research study entitled “COVID-19 Narratives: Stories from the Oncology Setting and many of her published articles and presentations including The Journal of End of Life & Palliative Care. Lisa remains an ardent advocate for healthcare equity especially for those in under-served communities. IG : @diaryofablacksocialworker https://www.ourmbclife.org/episodes/meditation-mondays-1 monthly 0.5 2024-02-09 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/333e3445-e6bf-44cd-98d6-ca4094ba7a5b/Barbara+Chutroo+2.jpeg Episodes - Episode 1: Meditation Mondays with Barbara Chutroo - Barbara Chutroo Barbara Chutroo has made use of SHARE’s services since her first diagnosis in 2015 and is eternally grateful for all the support she has received. She is a clinical social worker and movement therapist who worked with severe and persistent mental illness in the South Bronx for thirteen years. She also taught psychology and child development at NYC College of Technology. She is especially interested in the integration of body and mind, an investigation she makes use of in her meditation practice. She began to study zen as an undergraduate in 1976 and has continued since then to explore various different meditation practices. The meditation community has provided her with valuable guiding principles for her life and personal growth. She was born and raised in New York City where she lives with her husband and two rescue cats. https://www.ourmbclife.org/episodes/mbc-advocacy-finding-purpose-in-adversity monthly 0.5 2025-02-05 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/324399ab-d75c-437e-8efe-035e5118dc8a/Abigail+Johnston+1.jpg Episodes - MBC Advocacy: Finding Purpose in Adversity - Abigail Johnston Abigail is a recovering lawyer living in Orlando, Florida with her husband, two boys and a very spoiled cat. She has been living with Stage IV Metastatic Breast Cancer since 2017 and has found a tremendous sense of purpose through advocacy. Abigail serves as the Director of Mentorship for Project Life, as the Chair of the MBC Leadership Committee for Surviving Breast Cancer, as a research advocate with FORCE, as a RISE Legacy advocate for Young Survival Coalition, moderates an MBC support group with the 305PinkPack and a volunteer with a variety of organizations focused on serving the breast cancer and the MBC community. You can find her musings online at No Half Measures and on quite a few social media platforms. You can contact her at: StageIVAdvocacyAMJ@gmail.com & mentorship@projectlifembc.com IG: @amj1315 FB: Abigail Schroeder Johnston Twitter: @amjohnston1315 LinkedIn: Abigail Johnston https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/f3983e6f-098c-40ee-a2e8-fdeb33f8487f/Copy+of+Copy+of+Lesley+Glenn+1.jpeg Episodes - MBC Advocacy: Finding Purpose in Adversity - Lesley Glenn Passion, motivation and personal experience of living with Metastatic Breast Cancer for the past 10.5 years is what drives Lesley’s desire to be an advocate. Her goal is to partner with communities, researchers and organizations to aid with the funding of research, raising awareness, and providing support to the overlooked community of those who also live with Metastatic Breast Cancer. With a bachelors of Science in Organizational Leadership, she has been actively involved in advocacy since 2015, training with the inaugural Hear My Voice Volunteer class presented by Living Beyond Breast Cancer. She was invited back as a mentor in 2018 and was awarded the Living Beyond Breast Cancer Leadership Volunteer Award in the Fall of the same year. She enjoys working with researchers and other stakeholders in the MBC field. She is a member of the Metastatic Breast Cancer Alliance, Susan G. Komen’s Advocates in Science, the scientific advisory committee for the Love Research Army, and a consumer reviewer with the DOD-CDMRP, PICORI and Komen. She recently launched her biggest endeavor, Project Life, a virtual wellness house for those living with MBC and their loved ones. Lesley currently lives in the Rogue Valley of Southern Oregon with her rescue pup and 2 rescue cats. You can contact her at: Lesley@projectlifembc.com IG & Twitter: @projectlifembc https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/5846ec47-5cb4-4bd0-a734-61722eff86ed/Cathy+Ormerod+1.jpg Episodes - MBC Advocacy: Finding Purpose in Adversity - Catherine Ormerod , MSS, MSLP, Executive Vice President of Strategy & Mission for Living Beyond Breast Cancer Education. Advocacy. Collaboration. Support. These four words summarize Cathy’s background and expertise. She employs each to fuel the LBBC staff and board to create programs that provide practical information, comfort, and insight into how to make sense of a disease that profoundly alters people’s lives and sense of self. She raises dollars, helps develop new programs, and brokers partnerships with people and organizations that expand LBBC’s expertise. Primarily, she promotes LBBC’s services to anyone who will listen. LBBC’s Leadership Volunteers carry the organization’s mission into their communities, whether online or in-person, these volunteers are found in communities across the country advocating for better — for better treatments, wider diversity in clinical trials, more leadership opportunities in health organizations, health equity, access to treatments, fiscal sanity when it comes to cancer costs, and for mental health services. Prior to joining LBBC, Cathy served as the director of national programs of VISION 2020, a national program of the Institute for Women’s Health and Leadership at Drexel University’s College of Medicine. She was also the founding director of the Nonprofit Executive Leadership Institute at Bryn Mawr College Graduate School of Social Work and Social Research, which provides executive education to build skills of nonprofit leaders while providing them with a network of their peers. You can contact her at: cormerod@lbbc.org IG & Twitter: @LivingBeyondBC FB & LinkedIn: LivingBeyondBreastCancer IG: @clormerod FB & Twitter: cormerod LinkedIn: CatherineOmermod https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/ef24599c-eb6f-4f84-aba7-26c8d3133396/Dan+Cramer+1.jpg Episodes - MBC Advocacy: Finding Purpose in Adversity - Dan Cramer Dan (he/him/his) is the Co-founder of Grassroots Solutions, a consulting firm that advises campaigns, advocacy organizations and foundations on purposeful engagement and advocacy for the public good. Prior to his time as a coach and consultant, Dan managed political campaigns, served on the staff of both state and federal elected officials and earned a J.D. from Georgetown University Law Center. Dan and his wife Cassie are also cancer bloggers chronicling their efforts to navigate life as a couple after her Metastatic Breast Cancer diagnosis. You can see their reflections at Meaning and Stuff. Dan also serves on the board of METAvivor and chairs the organization’s Advocacy Committee You can contact him at: Dan@metavivor.org IG: @dancramer402 LinkedIn: DanielCramer https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/9fb2f931-44af-47df-a537-c4dce892e5c1/Tami+Bowling+1.jpg Episodes - MBC Advocacy: Finding Purpose in Adversity - Tami Eagle Bowling Tami is the Founder and Creator of The Eagle Method, a framework for learning to effectively build resilience and embrace uncertainty, so that people can thrive at home and at work. With no family history at the age of 41, she was diagnosed with metastatic breast cancer (MBC), otherwise known as Stage IV breast cancer, which is considered terminal. She had to adapt to this unexpected bombshell in her life when her children were just 2 and 4 years old. Tami generously donates her time to volunteer for organizations that raise funds for MBC research and mentors the newly diagnosed. She is the Global Campaign Director of #LightUpMBC, an annual campaign that shines a light on the disease. Tami is passionate about inspiring others and enjoys sharing her insights on embracing uncertainty. Her message of resilience and passion for life resonates loud and clear to all who hear her speak. You can contact her at: lightupmbc.campaigndirector@gmail.com FB, IG & Twitter: @LightUpMBC IG: @EagleMethod FB: @TamiEagleBowling https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/5c4bfb86-3b96-4363-87b0-960f4950d5e5/Amy+Bruemer+1.jpeg Episodes - MBC Advocacy: Finding Purpose in Adversity - Dr. Amy Beumer Amy was diagnosed with stage I breast cancer in 2017 and metastatic in 2020. In her previous life she was a biology professor teaching various microbiology and introductory biology courses as well as conducting research in drinking water microbiology and team learning. Currently, she is upping her knowledge of cancer research, advocating, and getting as much traveling, hiking, reading, gardening and time with friends and family in as possible. Her current advocacy focuses on peer support and mentoring as well as research advocacy. You can contact her at: beumerae@gmail.com IG: @amybeumer https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/91441b54-a79c-4b8b-a16b-58cdf4a45f2c/Janice+Cowden+1.jpeg Episodes - MBC Advocacy: Finding Purpose in Adversity - Janice Cowden, RN Janice is a metastatic breast cancer patient and a strong advocate and proponent for increased knowledge about disease, treatments, and clinical trials for patients. Originally diagnosed in 2011 with triple negative, her cancer metastasized in 2016. Janice's background as a pediatric nurse drove her to learn more about the science behind her disease and available treatment options. Janice is a graduate of the Living Beyond Breast Cancer (LBBC) Hear my Voice program as well as a graduate of the National Breast Cancer Coalition’s (NBCC) Project LEAD program. Janice served as a mentor at the inaugural launch of the GRASPCancer project (Guiding Researchers And Advocates To Scientific Relationships). And she served as a Grad Alumni mentor for the 2018 LBBC Hear My Voice participants. She is also a trained LBBC volunteer for their Peer-Matched Helpline, and a Peer Support Leader for METAvivor Research and Support, Inc. In her spare time, Janice enjoys traveling, reading fiction, swimming, spending time with family and friends. She and her husband of 41 years have two adult children and three grandchildren, ages 3, 4, and 5. You can contact her at: JaniceC8957@aol.com IG & Twitter: @janiceTNBCmets FB: Janice Cowden LinkedIn: Janice Cowden https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/2c76b6e7-9baa-4906-b58e-6123e88a574c/Stephanie+Walker.jpg Episodes - MBC Advocacy: Finding Purpose in Adversity - Stephanie Walker, RN Stephanie is registered nurse with close to 40 years of clinical practice and secondary teaching experience. She has spent time in pediatric and adult critical care, working in such areas as Level 1 trauma centers and critical access hospitals. Stephanie’s last 15 years of nursing focused on end of life/hospice care. In 2015, she received a de novo metastatic breast cancer diagnosis, and 3 years later she began her path into MBC advocacy. She has pushed for rural equality and equity in breast cancer. She is a member of the MBC Alliance, Project lead on the BECOME initiative (Black Experience of Clinical Trial and Opportunities for Meaningful Engagement), an LBBC Helpline/HMV volunteer and a Susan G Komen volunteer. Stephanie is married and lives in Tarboro, NC with her husband John and their rescue dog Rex, advocating for men and women in rural areas as her own, for equal access to quality healthcare, treatment modalities, and resources. You can contact her at: StephanieWalker1303@gmail.com IG: @stepnyrn Twitter: @faceofstage4 LinkedIn: Stephanie Walker https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/33786ccb-4bc8-445a-bd5d-4270d54ea048/Rosemary+Carrera+1.jpg Episodes - MBC Advocacy: Finding Purpose in Adversity - Dr. Rosemary Carrera Rosemary is founder of 305 Pink Pack, a Miami-based non-profit that provides vital direct and support services for local women in cancer treatment. She was diagnosed with breast cancer at the age of 40, and was blessed to have her family and loved ones support her, her husband, Oscar, and their daughter, Alessi, who was only 8 months old at the time. Seeing women with limited resources struggle through treatment, prompted Rosemary to create 305 Pink Pack which ensures that local women can access their treatment, and recover from it, by offering transportation, child-care, support services and more. You can contact her at: Rosemary@305PinkPack.org @305pinkpack on All Platforms https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/e122b5f9-f92c-44cb-a9e6-d35e375a50c4/Miranda+Gonzales.jpg Episodes - MBC Advocacy: Finding Purpose in Adversity - Miranda Gonzales Miranda was a stay-at-home mom to her family of 7 when she received her Stage III diagnosis in 2016. As a young Latina, she often felt out of place among the other cancer patients. Needing to connect with others like her put her on a path to learning to provide that very support to others that she had always wanted. Miranda began to shift her volunteerism from school activities to the breast cancer community. She participates in all facets of advocacy - she is a CanCare peer support volunteer, a YSC RISE Advocate, a Young Advocate with Living Beyond Breast Cancer, and an Ambassador with For The Breast of Us, to name a few. Miranda then began to see the division between “early-stagers” and the MBC community. Bridging this gap and providing education on MBC to other early-stagers has become a big focus of her advocacy. Miranda currently works for SHARE Cancer Support, behind the scenes for the Our MBC Life podcast from her home in Houston, Texas. She is truly honored to be able to work alongside some amazingly talented and resilient women. You can contact her at: MirandaLDGonzales@gmail.com IG: @MirLorDehGon https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/dde04fee-33c7-43f7-8b3b-fc78237949fc/Rod+Ritchie+1.png Episodes - MBC Advocacy: Finding Purpose in Adversity - Rod Ritchie Rod is a Sydney-born writer, internet publisher, and breast cancer patient activist, diagnosed in March 2014 with Stage IIIB IBC. Two years later he was diagnosed with prostate cancer. Currently he’s NED for both cancers. A regular poster on Twitter @malefitness, he contributes to various closed breast and prostate cancer Facebook pages, writes articles and creates videos. His website, Male Breast Cancer, includes links to the latest research. Project LEAD Graduate 2018 Patient Advocate scholarship to San Antonio Breast Cancer Symposium, 2019 President, Male Breast Cancer Global Alliance You can contact him at: RodneyRitchie@gmail.com Twitter: @malefitness https://www.ourmbclife.org/episodes/2022-in-review-best-in-mbc-with-dr-erika-hamilton monthly 0.5 2025-02-05 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/3357140b-3d6f-4e0e-96b6-e06d29fb30e8/Erika+Hamilton+1.jpg Episodes - 2022 in Review: Best in MBC with Dr. Erika Hamilton - Make it stand out Erika P. Hamilton, MD Director, Breast Cancer and Gynecologic Cancer Research, Sarah Cannon Research Institute https://www.ourmbclife.org/episodes/livingbeyondbreastcancer-silent-voices-no-longer monthly 0.5 2025-03-28 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/7af17719-c431-412d-81d4-050183c9a2e6/Jean+Sachs+1.jpg Episodes - LBBC - Silent Voices No Longer - Jean Sachs MSS, MLSP, Chief Executive Officer, LBBC Jean Sachs, MSS, MLSP https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/99aa39d2-2ae2-48a6-8363-00f4402bdb3b/Kate+Pfitzer+1.jpg Episodes - LBBC - Silent Voices No Longer - Kate Pfitzer, Director of MBC Programming, SHARE Since 2019 Kathleen has been actively involved with advocacy as a Metastatic Breast Cancer peer volunteer at SHARE Cancer Support. She began her volunteer work as a dedicated MBC helpline volunteer and MBC peer then added support group facilitator as well as OUR MBC Life podcast host and producer to her roles. Kate believes there is nothing better than being surrounded by peers “who get it.” She feels strongly that no-one with MBC should feel alone and everyone should have access to support. Kate is passionate about the needs of the community and strives to educate and empower people to advocate for the best possible care and quality of life. Kate recently accepted a position of Director of Metastatic Breast Cancer Program at SHARE Cancer Support. She is excited to use her science background as well as her MBC patient experience to continue the success of the metastatic breast cancer programs and is committed to developing new programs with the goal of improving patient experience and survivorship. Kate graduated with honors and earned a Master of Science degree in Healthcare Policy and Management, Community Health Education and Planning, an Advanced Certificate in Healthcare Management, and a Bachelor of Science degree in Occupational Therapy. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/bb02542b-6cfa-4c3d-aede-b03951c751f0/Terlisa+Sheppard+1.jpg Episodes - LBBC - Silent Voices No Longer - Terlisa Sheppard Terlisa is a 4-time breast cancer survivor of 24 years. She was originally diagnosed in November 1998, with stage III, (HER2+, ER+, PR+), breast cancer at the age of 31 years old, and while 8 ½ months pregnant with her second child. She has been living with stage IV metastatic breast cancer for 21 years and has had metastases to her bones, lungs, liver, spine, abdomen, and brain. Terlisa is the mother of two beautiful daughters, who continue to give her strength and the daily motivation that she needs to get through each day, no matter how hard it might seem at the moment. She is a patient advocate and a fighter, not only for herself, but for those who share her similar fate. Her advocacy involvement includes one-on-one mentoring with breast cancer patients and their families, by spreading hope and compassion through their diagnosis. She continues to spend countless hours volunteering and raising awareness for the need for more funding of metastatic breast cancer research. Through her very own journey, she has inspired others to fight through their diagnosis and live their best life, moment by moment. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/e35cc6cc-0d3d-467e-ba41-57a191d2fe60/Stephanie+Walker.jpg Episodes - LBBC - Silent Voices No Longer - Stephanie Walker, RN Diagnosed in July 2015 with de novo MBC. A Registered Nurse with close to 40 years of clinical practice and secondary teaching experience. Her experience has been pediatric and adult critical care working in level 1 trauma centers to critical access hospitals. The last 15 years of nursing was with End of Life/Hospice care. Only aware of MBC advocacy 3 years after diagnosis, she has pushed for rural equality, equity in breast cancer. She is a member of MBC Alliance (in which she is project lead on the BECOME initiative (Black Experience of Clinical Trial and Opportunities for Meaningful Engagement ), LBBC Helpline/HMV volunteer and SG Komen volunteer. She is married and lives in Tarboro NC with husband John and rescue dog Rex, advocating for men and women in rural areas as my own for equal access to quality healthcare , treatment modalities, and resources keeps her busy . https://www.ourmbclife.org/episodes/meditation-mindfulness-and-mbc-finding-your-inner-calm monthly 0.5 2025-02-05 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/3b13c4c5-880e-480a-8064-481186323365/April+Pichon+1a.jpg Episodes - Meditation, Mindfulness, and MBC: Finding Your Inner Calm - April Pichon April Pichon, MBA, LCSW-S, OSW-C is a licensed clinical social worker and member of the cancer care team at Houston Methodist Hospital Medical Center. She has been a social worker for nearly 17 years and has spent most of her career assisting cancer patients and their families. She has worked at MD Anderson Cancer Center and Houston Methodist Baytown Cancer Center where she helped patients with a multitude of psychosocial needs related to treatment. She also has experience providing counseling to patients with chronic illness and has trained in Motivational Interviewing (MI) and Cognitive Behavioral Therapy (CBT). She is a member of both the Association of Oncology Social Work (AOSW) and the National Association of Social Workers (NASW). She is also a certified oncology social worker (OSW-C). April is passionate about working with oncology patients and their families and being a resource to them during such a life changing experience. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/333e3445-e6bf-44cd-98d6-ca4094ba7a5b/Barbara+Chutroo+2.jpeg Episodes - Meditation, Mindfulness, and MBC: Finding Your Inner Calm - Barbara Chutroo Barbara Chutroo has made use of SHARE’s services since her first diagnosis in 2015 and is eternally grateful for all the support she has received. She is a clinical social worker and movement therapist who worked with severe and persistent mental illness in the South Bronx for thirteen years. She also taught psychology and child development at NYC College of Technology. She is especially interested in the integration of body and mind, an investigation she makes use of in her meditation practice. She began to study zen as an undergraduate in 1976 and has continued since then to explore various different meditation practices. The meditation community has provided her with valuable guiding principles for her life and personal growth. She was born and raised in New York City where she lives with her husband and two rescue cats. https://www.ourmbclife.org/episodes/laughter-as-medicine monthly 0.5 2025-09-11 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/b2fd4f7f-7db1-45c7-975a-61cee36c3f33/KHEVIN+BARNES..jpeg Episodes - Laughter as Medicine - Khevin Barnes Male Breast Cancer Survivor/Advocate, Health Journalist, Laughter Yoga Teacher, Professional Magician, Musician Khevin is a regular contributing writer for CURE MAGAZINE, a certified Laughter Yoga Teacher and the co-founder of “Laughter Yoga USA”. He wrote and composed a stage musical called “Sons of Saint Agatha”, a dark comedy promoting Male Breast Cancer awareness. www.LaughterYogaUSA.com www.LaughterYogaOnThePhone.com https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1b1e5352-a24a-4938-8173-8546d55fcb92/IMG_20220903_120659340+%282%29.jpg Episodes - Laughter as Medicine - Elaine Price-Lockridge Elaine is a recent student of Tony Vicich’s comedy course at Tempe Center for the Arts. Originally from the L.A. area of California, she’s been living in Phoenix for 29 years. She is currently attending open mic nights at local bars and her comedy covers her life’s experiences with becoming single at 49, life with her “Gusband” (aka gay bestie) and finding humor and joy as she lives with Stage IV Metastatic Breast Cancer. When she’s not making people laugh she can be found at art groups, writing groups, comedy clubs, film festivals, traveling and countless happy hours. IG: @lainbee2. Cancer Support Community Arizona www.cscaz.org https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/ea4278e3-e8bc-4e57-9b88-d53943854a21/Jenny+Saldana+2.jpg Episodes - Laughter as Medicine - Jenny Saldana Actor, Comedian, & Writer Dominicana Jenny grew up the child of immigrants in Washington Heights, New York. Her mother cleaned houses and her father worked at a gas station to make a better life for Jenny and her sister, Jenniffer (yes, they are Jenny and Jenniffer - we’re the Dominican George Foreman’s). When Jenny was high school age the family moved to Miami, Florida where she attended Miami Senior High and met her friend, drama teacher and mentor, Marty Hancock. Marty encouraged Jenny to continue her love of theatre, leading to Jenny applying and being accepted to the University of Pittsburgh where she graduated with a BA in Theatre Arts. She soon returned to her beloved New York City after college to pursue her dreams. In 2001, she grew tired of just getting background acting work, in particular relevant material for Latinas. She wrote her first play, Dancing In The Mirror, a collection of monologues, modeled after John Leguizamo’s Mambo Mouth. It was produced by NBC and directed by Maria Escobedo in NYC. At the 2003 National Latino Playwright Festival, Dancing In The Mirror won a main stage production. In 2006, at the age of 34, Jenny heard the words that would change her life forever: “I’m sorry, but this is breast cancer.” Her treatment included a right-side mastectomy and reconstruction, followed by chemo. During this time, Jenny wrote her next play, PINK: The Chronicles of BC Jenny. PINK was produced and directed by Linda Nieves-Powell and Latino Flavored Productions at the legendary Nuyorican Poets Café. PINK then toured colleges, bringing breast cancer awareness nation-wide. In 2008, PINK won 3rd place in the MetLife Nuestras Voces National Playwriting Contest. With Latino Flavored productions, Jenny also starred in Yo Soy Latina and Jose Can Speak. Her third play, Please Hold was a mainstage feature at The Latina Theatre Festival in 2009. Five years after having a mastectomy, yet still ‘too young’ for a mammogram (thanks American health care system!) Jenny decided to pay it forward and became the peer breast cancer counselor at New York Presbyterian Hospital and began what her father lovingly calls her ‘ministry’ of being there for the next person beginning their cancer journey. After 11 years at NYPH, Jenny took another leap of faith and decided to quit the hospital to act and write full time. She co-starred with Sacha Baron Cohen in The Dictator and has been a guest star on: Bull, Blue Bloods, Search Party, New Amsterdam, and High Maintenance to name a few. In her comedy career, Jenny has opened and worked along comedy greats such as: Marina Franklin, Jim Gaffigan, Mark Viera, Keith Robinson, Pat Brown, and many more. Her latest play, A Desperate Digital Dating Diary is her love letter to ‘Latinaness’ and all women who have ever swiped right. And to top off everything Jenny has achieved in her career, she even once baked a delicious pie. FB: Jenny L. Saldaña Twitter: TheLBGirlShow IG: LittleBrownGirlShow https://www.ourmbclife.org/episodes/systemic-racism-and-mbc-in-clinical-trials monthly 0.5 2025-02-05 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/51d08381-a810-4861-9312-a81e54941097/Stephanie+Walker.jpg Episodes - Systemic Racism and MBC in Clinical Trials - Make it stand out Stephanie Walker, RN https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/be452539-021d-44ca-8ca8-750c42dbbf7d/IMG_0186copy.jpeg Episodes - Systemic Racism and MBC in Clinical Trials - Make it stand out Reverend Tawana Davis, Ph.D. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/e0c3018d-b4c0-4a25-91aa-5a3c4de091e3/Valarie+Worthy+2.jpg Episodes - Systemic Racism and MBC in Clinical Trials - Make it stand out Valarie Worthy, MSN, RN https://www.ourmbclife.org/episodes/when-the-dust-settles-part-two monthly 0.5 2025-02-05 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/b52ad4da-b1ab-4465-8d88-790951724214/Screen+Shot+2022-11-22+at+10.34.48+PM.png Episodes - ASCO 2022: When The Dust Settles, What Are My Treatment Options For ER+/HER2- MBC? - Make it stand out https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313476/ https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/60b31f13-3d6d-4c46-ac3a-e791db5c3e8b/Screen+Shot+2022-11-22+at+10.28.12+PM.png Episodes - ASCO 2022: When The Dust Settles, What Are My Treatment Options For ER+/HER2- MBC? - Make it stand out Overview of the clinical trials for the approved CDK4/6 inhibitors in the metastatic setting. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/35a3a183-18c5-4f98-9aaf-0b15ebe7dfae/Screen+Shot+2022-11-22+at+10.31.41+PM.png Episodes - ASCO 2022: When The Dust Settles, What Are My Treatment Options For ER+/HER2- MBC? - Make it stand out Clinical Activity of the CDK4/6 inhibitors in different clinical settings. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/7fb76764-8165-42d7-89e3-f0f8db2760e5/Dr.+Sara+Hurvitz.jpg Episodes - ASCO 2022: When The Dust Settles, What Are My Treatment Options For ER+/HER2- MBC? - Sara Hurvitz, MD, FACP Dr. Hurvitz is an associate professor at the David Geffen School of Medicine at UCLA; medical director of the Jonsson Comprehensive Cancer Center Clinical Research Unit; co-director of the Santa Monica-UCLA Outpatient Oncology Practices; and director of the Breast Cancer Clinical Trials Program at UCLA. She is also a member of the American Society of Clinical Oncology and the American Association of Cancer Research, and is a fellow of the American College of Physicians. Dr. Sara Hurvitz is a medical oncologist who specializes in the treatment of women with breast cancer, and is involved in designing, implementing and leading national and international clinical trials to test new targeted therapies. She is board certified in internal medicine and medical oncology. Dr. Hurvitz maintains a robust clinical and translational research portfolio, for which she has won numerous awards over the years, including the Marni Levine Memorial Breast Cancer Research Award in years between 2008 and 2015. She currently leads the Translation Oncology Research Laboratory at UCLA in the preclinical evaluation of novel breast cancer targets. Dr. Hurvitz earned her medical degree from the University of Southern California School of Medicine. She then completed her internal medicine residency at UCLA, serving as chief resident, followed by her hematology/oncology fellowship at UCLA. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/4a874f23-169f-4b25-bfa9-e7582b223b6f/Dr.+Kevin+Kalinsky+1+%283%29.jpg Episodes - ASCO 2022: When The Dust Settles, What Are My Treatment Options For ER+/HER2- MBC? - Kevin Kalinsky, MD, MS Dr. Kalinsky is an Associate Professor in the Department of Hematology and Medical Oncology at Emory University School of Medicine. He serves as the director of the Glenn Family Breast Center at Winship where he is tasked with fulfilling the vision to improve breast cancer outcomes by aligning research and education with cancer treatment and prevention. Dr. Kalinsky received his medical degree from the Medical University of South Carolina and a Masters in Biostatistics, Patient Oriented Research Track from Columbia University Mailman School of Public Health. His training included a Residency and Medical Oncology Fellowship at Tufts-New England Medical Center, Breast Cancer Research Fellowship at Massachusetts General Hospital, and Breast Cancer Advanced Oncology Fellowship at Memorial Sloan-Kettering Cancer Center. Dr. Kalinsky's research involves the development of early-phase clinical trials to assess novel therapeutics in breast cancer based on tumor genomics. He has received the NCI Cancer Clinical Investigator Team Leadership Award, Physician of Impact Award by Komen Greater NYC, Ewig Clinical Scholar Teaching Award, and SWOG Career Engagement Award. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/f4cd790f-77b0-40ab-8523-9b3f0247b748/Dr.+Stephanie+Graff+2.jpg Episodes - ASCO 2022: When The Dust Settles, What Are My Treatment Options For ER+/HER2- MBC? - Stephanie Lynn Graff, MD, FACP Dr. Graff is the Director of Breast Oncology at Lifespan Cancer Institute at the Legorreta Cancer Center at Brown University in Providence, Rhode Island. Dr. Graff serves as co-lead of the Breast Cancer Translational Research Disease Working Group at Brown University and is an Assistant Professor of Medicine at the Warren-Alpert School of Medicine. In Dr. Graff is a medical advisor to the Dr. Susan Love Foundation for Breast Cancer Research. Dr. Graff is board certified in Medical Oncology, Hematology, and Internal Medicine; and completed a breast oncology sub-fellowship at the University of Kansas. Dr. Graff is a PI on numerous clinical trials in addition to her work in translational research, genomics, and gender bias. She is an award-winning writer, social media influencer, and sought-after public speaker. Dr. Graff has received the Frist Humanitarian Award for her work in the community and the Benjamin L. Sapers Memorial Award for her “passion for pedagogy, academic rigor, empathy and humanism, with profound feeling for the person as patient.” Ultimately, Dr. Graff is passionate about connecting with her patients to provide personalized, comprehensive oncology care, advancing breast cancer research, and breast cancer prevention. Growing up in a small farming community in rural Missouri, Stephanie Lynn Graff, MD, FACP was the first in her family to attend college. Because she was drawn to science from a young age, she enrolled in a 6-year medical program right out of high school. As she progressed from medical school to residency to a fellowship, she was fascinated by every aspect of the science of oncology—including cell biology and pharmacology. Dr. Stephanie Graff is the Director of Breast Oncology at Lifespan Cancer Institute at the Legorreta Cancer Center at Brown University in Providence, Rhode Island. Dr. Graff serves as co-lead of the Breast Cancer Translational Research Disease Working Group at Brown University and is an Assistant Professor of Medicine at the Warren-Alpert School of Medicine. Prior to joining the team at Lifespan/Brown, she was Director of both the Breast Program and Clinical Research at the Sarah Cannon Cancer Institute at HCA Midwest, as well as Associate Director of the Breast Cancer Research Program at Sarah Cannon Research Institute and National Breast Lead for the Sarah Cannon Cancer Network’s clinical programs. In addition, Dr. Graff serves as a medical advisor to the Dr. Susan Love Foundation for Breast Cancer Research. Dr. Graff is board certified in Medical Oncology, Hematology, and Internal Medicine; and completed a breast oncology sub-fellowship at the University of Kansas. Dr. Graff has broad experience as a Principal Investigator on numerous clinical trials across all phases of drug development, in addition to work in translational research, genomics, and gender bias. In addition to scientific publications, she is an award-winning writer, social media influencer, and sought-after public speaker. Dr. Graff has received the Frist Humanitarian Award for her work in the community and the Benjamin L. Sapers Memorial Award for her “passion for pedagogy, academic rigor, empathy and humanism, with profound feeling for the person as patient.” Dr. Graff currently serves on the American Cancer Society Rhode Island Leadership Council and actively volunteers in the American Society of Clinical Oncology, where she is a 2020 graduate of the prestigious ASCO Leadership Development Program, and now serves on the Joint Certifications Committee and Women In Oncology Work Group. Ultimately, Dr. Graff is passionate about connecting with her patients to provide personalized, comprehensive oncology care, advancing breast cancer research, and breast cancer prevention. https://www.ourmbclife.org/episodes/fes-cerianna-screening-for-estrogen-positive-mbc monthly 0.5 2025-02-05 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/52ac1446-591c-4290-ba8f-cf66e08894aa/cerianna+map.png Episodes - RTAC: FES/Cerianna Screening for Estrogen Positive MBC - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/5736dffd-f788-4c4e-bd5b-b33e7bbd71b1/PamkohlPhoto1.jpg Episodes - RTAC: FES/Cerianna Screening for Estrogen Positive MBC - Make it stand out Pam Kohl https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/bf8e58b8-0bce-4415-b963-d33058077b29/Dr.+Hannah+Linden.jpg Episodes - RTAC: FES/Cerianna Screening for Estrogen Positive MBC - Make it stand out Hannah M Linden MD FACP https://www.ourmbclife.org/episodes/caregivers-we-cant-do-this-without-you monthly 0.5 2025-02-05 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1667836698544-AHIDU5JIJ7QJ0V0JDXGN/Danny+Green+3.jpeg Episodes - Caregivers: We Can’t Do This Without You! https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1667836720687-6C9ZO72EB1697RVHTDKG/Danny+Green+2.jpg Episodes - Caregivers: We Can’t Do This Without You! https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1667316049566-8UW8BDLKUQABJHV7E5Z5/Caregivers+Kayla+2.jpeg Episodes - Caregivers: We Can’t Do This Without You! https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1667316053545-E785ONXPS2OFI8PJ76ZB/Caregivers+Kayla+%26+Steph.jpeg Episodes - Caregivers: We Can’t Do This Without You! https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1667315725851-0BCL2IQYM5A2Y27KDK7U/William+Roth+1.jpg Episodes - Caregivers: We Can’t Do This Without You! https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1667315783987-58N96NU7GUIXJIF09D1A/Andrea+Roth.png Episodes - Caregivers: We Can’t Do This Without You! https://www.ourmbclife.org/episodes/when-the-dust-settles monthly 0.5 2025-02-05 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/f4cd790f-77b0-40ab-8523-9b3f0247b748/Dr.+Stephanie+Graff+2.jpg Episodes - ASCO 2022: When the Dust Settles, Will ADCs Change MBC? - Stephanie Lynn Graff, MD, FACP Dr. Graff is the Director of Breast Oncology at Lifespan Cancer Institute at the Legorreta Cancer Center at Brown University in Providence, Rhode Island. Dr. Graff serves as co-lead of the Breast Cancer Translational Research Disease Working Group at Brown University and is an Assistant Professor of Medicine at the Warren-Alpert School of Medicine. In Dr. Graff is a medical advisor to the Dr. Susan Love Foundation for Breast Cancer Research. Dr. Graff is board certified in Medical Oncology, Hematology, and Internal Medicine; and completed a breast oncology sub-fellowship at the University of Kansas. Dr. Graff is a PI on numerous clinical trials in addition to her work in translational research, genomics, and gender bias. She is an award-winning writer, social media influencer, and sought-after public speaker. Dr. Graff has received the Frist Humanitarian Award for her work in the community and the Benjamin L. Sapers Memorial Award for her “passion for pedagogy, academic rigor, empathy and humanism, with profound feeling for the person as patient.” Ultimately, Dr. Graff is passionate about connecting with her patients to provide personalized, comprehensive oncology care, advancing breast cancer research, and breast cancer prevention. Growing up in a small farming community in rural Missouri, Stephanie Lynn Graff, MD, FACP was the first in her family to attend college. Because she was drawn to science from a young age, she enrolled in a 6-year medical program right out of high school. As she progressed from medical school to residency to a fellowship, she was fascinated by every aspect of the science of oncology—including cell biology and pharmacology. Dr. Stephanie Graff is the Director of Breast Oncology at Lifespan Cancer Institute at the Legorreta Cancer Center at Brown University in Providence, Rhode Island. Dr. Graff serves as co-lead of the Breast Cancer Translational Research Disease Working Group at Brown University and is an Assistant Professor of Medicine at the Warren-Alpert School of Medicine. Prior to joining the team at Lifespan/Brown, she was Director of both the Breast Program and Clinical Research at the Sarah Cannon Cancer Institute at HCA Midwest, as well as Associate Director of the Breast Cancer Research Program at Sarah Cannon Research Institute and National Breast Lead for the Sarah Cannon Cancer Network’s clinical programs. In addition, Dr. Graff serves as a medical advisor to the Dr. Susan Love Foundation for Breast Cancer Research. Dr. Graff is board certified in Medical Oncology, Hematology, and Internal Medicine; and completed a breast oncology sub-fellowship at the University of Kansas. Dr. Graff has broad experience as a Principal Investigator on numerous clinical trials across all phases of drug development, in addition to work in translational research, genomics, and gender bias. In addition to scientific publications, she is an award-winning writer, social media influencer, and sought-after public speaker. Dr. Graff has received the Frist Humanitarian Award for her work in the community and the Benjamin L. Sapers Memorial Award for her “passion for pedagogy, academic rigor, empathy and humanism, with profound feeling for the person as patient.” Dr. Graff currently serves on the American Cancer Society Rhode Island Leadership Council and actively volunteers in the American Society of Clinical Oncology, where she is a 2020 graduate of the prestigious ASCO Leadership Development Program, and now serves on the Joint Certifications Committee and Women In Oncology Work Group. Ultimately, Dr. Graff is passionate about connecting with her patients to provide personalized, comprehensive oncology care, advancing breast cancer research, and breast cancer prevention. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/d5cc1a31-d686-4d72-9a19-56da1104978f/Dr.+Hope+Rugo+1.png Episodes - ASCO 2022: When the Dust Settles, Will ADCs Change MBC? - Hope S. Rugo, MD, FASCO Dr. Rugo is a medical oncologist and hematologist specializing in breast cancer research and treatment. A Professor of Medicine, Dr. Rugo joined the Breast Care Center in 1999 after a decade of experience at University of California San Francisco (UCSF) in malignant hematology and bone marrow transplantation for a variety of diseases, including breast cancer. She entered the field of breast cancer in order to incorporate novel therapies based on an understanding of the biology of cancer with excellent quality of care into the treatment of women with breast cancer. Dr. Rugo is the Director of Breast Oncology and Clinical Trials Education at the UCSF Helen Diller Family Comprehensive Cancer Center. She is a principal investigator of multiple clinical trials focusing on combining novel targeted therapeutics with standard treatment to improve the treatment of both early and late stage breast cancer and has published widely in this area. Her current research interests include immunotherapy and combinations of targeted agents in the treatment of breast cancer to overcome resistance. In addition, Dr. Rugo has conducted a number of studies focusing on reducing toxicity from therapy, resulting in approval of scalp cooling to reduce chemotherapy induced hair loss, and a steroid mouthwash to reduce targeted agent stomatitis. She is an investigator and the chair of the Safety Committee for the multicenter adaptively randomized phase II I-SPY2 trial, and also serves on the Novel Agents Committee. Dr. Rugo is the co-chair of the Triple Negative Working Group and an active member of the Translational Breast Cancer Research Consortium (TBCRC) and is the principal investigator of several TBCRC trials including a multi-center immunotherapy trial funded by the Breast Cancer Research Foundation (BCRF). She is an active member of the Alliance (formerly CALGB) Breast Committee, as well as ASCO, where she serves on the Guidelines Committee and as an editor for the Education Committee. In addition to her research, Dr. Rugo is an active clinician, and is committed to education, regularly lecturing locally, nationally, and internationally on subjects relating to the treatment of and supportive care for breast cancer. At UCSF, Dr. Rugo runs the Breast Forum, an open bimonthly evening educational session for breast cancer patients, families, and friends from throughout the bay area. Dr. Rugo graduated from the University of Pennsylvania School of Medicine in 1983. She completed a residency in internal medicine and primary care followed by a fellowship in hematology and oncology at the University of California San Francisco. She was a post-doctoral fellow in immunology participating in laboratory research at Stanford University from 1988-1990. In 1990, Dr. Rugo joined the faculty at UCSF in the Division of Hematology and Oncology. Dr. Rugo has been recognized for her excellence in both patient care and in teaching of both medical students and training physicians. She has received several awards including the Bank of America Giannini Foundation Award and a UCSF Clinical Cancer Center Investigator Research Program intra-mural award. In 2006, she was honored for her work in Breast Cancer Research by the Friends of the Breast Care Center. https://www.ourmbclife.org/episodes/we-remember-2022 monthly 0.5 2025-02-05 https://www.ourmbclife.org/episodes/dr-shanu-modi-how-to-get-a-standing-ovation monthly 0.5 2025-02-05 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/7425a68b-1acd-494c-829c-68b9f071f6eb/Shanu+Modi+1.jpg Episodes - Dr. Shanu Modi: How to Get a Standing Ovation at ASCO? - Shanu Modi, MD Growing up in a small farming community in rural Missouri, Stephanie Lynn Graff, MD, FACP was the first in her family to attend college. Because she was drawn to science from a young age, she enrolled in a 6-year medical program right out of high school. As she progressed from medical school to residency to a fellowship, she was fascinated by every aspect of the science of oncology—including cell biology and pharmacology. Dr. Stephanie Graff is the Director of Breast Oncology at Lifespan Cancer Institute at the Legorreta Cancer Center at Brown University in Providence, Rhode Island. Dr. Graff serves as co-lead of the Breast Cancer Translational Research Disease Working Group at Brown University and is an Assistant Professor of Medicine at the Warren-Alpert School of Medicine. Prior to joining the team at Lifespan/Brown, she was Director of both the Breast Program and Clinical Research at the Sarah Cannon Cancer Institute at HCA Midwest, as well as Associate Director of the Breast Cancer Research Program at Sarah Cannon Research Institute and National Breast Lead for the Sarah Cannon Cancer Network’s clinical programs. In addition, Dr. Graff serves as a medical advisor to the Dr. Susan Love Foundation for Breast Cancer Research. Dr. Graff is board certified in Medical Oncology, Hematology, and Internal Medicine; and completed a breast oncology sub-fellowship at the University of Kansas. Dr. Graff has broad experience as a Principal Investigator on numerous clinical trials across all phases of drug development, in addition to work in translational research, genomics, and gender bias. In addition to scientific publications, she is an award-winning writer, social media influencer, and sought-after public speaker. Dr. Graff has received the Frist Humanitarian Award for her work in the community and the Benjamin L. Sapers Memorial Award for her “passion for pedagogy, academic rigor, empathy and humanism, with profound feeling for the person as patient.” Dr. Graff currently serves on the American Cancer Society Rhode Island Leadership Council and actively volunteers in the American Society of Clinical Oncology, where she is a 2020 graduate of the prestigious ASCO Leadership Development Program, and now serves on the Joint Certifications Committee and Women In Oncology Work Group. Ultimately, Dr. Graff is passionate about connecting with her patients to provide personalized, comprehensive oncology care, advancing breast cancer research, and breast cancer prevention. https://www.ourmbclife.org/episodes/the-her2-low-show monthly 0.5 2025-02-05 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/bea7dade-a2ca-4bc5-9737-3d6ebed5767a/Dr+David+Hicks.jpg Episodes - MBC101: The HER2-Low Show - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/082ef94c-9b10-48fd-a56d-93c4c30da90d/Dr+Maryam+Lustberg+1.jpg Episodes - MBC101: The HER2-Low Show - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/954ac013-4a66-4a6d-8443-690e40701859/Natalia+Green+1.jpg Episodes - MBC101: The HER2-Low Show - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.ourmbclife.org/episodes/the-legacy-of-lisa-laudico monthly 0.5 2025-02-05 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/189b2332-dc64-4adf-a368-994bfa4c3385/Laudico+Headshot+August+2021.png Episodes - The Legacy of Lisa Laudico - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.ourmbclife.org/episodes/season-5-preview monthly 0.5 2023-03-17 https://www.ourmbclife.org/episodes/report-back-from-asco-20220 monthly 0.5 2025-02-04 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/08d1c85c-dd95-4fda-852b-957d6fb8fc16/Iyengar_2016.png Episodes - Report Back from ASCO 2022: What’s the Latest in MBC Research? - Neil Iyengar, MD Growing up in a small farming community in rural Missouri, Stephanie Lynn Graff, MD, FACP was the first in her family to attend college. Because she was drawn to science from a young age, she enrolled in a 6-year medical program right out of high school. As she progressed from medical school to residency to a fellowship, she was fascinated by every aspect of the science of oncology—including cell biology and pharmacology. Dr. Stephanie Graff is the Director of Breast Oncology at Lifespan Cancer Institute at the Legorreta Cancer Center at Brown University in Providence, Rhode Island. Dr. Graff serves as co-lead of the Breast Cancer Translational Research Disease Working Group at Brown University and is an Assistant Professor of Medicine at the Warren-Alpert School of Medicine. Prior to joining the team at Lifespan/Brown, she was Director of both the Breast Program and Clinical Research at the Sarah Cannon Cancer Institute at HCA Midwest, as well as Associate Director of the Breast Cancer Research Program at Sarah Cannon Research Institute and National Breast Lead for the Sarah Cannon Cancer Network’s clinical programs. In addition, Dr. Graff serves as a medical advisor to the Dr. Susan Love Foundation for Breast Cancer Research. Dr. Graff is board certified in Medical Oncology, Hematology, and Internal Medicine; and completed a breast oncology sub-fellowship at the University of Kansas. Dr. Graff has broad experience as a Principal Investigator on numerous clinical trials across all phases of drug development, in addition to work in translational research, genomics, and gender bias. In addition to scientific publications, she is an award-winning writer, social media influencer, and sought-after public speaker. Dr. Graff has received the Frist Humanitarian Award for her work in the community and the Benjamin L. Sapers Memorial Award for her “passion for pedagogy, academic rigor, empathy and humanism, with profound feeling for the person as patient.” Dr. Graff currently serves on the American Cancer Society Rhode Island Leadership Council and actively volunteers in the American Society of Clinical Oncology, where she is a 2020 graduate of the prestigious ASCO Leadership Development Program, and now serves on the Joint Certifications Committee and Women In Oncology Work Group. Ultimately, Dr. Graff is passionate about connecting with her patients to provide personalized, comprehensive oncology care, advancing breast cancer research, and breast cancer prevention. https://www.ourmbclife.org/episodes/psilocybin-assisted-therapy-legal-and-advocacy monthly 0.5 2025-10-08 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/e3b64946-a102-4dd3-ad56-5b7f54115f1c/Erinn_Head_Shot_3.jpeg Episodes - Psilocybin-assisted Therapy: One Patient vs. the DEA - Erinn Baldeschwiler Erinn Baldeschwiler is a Washington-based mother of two teenagers, aspiring writer, cancer patient, entheogen patient advocate, and a woman coming to terms with end-of-life realties. After a split from her husband and business partner in 2017, Baldeschwiler wholeheartedly embraced the challenges of becoming an empowered-independent-woman and positive role model for her children. In March 2020, believing the darkest of days were behind her and a bright new future lay ahead, Baldeschwiler was diagnosed with Stave IV triple negative metastatic breast cancer and a prognosis of 24 months to live. Rather than retreating into the darkness of low-self-worth and self-pity, she embraced this new challenge as an opportunity to dive deeper into the realm of self-reflection and self-awareness as a sacred rite of passage of personal and spiritual growth. Baldeschwiler has been the lead plaintiff in seeking psilocybin therapy under Federal and State Right-to-try laws (RTT) in AIMS vs. DEA ongoing litigation case. Invited by her palliative care practitioner, Dr. Sunil Aggarwal of AIMS Institute in Seattle, Baldeschwiler joined the effort with an intention to help move psychospiritual entheogen healing forward through her own care, especially when it comes to helping those seeking comfort and palliation and those who would like to transform the care of dis-eases like cancer. “It is an honor to be a part of this pioneering effort and incredibly fulfilling to help steer the direction in which healing modalities are practiced in modern Western medicine,” she shares. “I view entheogen medicine, including psilocybin, as a vital return to ancient-indigenous-healing practices of our ancestors. Practices focused on healing physical, mental, emotional and spiritual suffering - a return to wholeness and connectedness. Such practices fill a very large gap in modern palliative care. I hold so much admiration and appreciation for those committed to this effort. Together we are making huge positive strides, it’s humbling to be a part of it.” Growing up in a small farming community in rural Missouri, Stephanie Lynn Graff, MD, FACP was the first in her family to attend college. Because she was drawn to science from a young age, she enrolled in a 6-year medical program right out of high school. As she progressed from medical school to residency to a fellowship, she was fascinated by every aspect of the science of oncology—including cell biology and pharmacology. Dr. Stephanie Graff is the Director of Breast Oncology at Lifespan Cancer Institute at the Legorreta Cancer Center at Brown University in Providence, Rhode Island. Dr. Graff serves as co-lead of the Breast Cancer Translational Research Disease Working Group at Brown University and is an Assistant Professor of Medicine at the Warren-Alpert School of Medicine. Prior to joining the team at Lifespan/Brown, she was Director of both the Breast Program and Clinical Research at the Sarah Cannon Cancer Institute at HCA Midwest, as well as Associate Director of the Breast Cancer Research Program at Sarah Cannon Research Institute and National Breast Lead for the Sarah Cannon Cancer Network’s clinical programs. In addition, Dr. Graff serves as a medical advisor to the Dr. Susan Love Foundation for Breast Cancer Research. Dr. Graff is board certified in Medical Oncology, Hematology, and Internal Medicine; and completed a breast oncology sub-fellowship at the University of Kansas. Dr. Graff has broad experience as a Principal Investigator on numerous clinical trials across all phases of drug development, in addition to work in translational research, genomics, and gender bias. In addition to scientific publications, she is an award-winning writer, social media influencer, and sought-after public speaker. Dr. Graff has received the Frist Humanitarian Award for her work in the community and the Benjamin L. Sapers Memorial Award for her “passion for pedagogy, academic rigor, empathy and humanism, with profound feeling for the person as patient.” Dr. Graff currently serves on the American Cancer Society Rhode Island Leadership Council and actively volunteers in the American Society of Clinical Oncology, where she is a 2020 graduate of the prestigious ASCO Leadership Development Program, and now serves on the Joint Certifications Committee and Women In Oncology Work Group. Ultimately, Dr. Graff is passionate about connecting with her patients to provide personalized, comprehensive oncology care, advancing breast cancer research, and breast cancer prevention. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/39e4307d-2ec0-49cb-9e26-ceaff6e8f078/Kathryn+Tucker+Headshot.jpg Episodes - Psilocybin-assisted Therapy: One Patient vs. the DEA - Kathryn L. Tucker, J.D. Kathryn L. Tucker is Special Counsel at Emerge Law Group, where she Co-Chairs the Psychedelic Practice Group. Prior to joining Emerge, Tucker served as Executive Director of the End of Life Liberty Project (ELLP). Tucker founded the ELLP during her tenure as Executive Director of the Disability Rights Legal Center (DRLC), the nation’s oldest disability rights advocacy organization. Tucker served two decades as Director of Advocacy and Legal Affairs for Compassion & Choices, working to improve care and expand choice at the end of life. Prior to that, Ms. Tucker practiced law with Perkins Coie. She has held faculty appointments as Associate Professor of Law at Loyola Law School, Los Angeles, and as Adjunct Professor of Law at the University of Washington, Seattle University and Lewis & Clark Schools of Law, teaching in the areas of law, medicine and ethics, with a focus on the end of life. In April 2014, Professor Tucker was named a Fulbright Specialist by the U.S. Department of State’s Bureau of Educational and Cultural Affairs and the Institute of International Education’s Council for International Exchange of Scholars, to share her scholarship abroad. She served as a Fulbright Specialist with Faculty Appointments at the Universities of Auckland, Canterbury and Otago in 2015; in 2019 Tucker received another Fulbright Specialist Grant to teach at law schools in the United Kingdom. In 2018, the ELLP was a Visiting Sponsored Project of the UCSF/UC Hastings Consortium on Law, Science & Health Policy. Ms. Tucker served as lead counsel representing patients and physicians in two landmark federal cases decided by the United States Supreme Court, Washington v. Glucksberg and Vacco v. Quill, asserting that mentally competent terminally ill patients have a constitutional right to choose aid in dying. These cases are widely acknowledged to have prompted nationwide attention to improving care of the dying, and to have established a federal constitutional right to aggressive pain management. Tucker is lead counsel in the nation’s first litigation under the Right to Try Act, representing a palliative care physician and several cancer patients seeking to compel DEA to allow access to psilocybin therapy. AIMS et al v DEA. Also experienced and skillful in legislative advocacy, Ms. Tucker was involved in the development of, and successful campaigns to pass, the Washington Death with Dignity Act (2008), Vermont’s Patient Choice at the End of Life Act (2013), and Oregon’s Psilocybin Services Act (2020). Ms. Tucker is recognized as a national leader in spearheading creative and effective efforts to promote improved care for seriously ill and dying patients. She served as co-counsel in the first case in the nation to assert that failure to treat pain adequately constitutes elder abuse, which resulted in a finding of liability and a jury verdict award of $1.5 million to the patient’s family. She has been principal author of various state legislative measures to ensure physician education in pain management and provision of information to terminally ill patients about end-of-life care options. She also defends physicians facing adverse consequences for treating pain attentively and aggressively. Ms. Tucker is listed in the prestigious directory Who’s Who in American Law and was recognized as Lawyer of the Year, Runner-Up by the National Law Journal. She appears frequently on television and radio discussing end-of-life care, decision-making and physician-assisted dying. Media appearances include Crossfire, the PBS NewsHour, Larry King and CNN. Her work has been profiled in the National Law Journal, American Lawyer, Journal of the American Bar Association, Legal Times, and the magazines George, Vogue, Time, People and Health, among others. Professor Tucker is an invited speaker at educational programs on the subjects of improving care at the end of life, end-of-life decision-making, and aid in dying. She has presented to the American Bar Association, the Association of American Law Schools, the American Society of Law, Medicine and Ethics, the National Conference of State Legislatures, the National Academy of Elder Law Attorneys, the American Pain Society, the American Academy of Pain Management, the Federation of State Medical Boards, and the American College of Legal Medicine. https://www.ourmbclife.org/episodes/psilocybin-assisted-therapy-patients monthly 0.5 2025-10-08 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/f5f18f1b-1b72-4abb-9ea4-00e75e70a3ee/Maari+Singfield.jpeg Episodes - Psilocybin-assisted Therapy: Patient Experiences - Maari Singfield Maari recently completed her Master of Arts in Counselling Psychology from Yorkville University and received her Bachelor of Arts in Psychology from Saint Francis Xavier University in 2016. She has worked as a producer, project manager and communications officer in various tech start-ups and government departments. In 2019, Maari was diagnosed with breast cancer and has been battling it since. The diagnosis set her on a path of deep learning about a wide range of alternative therapies and taught her about the importance of self-advocacy in the healthcare system. Maari currently lives in Aylmer QC, with her fiance Jack and their dogs Bo and Fitz. Growing up in a small farming community in rural Missouri, Stephanie Lynn Graff, MD, FACP was the first in her family to attend college. Because she was drawn to science from a young age, she enrolled in a 6-year medical program right out of high school. As she progressed from medical school to residency to a fellowship, she was fascinated by every aspect of the science of oncology—including cell biology and pharmacology. Dr. Stephanie Graff is the Director of Breast Oncology at Lifespan Cancer Institute at the Legorreta Cancer Center at Brown University in Providence, Rhode Island. Dr. Graff serves as co-lead of the Breast Cancer Translational Research Disease Working Group at Brown University and is an Assistant Professor of Medicine at the Warren-Alpert School of Medicine. Prior to joining the team at Lifespan/Brown, she was Director of both the Breast Program and Clinical Research at the Sarah Cannon Cancer Institute at HCA Midwest, as well as Associate Director of the Breast Cancer Research Program at Sarah Cannon Research Institute and National Breast Lead for the Sarah Cannon Cancer Network’s clinical programs. In addition, Dr. Graff serves as a medical advisor to the Dr. Susan Love Foundation for Breast Cancer Research. Dr. Graff is board certified in Medical Oncology, Hematology, and Internal Medicine; and completed a breast oncology sub-fellowship at the University of Kansas. Dr. Graff has broad experience as a Principal Investigator on numerous clinical trials across all phases of drug development, in addition to work in translational research, genomics, and gender bias. In addition to scientific publications, she is an award-winning writer, social media influencer, and sought-after public speaker. Dr. Graff has received the Frist Humanitarian Award for her work in the community and the Benjamin L. Sapers Memorial Award for her “passion for pedagogy, academic rigor, empathy and humanism, with profound feeling for the person as patient.” Dr. Graff currently serves on the American Cancer Society Rhode Island Leadership Council and actively volunteers in the American Society of Clinical Oncology, where she is a 2020 graduate of the prestigious ASCO Leadership Development Program, and now serves on the Joint Certifications Committee and Women In Oncology Work Group. Ultimately, Dr. Graff is passionate about connecting with her patients to provide personalized, comprehensive oncology care, advancing breast cancer research, and breast cancer prevention. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/3238869d-24c6-4e55-8f25-5ce45b72747c/Erica+Rex+1.JPG Episodes - Psilocybin-assisted Therapy: Patient Experiences - Erica Rex Erica is an award-winning journalist, bringing her impressive 20+ years of medical and journalistic experience to the world of psychedelic medicine. She is deeply embedded in the field of psychedelic research, writing for prestigious publications such as Scientific American, The New York Times and Psychedelics Today on the re-emergence of psychedelic medicine. She converses regularly with the top researchers in the field in both Britain and the US. She regularly gives invited talks about her experience as a patient and thought leader on psychedelic medicine trials to professional conferences and federal agencies, such as the National Institutes of Health. She’s been interviewed on NPR, Sky News, and other news outlets. Her work lends a unique female perspective to the male-dominated field of psychedelic medicine, telling the story of psychedelic renaissance from two perspectives: patient/subject and highly accomplished science journalist. Erica’s portrait is by photojournalist Pete Kiehart. Calming a Turbulent Mind (Scientific American) The Power of Psychedelics (Scientific American) Could the Sonoran Desert Toad Cure Narcissism? (Psychedelics Today) Clinical Trials and Spontaneous Mystical Experiences (Psychedelics Today podcast) A Breast Cancer Patient’s Perspectives on the Uses of Psychedelics in Medicine *(Erica’s talk starts at 1:04:41 and lasts about 44 minutes) https://www.ourmbclife.org/episodes/psilocybin-assisted-therapy-science monthly 0.5 2025-10-08 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/6ea41b7e-7765-4033-9fdb-b3616747aa5c/Dr.+Dunlop+2.jpg Episodes - Healing our Distress: The Potential of Psilocybin-assisted Therapy - Boadie W. Dunlop, MD, MSCR Growing up in a small farming community in rural Missouri, Stephanie Lynn Graff, MD, FACP was the first in her family to attend college. Because she was drawn to science from a young age, she enrolled in a 6-year medical program right out of high school. As she progressed from medical school to residency to a fellowship, she was fascinated by every aspect of the science of oncology—including cell biology and pharmacology. Dr. Stephanie Graff is the Director of Breast Oncology at Lifespan Cancer Institute at the Legorreta Cancer Center at Brown University in Providence, Rhode Island. Dr. Graff serves as co-lead of the Breast Cancer Translational Research Disease Working Group at Brown University and is an Assistant Professor of Medicine at the Warren-Alpert School of Medicine. Prior to joining the team at Lifespan/Brown, she was Director of both the Breast Program and Clinical Research at the Sarah Cannon Cancer Institute at HCA Midwest, as well as Associate Director of the Breast Cancer Research Program at Sarah Cannon Research Institute and National Breast Lead for the Sarah Cannon Cancer Network’s clinical programs. In addition, Dr. Graff serves as a medical advisor to the Dr. Susan Love Foundation for Breast Cancer Research. Dr. Graff is board certified in Medical Oncology, Hematology, and Internal Medicine; and completed a breast oncology sub-fellowship at the University of Kansas. Dr. Graff has broad experience as a Principal Investigator on numerous clinical trials across all phases of drug development, in addition to work in translational research, genomics, and gender bias. In addition to scientific publications, she is an award-winning writer, social media influencer, and sought-after public speaker. Dr. Graff has received the Frist Humanitarian Award for her work in the community and the Benjamin L. Sapers Memorial Award for her “passion for pedagogy, academic rigor, empathy and humanism, with profound feeling for the person as patient.” Dr. Graff currently serves on the American Cancer Society Rhode Island Leadership Council and actively volunteers in the American Society of Clinical Oncology, where she is a 2020 graduate of the prestigious ASCO Leadership Development Program, and now serves on the Joint Certifications Committee and Women In Oncology Work Group. Ultimately, Dr. Graff is passionate about connecting with her patients to provide personalized, comprehensive oncology care, advancing breast cancer research, and breast cancer prevention. https://www.ourmbclife.org/episodes/mbc-amp-parenting-expert-panel monthly 0.5 2025-02-04 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/5f4a39a5-186d-416d-a0e6-9a479910edf6/Dr+Eliza+%28Leeza%29+Park+2.jpg Episodes - MBC & Parenting Expert Panel - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/fdea6c99-eb88-4134-92b2-58915f486741/Morgan+Livingstone+1.png Episodes - MBC & Parenting Expert Panel - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1654007520457-FPLUE22J55Q1CVD086WY/A+Celeste+4.jpg Episodes - MBC & Parenting Expert Panel https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1654007542447-QE4ETVISK1HHZ210IJKR/A+Celeste+1.jpg Episodes - MBC & Parenting Expert Panel https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1654007541905-EJTS0LCVRD0BLH87A5B4/A+Celeste+3.jpg Episodes - MBC & Parenting Expert Panel https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1654007541953-VN7UK1GFZN2I3QDELJ58/A+Celeste+2.jpg Episodes - MBC & Parenting Expert Panel https://www.ourmbclife.org/episodes/mbc-parenting-the-kids-are-alright monthly 0.5 2025-02-04 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1652893830891-IYY9AK2IK9D9XAE3VEOR/Rivers+Family+1.jpg Episodes - MBC & Parenting: The Kids Are Alright https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1652893831090-OFU4PEMGPIBD4OCZO776/Rivers+Family+2.jpg Episodes - MBC & Parenting: The Kids Are Alright https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1b7bac09-0855-4a85-84a8-12ece0161073/Deltra+Family.jpg Episodes - MBC & Parenting: The Kids Are Alright - Make it stand out Deltra James and Family https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/b443e361-5006-4cd0-a396-2c302b607730/Natalia+and+Rosie.jpg Episodes - MBC & Parenting: The Kids Are Alright - Make it stand out Natalia & Rosie Green https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/e449b3c9-049c-4768-87ed-3ac7f1e24caf/Lisa+Laudico+and+fam.jpg Episodes - MBC & Parenting: The Kids Are Alright - Make it stand out Alex, Lisa, and Matthias Laudico https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1652893724898-6X9NPJJXSXUC439B9U7R/Steph%2C+Sarah%2C+%26+Mom+Poland+1+%282%29.PNG Episodes - MBC & Parenting: The Kids Are Alright https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1652893731773-KYWMRO3OJ0YQOAC05D4Y/Steph%2C+Sarah%2C+%26+Mom+Poland+2+%282%29.PNG Episodes - MBC & Parenting: The Kids Are Alright https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1652893740203-VQNUA5Y741OUN53WDBU3/Steph+%26+Sarah+Poland+3+%282%29.PNG Episodes - MBC & Parenting: The Kids Are Alright https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1652893406481-1AS0CKT7PYSPTNFO3NHO/Vivian+Pham+and+Mom+3+%282%29.JPG Episodes - MBC & Parenting: The Kids Are Alright https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1652893414170-C7T08MNSJCAC8OMVJU12/Vivian+Pham+and+Mom+2.jpeg Episodes - MBC & Parenting: The Kids Are Alright https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1652893424742-RNNBAPR9869HCSC7Z8PS/Vivian+Pham+Kesem.png Episodes - MBC & Parenting: The Kids Are Alright https://www.ourmbclife.org/episodes/dr-nancy-lin-are-cns-mets-becoming-more-treatable monthly 0.5 2025-02-04 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/9c7648cd-5b28-47bb-a2fb-223a5dbbb135/csm_315_1651550681_844ce27348.jpg Episodes - Dr. Nancy Lin: Are CNS Mets Becoming More Treatable? What’s New with STOP-HER2? - Nancy U. Lin, MD Growing up in a small farming community in rural Missouri, Stephanie Lynn Graff, MD, FACP was the first in her family to attend college. Because she was drawn to science from a young age, she enrolled in a 6-year medical program right out of high school. As she progressed from medical school to residency to a fellowship, she was fascinated by every aspect of the science of oncology—including cell biology and pharmacology. Dr. Stephanie Graff is the Director of Breast Oncology at Lifespan Cancer Institute at the Legorreta Cancer Center at Brown University in Providence, Rhode Island. Dr. Graff serves as co-lead of the Breast Cancer Translational Research Disease Working Group at Brown University and is an Assistant Professor of Medicine at the Warren-Alpert School of Medicine. Prior to joining the team at Lifespan/Brown, she was Director of both the Breast Program and Clinical Research at the Sarah Cannon Cancer Institute at HCA Midwest, as well as Associate Director of the Breast Cancer Research Program at Sarah Cannon Research Institute and National Breast Lead for the Sarah Cannon Cancer Network’s clinical programs. In addition, Dr. Graff serves as a medical advisor to the Dr. Susan Love Foundation for Breast Cancer Research. Dr. Graff is board certified in Medical Oncology, Hematology, and Internal Medicine; and completed a breast oncology sub-fellowship at the University of Kansas. Dr. Graff has broad experience as a Principal Investigator on numerous clinical trials across all phases of drug development, in addition to work in translational research, genomics, and gender bias. In addition to scientific publications, she is an award-winning writer, social media influencer, and sought-after public speaker. Dr. Graff has received the Frist Humanitarian Award for her work in the community and the Benjamin L. Sapers Memorial Award for her “passion for pedagogy, academic rigor, empathy and humanism, with profound feeling for the person as patient.” Dr. Graff currently serves on the American Cancer Society Rhode Island Leadership Council and actively volunteers in the American Society of Clinical Oncology, where she is a 2020 graduate of the prestigious ASCO Leadership Development Program, and now serves on the Joint Certifications Committee and Women In Oncology Work Group. Ultimately, Dr. Graff is passionate about connecting with her patients to provide personalized, comprehensive oncology care, advancing breast cancer research, and breast cancer prevention. https://www.ourmbclife.org/episodes/mbc-amp-parenting-the-parents-are-hanging-in monthly 0.5 2025-02-04 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1651499316613-L6MTHUZJLX627XQ0A1JO/Laudico+Headshot+August+2021.png Episodes - MBC & Parenting: The Parents Are Hanging In https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1651510547211-9234NDHRX432SMR3P4B1/Natalia+Green+1.jpg Episodes - MBC & Parenting: The Parents Are Hanging In https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1651499316561-NBLUZUE9GJBDTJVCGXOG/Martha+Carlson+2.jpeg Episodes - MBC & Parenting: The Parents Are Hanging In https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1651501429349-08TUXBRC38J1JW4RGIL1/Ashley+Fernandez+1.jpeg Episodes - MBC & Parenting: The Parents Are Hanging In https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1651499320258-28ZW2BCPGKDO703F1K05/Lynda+Weatherby.PNG Episodes - MBC & Parenting: The Parents Are Hanging In https://www.ourmbclife.org/episodes/er-progression-and-resistance monthly 0.5 2025-02-04 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/ae383a15-1218-4433-ab72-0d8d3a05ad25/Jhaveri+photo+%5B5+1+2020%5D.jpg Episodes - ER Progression and Resistance: Causes, Consequences, and Hope - Komal Jhaveri, MD, FACP Growing up in a small farming community in rural Missouri, Stephanie Lynn Graff, MD, FACP was the first in her family to attend college. Because she was drawn to science from a young age, she enrolled in a 6-year medical program right out of high school. As she progressed from medical school to residency to a fellowship, she was fascinated by every aspect of the science of oncology—including cell biology and pharmacology. Dr. Stephanie Graff is the Director of Breast Oncology at Lifespan Cancer Institute at the Legorreta Cancer Center at Brown University in Providence, Rhode Island. Dr. Graff serves as co-lead of the Breast Cancer Translational Research Disease Working Group at Brown University and is an Assistant Professor of Medicine at the Warren-Alpert School of Medicine. Prior to joining the team at Lifespan/Brown, she was Director of both the Breast Program and Clinical Research at the Sarah Cannon Cancer Institute at HCA Midwest, as well as Associate Director of the Breast Cancer Research Program at Sarah Cannon Research Institute and National Breast Lead for the Sarah Cannon Cancer Network’s clinical programs. In addition, Dr. Graff serves as a medical advisor to the Dr. Susan Love Foundation for Breast Cancer Research. Dr. Graff is board certified in Medical Oncology, Hematology, and Internal Medicine; and completed a breast oncology sub-fellowship at the University of Kansas. Dr. Graff has broad experience as a Principal Investigator on numerous clinical trials across all phases of drug development, in addition to work in translational research, genomics, and gender bias. In addition to scientific publications, she is an award-winning writer, social media influencer, and sought-after public speaker. Dr. Graff has received the Frist Humanitarian Award for her work in the community and the Benjamin L. Sapers Memorial Award for her “passion for pedagogy, academic rigor, empathy and humanism, with profound feeling for the person as patient.” Dr. Graff currently serves on the American Cancer Society Rhode Island Leadership Council and actively volunteers in the American Society of Clinical Oncology, where she is a 2020 graduate of the prestigious ASCO Leadership Development Program, and now serves on the Joint Certifications Committee and Women In Oncology Work Group. Ultimately, Dr. Graff is passionate about connecting with her patients to provide personalized, comprehensive oncology care, advancing breast cancer research, and breast cancer prevention. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/e8306754-a164-4d65-8752-a873a502ebbb/Razavi+Photo.jpg Episodes - ER Progression and Resistance: Causes, Consequences, and Hope - Pedram Razavi, MD, PhD Dr. Razavi is a medical oncologist and a physician-scientist focused on personalized care in breast cancer at MSKCC. He is the Director of MSK Breast Molecular Tumor Board, Breast Liquid Biopsy Program and Translational Platform and Associate Director of MSK Biomarker Development Program. He obtained his medical degree from Tehran University of Medical Sciences. He has a PhD in cancer epidemiology with a focus on population genetics at the University of Southern California followed by a postdoctoral fellowship at Channing Laboratory in Boston. He did his internal medicine residency training at the University of Southern California and completed his medical oncology fellowship at Memorial Sloan Kettering Cancer Center where he was also a postdoctoral fellow at the Laboratory of Dr. Jose Baselga. He joined MSK faculty in 2016 as a breast oncologist. His research efforts have been focused on two major areas: 1) integrative clinicogenomic studies to guide hypothesis-based translational research in breast cancer, and 2) the development and validation of circulating tumor biomarkers such as circulating ctDNA, methylomes . He serves as the PI of multiple large-scale genomic studies in breast cancer to devise and optimize computational and analytical pipelines based on statistical methods and machine learning algorithms to identify the biomarkers of response and resistance to systemic therapy and to predict outcomes. These efforts have led to the identification of novel mechanisms of resistance to major targeted therapies modalities in breast cancer including endocrine therapy, CDK4/6 inhibitors and PI3K inhibitors and shed light on new potentially druggable genomic drivers of breast cancer. Twitter: @PedramRazaviMD https://www.ourmbclife.org/episodes/understanding-progression monthly 0.5 2025-02-04 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/f4cd790f-77b0-40ab-8523-9b3f0247b748/Dr.+Stephanie+Graff+2.jpg Episodes - Dr. Stephanie Graff: Understanding Progression - Stephanie Lynn Graff, MD, FACP Growing up in a small farming community in rural Missouri, Stephanie Lynn Graff, MD, FACP was the first in her family to attend college. Because she was drawn to science from a young age, she enrolled in a 6-year medical program right out of high school. As she progressed from medical school to residency to a fellowship, she was fascinated by every aspect of the science of oncology—including cell biology and pharmacology. Dr. Stephanie Graff is the Director of Breast Oncology at Lifespan Cancer Institute at the Legorreta Cancer Center at Brown University in Providence, Rhode Island. Dr. Graff serves as co-lead of the Breast Cancer Translational Research Disease Working Group at Brown University and is an Assistant Professor of Medicine at the Warren-Alpert School of Medicine. Prior to joining the team at Lifespan/Brown, she was Director of both the Breast Program and Clinical Research at the Sarah Cannon Cancer Institute at HCA Midwest, as well as Associate Director of the Breast Cancer Research Program at Sarah Cannon Research Institute and National Breast Lead for the Sarah Cannon Cancer Network’s clinical programs. In addition, Dr. Graff serves as a medical advisor to the Dr. Susan Love Foundation for Breast Cancer Research. Dr. Graff is board certified in Medical Oncology, Hematology, and Internal Medicine; and completed a breast oncology sub-fellowship at the University of Kansas. Dr. Graff has broad experience as a Principal Investigator on numerous clinical trials across all phases of drug development, in addition to work in translational research, genomics, and gender bias. In addition to scientific publications, she is an award-winning writer, social media influencer, and sought-after public speaker. Dr. Graff has received the Frist Humanitarian Award for her work in the community and the Benjamin L. Sapers Memorial Award for her “passion for pedagogy, academic rigor, empathy and humanism, with profound feeling for the person as patient.” Dr. Graff currently serves on the American Cancer Society Rhode Island Leadership Council and actively volunteers in the American Society of Clinical Oncology, where she is a 2020 graduate of the prestigious ASCO Leadership Development Program, and now serves on the Joint Certifications Committee and Women In Oncology Work Group. Ultimately, Dr. Graff is passionate about connecting with her patients to provide personalized, comprehensive oncology care, advancing breast cancer research, and breast cancer prevention. https://www.ourmbclife.org/episodes/grief-loss-faith monthly 0.5 2025-02-04 https://www.ourmbclife.org/episodes/hey-doc-what-are-you-saying-to-me monthly 0.5 2025-02-04 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/92024da5-b7f3-4853-987b-28e39730d91e/Dr+Lidia+Schapira+July+25+2018+High+Resolution+Proofs+Steven+Gregory+Photography-2327-1.jpg Episodes - Dr. Lidia Schapira: Hey Doc, What Are You Telling Me? - Make it stand out Dr. Lidia Schapira is Professor of Medicine at Stanford University School of Medicine and Director of Cancer Survivorship at the Stanford Cancer Institute. She graduated from Dartmouth Medical School and trained at the Beth Israel Hospital in Boston in internal medicine and completed a hematology and oncology fellowship at the Brigham and Women's Hospital followed by a research fellowship in Aging at Harvard Medical School. Dr. Schapira’s clinical focus is in the treatment of breast cancer and cancer survivors. Her research addresses cancer outcomes and experiences of young breast cancer survivors, the psychosocial impact of cancer, and interventions to improve quality of life and health outcomes for people living with and beyond cancer. She holds leadership roles in national and international societies (American Society of Clinical Oncology and Association of Supportive Care in Cancer) and serves as Editor-in-Chief of ASCO’s website for the public, Cancer.Net and Consultant Editor for Art of Oncology for the Journal of Clinical Oncology. Throughout multiple clinical, research, editorial and educational activities, Dr. Schapira has devoted her career to improving the experience and outcomes of patients and families with cancer and the education of cancer clinicians. https://www.ourmbclife.org/episodes/end-of-life-planning-1 monthly 0.5 2025-02-04 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/77dd5075-7272-4c12-9a89-b550580196ba/Nurse+Julie1.jpg Episodes - Doing End-Of-Life Right - Julie McFadden, BSN, RN Julie McFadden, BSN, RN, has been a nurse for 14 years. She is highly experienced in the Intensive Care Unit. But for the past 5 years she has focused her work on hospice and palliative care in California. Seeing the vast scale of TikTok’s ability to reach people, she decided to share her experiences and the information she has gathered about death and dying. It was her intention to challenge the idea that talking about death and addressing it head on is taboo. By educating people and disseminating some of her own experiences she hoped her videos would help people become more comfortable with talking about death. What Julie didn’t expect was to become a viral sensation seemingly overnight. It turns out people are very curious about the end stages of life and what happens when they die. In her original viral video, called The Rally, she discusses what many of her patients experience as they begin the process of nearing the end of life, experiences science can’t explain. Her popularity grew after an article in Newsweek discussed her videos and her unusual ability to educate people on the topic of death. After articles appeared in various other publications, Julie’s following has grown to over 500K on TikTok and over 40K, and growing, on Instagram. She continues to be passionate about normalizing death through her educational and inspiring videos on social media and hopes that people will begin to view death as a natural aspect of life, and to the extent possible, diminish the overwhelming fearfulness it generates. You can find her on TikTok and Instagram https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/215660e9-9473-4965-ba9b-3d7e1eb3835e/JAOB+back+cover+photo+by+Lori+Sparkman+4.jpg Episodes - Doing End-Of-Life Right - Jennifer O’Brien Jennifer O’Brien has helped thousands live and love more fully by recognizing that: at the end of life comes death; family caregiving is both the hardest job and the greatest honor most of us will ever face; and grief is abundant love with no place to go. She is the author of The Hospice Doctor’s Widow: A Journal, an art journal filled with beauty, practical insights, humor, and heart. The book has won a Nautilus silver award in the Death & Dying/Grief & Loss category, a Next Gen Indie Book gold for Relationships, an Independent Publishers (IPPY) bronze for Gift, and an International Impact Award for its Design. For more than 30 years she has been a practice management educator of physicians and served as CEO for two large medical practices. She authored 45 articles and made hundreds of presentations. She holds a bachelor’s degree from Boston University and a master’s degree in organization development from Loyola University –Chicago. She lives in Little Rock, Arkansas. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/4b2e6c47-05bc-4fa5-8965-4edc9482e11f/Copy+of+Cal+Cates+2.jpeg Episodes - Doing End-Of-Life Right - Cal Cates Cal Cates is an award-winning writer, published researcher, international speaker, and the founder and Executive Director of Healwell, a non-profit whose mission is to improve quality of life for people affected by acute, chronic, and serious illness. They have trained thousands of healthcare providers in skills of resilience, self-awareness, communication, and forgiveness. They have dedicated their career to advocacy in healthcare, massage therapy as social justice, and to revolutionizing education for healthcare providers. Cal has trained with Roshi Joan Halifax, Ram Dass, Frank Ostaseski, and other leaders in the field of contemplative care and has created curriculum and written for trade journals on topics ranging from end of life care to interdisciplinary education to racism and the endless ways that humans make it hard to live in successful, equitable harmony. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/55b20635-2553-4616-ac1c-7cedea4efffd/Sundari+Malcolm+2.png Episodes - Doing End-Of-Life Right - Sundari Malcolm Sundari Malcolm is the Director of BIPOC Wellbeing for The Dinner Party At 27, and after 7 years of being her Caregiver, Sundari lost her mother to Breast Cancer. At 31 years old, she lost her father to Brain Cancer. Since then, Sundari has dedicated her life to the support of those managing a diagnosis and the transformation that follows. Outside of her work as the Director of BIPOC Well- being for TDP, Sundari is a birth and death Doula. She is a Yoga and Meditation teacher and the founder of Soul Sundari Wellness. She is an expat to Germany and a recent publisher of the book Grief Gems! https://www.ourmbclife.org/episodes/glimpses-of-hope monthly 0.5 2025-02-04 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/06e0ec73-269d-456e-8dd5-5e857bf8b1d5/RTAC+-+Dr.+Priya+Kumthekar+.png Episodes - Dr. Priya Kumthekar: Glimpses of Hope for Leptomeningeal Metastases - Make it stand out Dr. Priya Kumthekar is a UCNS certified neuro-oncologist from Northwestern University dedicated to patient care and moving the field of brain tumor research forward primarily through her leadership on clinical trials. She is currently involved in and leads many clinical trials including being the overall principal investigator of five investigator initiated treatment trials as well as the site principal investigator (PI) of over a dozen additional collaborative brain tumor treatment trials. Dr. Kumthekar is the planned study chair/overall PI for a multicenter, international breast cancer leptomeningeal clinical trial. Dr. Kumthekar has also been actively involved in the NCI funded clinical trials for many years. Within the NCTN (National Clinical Trials Network) and serves in leadership roles, particularly with the Alliance for Clinical Trials (Alliance”) for several years. In 2016, Dr. Kumthekar was appointed as the national Executive Officer of Neuro-Oncology at the Alliance. In this role, she oversees the conception and development of clinical trials in these two areas from early phase through registration studies. Dr. Kumthekar has teamed with various scientists both at Northwestern and at other institutions with the goal of using translational research to advance the field. These partnerships allow for cutting edge scientific discoveries to be successfully brought to the clinic for brain tumor patients to benefit. https://www.ourmbclife.org/episodes/pauline-boss-grief-ambiguous-loss monthly 0.5 2025-02-04 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/d3274606-290d-49cf-9364-e47a89cf7ad0/Dr.+Boss+by+Stephan+Kistler+2.jpg Episodes - Ambiguous Loss & Dr. Pauline Boss - Pauline Boss, Ph.D. Pauline Boss, Ph.D., Professor Emeritus at the University of Minnesota, family therapist, is a Fellow in the American Psychological Association and the American Association for Marriage and Family Therapy, and a former president of the National Council on Family Relations. With her groundbreaking work in research and practice, Dr. Boss coined the term ambiguous loss in the 1970s and since then, developed and tested the theory of ambiguous loss, a guide for working with families of the missing, physically or psychologically. She summarized this research and clinical work in her widely acclaimed book, Ambiguous Loss: Learning to Live with Unresolved Grief (Harvard University Press, 2000). In addition to over 100 peer reviewed academic articles and chapters, her other books include Loss, Trauma, and Resilience: Therapeutic Work with Ambiguous Loss (W. W. Norton, 2006) and Loving Someone Who Has Dementia: How to Find Hope While Coping with Stress and Grief (Jossey-Bass, 2011). Her most recent book is The Myth of Closure: Ambiguous Loss in a Time of Pandemic and Change (W. W. Norton, 2022). Her work is known around the world wherever ambiguous losses occur, and thus her books are now available in 18 different languages. For more information about Dr. Boss, her writings, and the ambiguous loss online training program, see www.ambiguousloss.com. https://www.ourmbclife.org/episodes/timothy-pluard-the-future-of-mbc-care monthly 0.5 2025-02-04 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/736505d5-07e7-4ac3-a044-79ad12bdbbdf/Timothy+Pluard.jpg Episodes - Dr. Timothy Pluard: the Future of MBC Care is Already Here - Timothy Pluard, MD Timothy J. Pluard, MD, is medical director at Saint Luke’s Cancer Institute and the Paul Koontz Endowed Chair of Breast Disease at the University of Missouri- KC School of Medicine. Under his leadership, Saint Luke’s has launched two new signature centers, offering a level of cancer expertise not found within 450 miles of Kansas City. In 2016, Saint Luke’s Hospital launched its innovative Koontz Center for Advanced Breast Cancer, one of the few centers nationally, and the only in the Midwest, dedicated exclusively to the care of patients with metastatic breast cancer. In 2017, Dr. Pluard led the creation of Saint Luke’s Center for Precision Oncology, the only center within a 450-mile radius that brings together experts in clinical oncology, tumor genomics, and computational biology. This unique multidisciplinary team has the expertise to identify the exact genomic alteration causing a patient’s tumor, and find the best possible treatment—even if it has never been used on that kind of cancer before. Prior to joining Saint Luke’s, Dr. Pluard served as associate professor of medicine at Washington University in Saint Louis, and clinical director of the breast oncology program at Siteman Cancer Center, a National Cancer Institute designated Comprehensive Cancer Center. He has published extensively on new therapeutic approaches to breast cancer and the care of metastatic breast cancer patients. https://www.ourmbclife.org/episodes/lara-macgregor-decline-with-hope monthly 0.5 2025-02-04 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/c7424922-a3b4-43f2-a3e4-0cfc110735f2/Lara+Headshave.png Episodes - Lara MacGregor: How To Decline Well With Hope - Lara MacGregor Lara was first diagnosed with breast cancer in 2007 at the age of 30 and 7 months pregnant with her second son. A woman Lara had never met, but with whom she shared a mutual friend sent her a package. Inside were beautiful scarves she wore during cancer treatment and a note saying, “You can do this.” The scarves were both practical and inspiring, and knowing someone else had worn the scarves and faced cancer helped Lara believe she could do it, too. That gesture led Lara down the path of creating Hope Scarves in 2012, as a way to capture the stories of treatment and living with cancer. Today, Hope Scarves is a bustling office of volunteers and staff, sending over 100 scarves a week all around the world. Hope Scarves has sent over 20,000 scarves to every state and 30 countries, to people facing over 90 different types of cancer. After almost 7 years in remission, Lara faced cancer again. She was diagnosed with Stage IV Metastatic Breast Cancer in January 2014. Scarves and stories were encouraging, but they weren’t going to extend or one day save lives. So in 2016, Hope Scarves established a Metastatic Breast Cancer Research Fund. To date, $925,000 has been given to support MBC Research, all matched 1:1 by anonymous donors for a $1.85 million dollar impact. Lara started Hope Scarves to spread hope, which she held onto for 15 years. Lara passed away on January 18, 2022 at the age of 45. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/d5719e32-7495-4df8-8310-9cffbb0e0010/April+Stearns+with+Wildfire.jpg Episodes - Lara MacGregor: How To Decline Well With Hope - April Johnson Stearns April Stearns was diagnosed at 35 years old with Stage 3 breast cancer that she found while breastfeeding her daughter. Four years later, while struggling to “go back to normal” and find other women in similar circumstances, April launched Wildfire Magazine. Now she enjoys not only publishing the stories of those “too young for breast cancer,” she also finds pleasure in helping others heal through learning to write and share their stories. April lives with her family on the coast of central California. Wildfire Magazine & Writing Community is a multi-platform media company specifically designed with the young breast cancer survivor and fighter in mind. We provide a bi-monthly narrative magazine, weekly podcast, and small-group writing workshops. Our audience members are all diagnosed under the age of 50 – a growing population decades younger than the average breast cancer fighter with few age-appropriate resources available. Our belief is that experiencing the stories of others diagnosed young provides a much-needed community and support network for today’s young breast cancer survivors. We go further than that, though, and help them learn to tell their own stories to the survivors coming up behind them. This has the dramatic effect of turning a traumatic cancer experience into an empowering one! Learn more at wildfirecommunity.org. https://www.ourmbclife.org/episodes/black-history-health-equity monthly 0.5 2026-02-09 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/e37141bf-612e-4e8d-bb4f-abfcf3a432a3/Sheila+Johnson.jpg Episodes - Black History & Health Equity Every Month, Every Day - Sheila Johnson Sheila M. Johnson is a pioneering breast cancer advocate with a particular focus on the black community. She has overcome personal adversity to help support and educate her community about the risks of breast cancer and how to live a fulfilling life once a diagnosis is received. In 2009 at the age of 43, while active duty military with the United States Air Force, Sheila received her breast cancer diagnosis. She was diagnosed with Stage IV HER2+ invasive breast cancer. By the time she received her diagnosis, the cancer had already metastasized to her liver and ribs. Since then, she has undergone intensive treatments including a bilateral mastectomy and many rounds of very intensive chemotherapy. This wasn’t the first time that breast cancer had touched Sheila’s life, as her own beloved mother Grace died from metastatic breast cancer in 2004. Ever since then, Sheila has been determined to carry on her mother’s legacy and her own diagnosis simply strengthened her commitment to be the voice the black community needed. Sheila uses her voice to raise awareness about the racial disparities faced by black women throughout their breast cancer journey. Receiving a breast cancer diagnosis is devastating for anyone, and Sheila passionately believes that racial disparities should not have an impact on the standard of treatment that black women receive. Sheila has also taken part in a clinical trial, something that she feels is vitally important because African American women are under-represented in clinical trials. Ten years as a breast cancer survivor is testament to Sheila’s strength of will. And she takes strength and comfort from her faith, which has helped her to find a greater meaning in her journey. She draws inspiration from her favorite bible verse, Matthew 17:20 – a mustard seed of faith. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/a4e00f75-4347-4499-839b-59d018a3308d/Stephanie+Walker.jpg Episodes - Black History & Health Equity Every Month, Every Day - Stephanie Walker Stephanie Walker Diagnosed in July 2015 with de novo MBC. A Registered Nurse with close to 40 years of clinical practice and secondary teaching experience. Her experience has been pediatric and adult critical care working in level 1 trauma centers to critical access hospitals. The last 15 years of nursing was with End of Life/Hospice care. Only aware of MBC advocacy 3 years after diagnosis, she has pushed for rural equality, equity in breast cancer. She is a member of MBC Alliance (in which she is project lead on the BECOME initiative (Black Experience of Clinical Trial and Opportunities for Meaningful Engagement ), LBBC Helpline/HMV volunteer and Susan G. Komen volunteer. She is married and lives in Tarboro NC with husband John and rescue dog Rex, advocating for men and women in rural areas as my own for equal access to quality healthcare , treatment modalities, and resources keeps her busy . Research and Clinical Trials are extremely important. I want researchers to reach out to men and women with MBC to put a human face on their work. Realize that we are dying to live a longer quality of life. “I’m an open book so ask me.” I don’t want anyone to feel alone, isolated or defeated. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/344ea6e2-a200-4fd4-95d6-2b1de85bc6c1/Ricki+Emerald.jpg Episodes - Black History & Health Equity Every Month, Every Day - Make it stand out Ricki Farley As a Stage 3A Triple Negative Breast Cancer Survivor/Thriver, Ricki’s personal purpose, passion, mission, ministry and blessing is to bring focus, attention, research and action to eradicating Black Breast Cancer, and supporting and coaching what she calls her “Breasties” through their breast cancer experience. Ricki is an award-winning seasoned marketing veteran that has transformed her strategic acumen into breast cancer advocacy. Ricki co-founded and serves as CEO of TOUCH, The Black Breast Cancer Alliance to address Black Breast Cancer as a unique and special disease state, with the overall goal of reducing the mortality rate for Black women. Ricki founded and serves as co-host for “The Doctor Is In,” a weekly live web series on the BlackDoctor.org Facebook page that reaches over 3 million viewers. She is a founding member of #BlackDataMatters, in partnership with Breastcancer.org, Ciitizen, The Center for Health Care Innovation, Morehouse School of Medicine and Susan G. Komen Foundation to encourage and elevate the importance of Black Women participating in clinical trial research. In January 2022, she started the When We Tri(al) Movement to change the game on Black women participating in clinical trials to improve outcomes for Black women with breast cancer. Ricki serves on the Board of Trustees for the Triple Negative Breast Cancer Foundation where she chairs the marketing committee. She is a board member for the Center for Healthcare Innovation, a non-profit research and educational institute making healthcare more equitable. She avidly works with pharmaceutical companies to provide the patient voice for breast cancer awareness, action, therapy/drug development and advocacy. Ricki has two daughters, Amanda Brown Lierman, Executive Director of Supermajority, and Hayley Brown, 4th Grade Teacher at Kipp DC. She has 3 granddaughters, Belle, 4, Leia, 2 and Hart, 10 months, who remind her of her purpose every day. Ricki is a graduate of Dartmouth College and holds an MBA from Kellogg Graduate School of Management at Northwestern University. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/d88a2b24-9895-4d3a-ab0f-39678dd30d3c/Kellee+Southern.jpg Episodes - Black History & Health Equity Every Month, Every Day - Kellee Southern Kellee Southern’s journey as a breast cancer advocate began on her 45th birthday, December 27, 2012, the day she received her diagnosis. She credits that day as the one that taught her the true value of having God in her life, being surrounded by loving family and friends and embracing life – every moment, every day. Following her diagnosis, Kellee started her own social media breast cancer awareness campaign called “Touch the Tatas,” through which she reminds women (and men) to do a self-examination on the 27th day of every month. As part of the campaign, she also encourages her pink sisters, their families and others to be their own advocate for treatment and wellness. As a result of her campaign, Kellee has become a much sought-after speaker — sharing her story of survivorship and raising awareness. In 2013, Kellee and her team of supporters formed Team Butterfly to help raise funds for breast cancer research as part of the Susan G. Komen Race for the Cure. Her passion for spreading awareness led to an invitation to speak on the national stage in 2014 and to participate on the Susan G. Komen Advisory Council. Since diagnosis, Kellee has become very involved in several different Breast Cancer Groups. She serves as a Board Member at For 3 Sisters based in Olney, MD. She has advocated on Capitol Hill with NBBC and serves as a Komen Advocacy Ambassador. She has also been accepted as a participant in the Upcoming Project Lead Institute. Kellee’s greatest joy is being the wife to her devoted husband (Alvin), a mother to three wonderful children (Glenn, Joshua and Angelique), grandmother to precious grandson (Aiden) and daughter to a loving and supportive mother (Bonnie). By the grace of God, she has also been given the treasured title of breast cancer survivor. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/efc61e33-079b-4765-8b31-3a6fc703c116/Tawana+Davis.jpg Episodes - Black History & Health Equity Every Month, Every Day - Reverend Tawana Davis, PhD Reverend Tawana Davis, PhD is currently the Mobilizer (Senior Operations Officer) for the national non-profit Carrie’s TOUCH, a breast cancer research, support, and policy organization that focuses on humanizing Black women and their experience with breast cancer. Reverend Dr. Davis is the daughter of the late Edward Eugene Davis Jr. and the late Rose Lee Davis. Born and raised in Harlem, New York she was educated in the public school system, raised in the African Methodist Episcopal Church, and began her life of service in the beautiful shadows of her mom and dad. After attending St. John’s University, Tawana completed her last year of studies at State University of New York Empire State with a Bachelor of Science in Human Resources Management. Reverend Dr. Davis earned a certificate in Project Management from New York University and Human Resources (PHR) from Cornell University. Later, and she received a Master of Divinity at Turner Theological Seminary at the Interdenominational Theological Center in Atlanta, GA. Rev Dr. Davis earned a Master of Arts in Leadership and Change and her Doctorate of Philosophy in Leadership ad Change at Antioch University Graduate School of Leadership and Change. Reverend Dr. Davis is a Womanist, thought provoker, speaker, preacher, and community leader. She is a domestic violence survivor and is in active treatment for metastatic breast cancer survivor. She is an advocate and activist for both domestic violence and breast cancer awareness. Reverend Dr. Davis is the Co-Founder of Soul 2 Soul Sisters, a Black Woman led, faith-based, racial justice non-profit organization that centers Black lives and experiences. Established in 2015, Soul 2 Soul Sisters is leading and facilitating anti-racism work across the country through its signature program Facing Racism. Tawana is a contributor to the ground-breaking academic textbook “Race Work and Leadership: New Perspectives on the Black Experience.” She hosts a podcast called #tuesdayswithtawna on Fb Live, various Podcast platforms, and YouTube. Tawana is featured as the moderator and strategic planner for the award-winning Healing the Healers II 4-part series on Domestic Violence Awareness produced by Odyssey Impact and Transform Films. Get Out the Vote with Nuns on the Bus featured Reverend Dr. Davis as a guest speaker regarding the importance of the Black church and voting. Sojourner Magazine’s 2021 February issue featured Reverend Dr. Davis highlighting her work as a domestic violence survivor and advocate. Dr. Matthew Knowles Impact Podcast on April 5, 2021 featured Reverend Dr. Davis to discuss the Future of the Black Church. Tawana is a proud mother of master level two educators, a grandmother, and most of all a Justice activist for all! https://www.ourmbclife.org/episodes/report-back-from-2021-sabcs monthly 0.5 2025-02-04 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/fedd7d46-33b2-4c74-9255-c60bcd464a4d/Screen+Shot+2022-02-22+at+1.43.53+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out What I want to focus on today is the few main areas that we'll start with HER2+ disease, where for me, one of the biggest result was a trial called Destiny Breast 03 which looked at the new antibody, drug conjugate T-DXd compared to TDM-1 and show that this is substantially superior at a second/ third line setting. But there are also other new drugs coming through, as we speak. We’ll have to work out how we best integrate them into the patient pathways. In triple negative breast cancer we have more substantial data on the role of immune therapy in the first-line setting in a trial we have long waited for its final readout in terms of overall survival. It is called KEYNOTE-355, and it has now given us further evidence, that the incorporation of immune therapy in a first-line treatment setting substantially improves overall survival in the group of patients with PD-L1 positive tumors. We've also learned a little bit more about who the patients are, who might benefit from immunotherapy, which we are very happy to share with you. The second really exciting development in triple negative breast cancer, but we can also discuss later on how this will go to other subgroups as well, is the emergence of new antibody drug conjugates. So we'll talk a little bit about what an antibody drug conjugate is and how they work. Many of you are aware of Sacituzumab but also T-DXd alone or in combination with immune therapy. We've been seeing the emergence of a new subgroup. You've all heard of HER2 low disease. This is what I would call a therapeutic subgroup. And we'll explain a little bit where this comes from and what I hope to see in the next six to 12 months for this group of patients. For hormone driven, breast cancer ER+ disease we have seen really important data that provides further evidence that the incorporation of CDK4/6 inhibitors can improve, not just short-term outcome, but also long-term outcomes and substantially improve overall survival. Whether it's with aromatase inhibitors or fulvestrant. We are learning more and more what changes occur in tumors with resistance to CDK4/6 inhibitors. I've learned some interesting data about mutations in the cancer and how we can possibly tackle them therapeutically going forward. We have seen the first positive trial of a new group of drugs for hormone-driven breast cancer called SERDs or oral SERDs drugs. And again, that gives me a lot of hope, as we will use the data to move these drugs to earlier lines of treatment, where they will probably make more of a clinical benefit. (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/5e64e069-95d5-4a5b-913c-32eeafbbbf6c/Screen+Shot+2022-02-22+at+1.48.09+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out Now, if I may start with HER2+ breast cancer, and again, I have to apologize. This is very much from a European perspective. I know that we treat slightly differently on the different sides of the Atlantic. When it comes to metastatic disease recurrence in most countries in the world for many years now, the standard in the first line and the first treatment’s setting has been giving a chemotherapy group called taxanes in combination with two drugs that target HER2, which is the driver of these HER2+ breast cancers: trastuzumab and pertuzumab, In the second line setting normally it reverts to TDM-1 (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/abe026b1-1421-44c1-bb15-ec27d1c75d0e/Screen+Shot+2022-02-22+at+1.58.39+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out An interesting study was presented at ASCO a few months ago, slightly different strategy, because most patients with HER2+ breast cancer in Europe at least will initially be started on a chemotherapy with HER2 targeted therapy. But this study that was conducted in China, looked at either hormone therapy plus HER2 targeted therapy or chemotherapy plus HER2 targeted therapy in patients with HER2+ breast cancer, but also hormone receptor positive disease. And what was interesting to see, that it's obviously a milder strategy, giving hormone therapy rather than chemotherapy. And in this particular trial the results were very similar in terms of how long the cancer was controlled, which is what we describe as progression-free survival, but also how long patients are able to live with their disease. And that is an interesting result. We should use it to think about our strategies and do a little bit more work in the context of our current treatment standards. An interesting subgroup analyses show that patients, who have earlier disease recurrence from primary breast cancer treatment probably benefit from chemotherapy. On the other hand, the longer it takes before breast cancer comes back patients benefit from the combination of HER2 targeted therapy and hormone therapy, according to this trial. So certainly warrants further investigation (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1ee57f26-4d1e-4173-be79-efbe5391aac1/Screen+Shot+2022-02-22+at+2.04.24+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out When it comes to the second line setting, patients would routinely get in Europe TDM-1 as second line therapy. In this setting, on average this treatment gives patients benefit of around nine months. (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/d23124a3-402d-4b6d-b6c3-f74ddb868cc5/Screen+Shot+2022-02-22+at+2.07.01+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out Again, what I want to share with you is really how the treatment has changed over the last two or three years. One of the big changes is the introduction of Trastuzumab Deruxtecan, a new antibody drug conjugate that has substantially more activity with a progression-free survival of nearly 20 months. And I want to talk a little bit about what these antibody drug conjugates are in their structure. This antibody drug conjugate is supposed to target on a surface protein in cancer cells. And this antibody has, through linker protein, a very powerful chemotherapy drug glued to it. Most antibody drug conjugates are very similar in their biology. (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/4ec9c6d4-3ca4-4ed7-ae45-40d162c7fe5f/Screen+Shot+2022-02-22+at+2.10.07+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out What we are learning is that there are substantial differences between different ADCs. So we can't just say an ADC that targets HER2 are all the same. They can be massively different in terms of the antibody, in terms of how this drug is glued to the antibody drug conjugate and that will define whether that gets released somewhere in the periphery or the very target in the cancer tumor, but also in terms of the chemotherapy drug that is bound to the ADC. In the past it was thought, the was ADC works: it binds to the cancer cell then that gets internalized into the inside of the cell. The antibody gets broken down. The chemotherapy drug gets released and it can ultimately start killing cancer cells. What we've learned very recently is that many of these new ADCs (antibody drug conjugates) have an additional way of working. And this is what we call a bystander effect. Bystander effect means that the drug isn't just staying in this cell where it initially binds to, but it can also destroy and tackle some of the cancer cells that are immediately around there. And this happens through two mechanisms. The chemotherapy drug can get back out of the cell. Some of the drugs release toxic molecules just before they get taken up in the cancer cells. Now, if you look at this new drug T-DXd compared to the TDM-1, the standard in a second line setting, you can see why these drugs are different, more drug-to-antibody-ratio and different chemotherapy drug linked to it. But also most importantly, there's a substantial bystander effect. (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1c987f3c-e49a-4d24-a820-afad3e6982ee/Screen+Shot+2022-02-22+at+2.13.25+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out The data we were waiting for a long time. and which are in my opinion groundbreaking and really changed the way we treat breast cancer. are from the Destiny Breast 03 trial. This is a trial of patients with metastatic HER2+ breast cancer. Patients were allowed to have brain metastases as long as they had been treated. The patients were randomized between the old standard TDM-1 and the new drug T-DXd (Trastuzumab Deruxtecan). The trial was looking at how long we can ultimately control cancer, whether we can do this better with one or the other treatment. About 10% of patients had this treatment as the first treatment for metastatic disease. 40% as a second,and half of the patients as a third or subsequent line of therapy. The data were massively positive and are really changing the way we treat HER2+ breast cancer. (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/43301ea0-5fb3-4a37-bcb9-443a857935aa/Screen+Shot+2022-02-22+at+2.17.06+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out . If you look at the progression-free survival, the time the cancer was controlled with this treatment was doubling of the percentage of patients who had good disease control after a year. The median time that cancer was controlled was nearly four times higher, increasing the time that cancer was controlled from 7 months to 25 months. If you look at who are the patients who benefit from this therapy, you can see very easily see that everything seems to be confirming that T-DXD substantially better in all subgroups compared to TDM-1. (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/f2d8536b-e353-4f06-a491-af2eb4291d71/Screen+Shot+2022-02-22+at+2.19.45+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out And looking at long-term outcome, looking at overall survival, patients who received T-DXD seem to be doing substantially better. And if you look at a simple and almost old-fashioned end point of response rate looking at whether the cancer actually shrinks, we see the response rate are nearly 80% with T-DXD compared to 34% with TDM-1 and with twice as many patients achieving a complete response, where no cancer is visible, but most importantly, only 1% of patients had failure of the treatment right at the beginning compared to 18% with TDM-1. So really groundbreaking activity, that in my opinion makes this treatment a new standard of care in this set of patients. (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/a29c4697-df32-4007-8166-8f43e839bd31/Screen+Shot+2022-02-22+at+2.21.35+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out Among the clinical problems we often have in management of patients with HER2+ breast cancer is that some of the treatments don’t tackle possible brain involvement very well. And so one of the analysis of the T-DXD study was to look at the group of patients who had brain involvement and those patients did equally well compared to TDM-1 with T-DXd (Trastuzumab Deruxtecan) as the rest of the group. So we can clearly say this drug doesn't just work outside the brain. It also provides substantial benefit for patients with brain involvement, as you can also see from the response rates, which were twice as high with 64% compared to 33% with TDM-1. And those data compare very favorably with a second drug that has shown great promise in patients with brain involvement over the last two years, called Tucatinib. In HER2CLIMB study they offered Tucatinib to patients with brain metastases that were treated and stable, but also with brain metastases that were still active. Both groups of patients had had a clear benefit from the addition of Tucatinib to HER2 targeted therapy with similar benefits as we see for Trastuzumab Deruxtecan. So my conclusion here is, we have a new standard of care, but we also have now two very effective therapies that can help improve the control of brain involvement and outside the brain in patients with HER2+ breast cancer. (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/64bbe9ca-0b45-46d0-b42a-a3c7b2d6ba35/Screen+Shot+2022-02-22+at+2.24.59+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out One of the important questions always, what is the price to pay for patients in terms of side effects? And there are subtle differences between T-DXd and TDM-1. TDM-1 has a little bit more increase in liver function tests versus T-DXd, a little bit more nausea and diarrhea which we have to learn to manage. TDM-1 has more thrombocytopenia, TDXd more decrease of white cell levels. But ultimately these are all side effects we know how to manage. The one side effect we were a little bit more anxious about from the initial studies was something called pneumonitis. The pneumonitis rate was around 10% and it's still something we need to monitor patients very carefully. But with good management, most patients have mild side effects, well tolerated. I mentioned earlier that there are other ADCs( antibody drug conjugates) coming through. (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/f834b690-d0f4-4cd2-84a0-21269cb9568c/Screen+Shot+2022-02-22+at+2.28.25+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out For example, SYD985 which is not yet available, these are just clinical research data. The TULIP trial presented at the European conference in September-October time compared SYD985 with standard chemotherapy plus HER2 targeted therapy and patients with at least two lines of therapy. (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/d5def6f7-b5f0-4309-8993-796794ad28e2/Screen+Shot+2022-02-22+at+2.31.17+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out And this drug improves PFS, not yet improves overall survival, but clearly it gives us hope that there are other treatment options beyond T-DXd. (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1bf8f27c-1a80-49b1-814d-66b30953c988/Screen+Shot+2022-02-22+at+2.33.27+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out Prior to the Destiny Breast 03 data most patients with HER2+ cancer would have received Trastuzumab and Pertuzumab in combination with taxanes as a first treatment, when that cancer started growing they would have been switched to TDM-1 and then had a third treatment T-DXd. With the data I just shared with you this is now changing. Patients should now receive T-DXd much earlier as a second line therapy, but at the same time we need to see what we are doing after T-DXD. And one of the things we are working actively on in terms of research, is trying to understand - are those tumors after T-DXD still HER2 expressing? What's the mechanism of resistance to T-DXD which will allow us to tailor future strategies more effectively? Where are we going to head in the development with HER2+ breast cancer? And if I can just speculate where we may be in two or three years' time, the T-DXD drug is clearly at the moment one of the most effective drugs we have ever seen in this context. And there are studies now ongoing that explore this drug as first-line therapy. And if you look at the activity we've seen in the second-third line setting, it is in my opinion, fairly likely that this drug may be superior in terms of efficacy to our current standards in the first line setting. But we obviously need to wait for the trial results for that, but we will also have to assess with the different treatment strategies, what impact they have on the quality of life of patients, because treatment strategies have different side effect profiles. We'll need to see in real life, how those treatments affect patients (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/cc78a13e-6c48-4b8b-8ce9-c0d358f1ef7e/Screen+Shot+2022-02-22+at+2.35.11+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out We move on to triple negative breast cancer. Those tumors that neither have estrogen nor progesterone, so no hormone receptors and no HER2 receptors. When it comes to metastatic triple negative breast cancer, the shape and options changed over the last few years substantially and clearly improved what we could offer with the new standard of chemotherapy and immune therapy for patients with PD-L1 positive tumors. PARP inhibitors in patients with BRCA germline mutations and otherwise single agent chemotherapy. And then in the second or third line setting a new targeted option really coming through, that isSacituzumab, a new antibody drug conjugate that provides clear patient benefits in this situation. (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1db427f3-8edb-4f2b-95dc-bda30cfc17e8/Screen+Shot+2022-02-22+at+2.38.07+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out One of the challenges we've had with triple negative breast cancer, one of the reasons why progress probably took a little bit longer than, for example, in ER+ breast cancer is that it is a very heterogeneous disease. What does that mean? It's probably not one subtype of breast cancer, it's as we would say in England, a mixed bag of different subtypes of breast cancer that share one characteristic being that they don’t have hormone receptors and don't have HER2 receptors. So the different subtypes can be very, very different in their behavior, but also in response to different treatments. There have been many attempts to classify triple negative breast cancer based, for example, on gene expression profiling. And whilst this has been helpful for us to understand the differences in the biology of triple negative breast cancer, therapeutically it's not really helpful. And therefore in the future we will probably describe triple negative breast cancers, as an example, this is a patient whose tumor is PD-L1 positive with SP142 assay of IC 3%, CPS score of 15, BRCA germline mutation drop too high, HER2 low, an antigen receptor free. And that will allow the oncologist to work out what are the best treatment strategies and also in which sequence should we give these treatments to patients. (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/d0892dc3-9799-4aeb-8bde-b58673c9e77d/Screen+Shot+2022-02-22+at+2.41.24+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out And that will allow the oncologist to work out what are the best treatment strategies and also in which sequence should we give these treatments to patients. Now, the two areas that we have seen a lot of change in the last 12 months is immune therapy. We finally had survival data from the second big Phase 3 trial in this setting. Impassion 130 was the first , KEYNOTE 355 was the second. Very similar trials giving chemotherapy together with immune therapy as a first treatment to patients with metastatic triple negative breast cancer. And what we have previously learned is that the big subgroup of patients who have PD-L1 positive tumors benefit. We have now seen in both trials that the addition of immune therapy clearly extends substantially and in a meaningful way overall survival with both of those trials, but we've also seen that patients with PD-L1 negative tumors do not seem to benefit from this therapy. (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/ce0de5c1-b876-4eb5-bc84-3921636c0157/Screen+Shot+2022-02-22+at+2.44.16+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out There's an ongoing debate about those different PD-L1 tests. And I'm not going to go too much into detail because it can be confusing, but I just want to mention the 2 assays we use for triple negative breast cancer. One is called SP142, and the other 22C3. It comes down to looking at the right cutoffs. 22C3 with a cutoff of a 1% shows 80% are positive, but SP142 with cutoff of 1%, only 40% of patients are positive. And if you use a cutoff of 10 for the 22C3 assay again, only 40% are positive. And this seems to be the group of patients who benefit. So it comes down to the small print, but you get a PD-L1 assay to work out whether immune therapy is the right therapy for you or not. We've also done additional work in trying to identify possible other subgroups that may or may not benefit from immune therapy by looking at the immune phenotypes, looking at molecular phenotypes. And the bottom line is whatever subtype of triple negative breast cancer it is, there is always a group of patients who have PD-L1 positive tumors, and that is the best marker to select patients for treatment with immune checkpoint inhibitors. (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/7a65d78e-79d0-44cb-8f23-a63a4bb3613b/Screen+Shot+2022-02-22+at+2.48.21+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out We also starting to understand what drives resistance to immune therapy. One of the factors I want to highlight here is angiogenesis, and that's the formation of blood vessels driven by the cancer. The reason why I mentioned that is we have drugs that target these blood vessels. There was a very small study presented at ASCO this year. They gave a trifecta combination chemotherapy, immune therapy and anti-vascular drugs targeting these new blood vessels. The majority of patients had a substantial response to this therapy. This is not standard of care. This is not something we should do outside of trials, but this gives us hope that again, we can drive research in a different direction, hopefully improve the outcome of patients in this disease setting. (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/b70d820c-19c2-4ca1-83b7-df7ad74f4443/Screen+Shot+2022-02-22+at+3.06.47+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out The second big area where we are making progress is antibody drug conjugates. So you heard about the biology of these drugs in HER2+ breast cancer. The same principle is applied in triple negative breast cancer, but we use different surface molecules to anchor these ADCs. Many of those show early promise, some targeting something called Trop2 with a drug called Sacituzumabor or more recently Dato-DXd targeting HER2, targeting HER3 so there's a range of these new drugs coming through, which gives me a lot of hope and are likely to give patients more chances in the years to come The front runner here is clearly Sacituzumab, the drug that is already licensed and routinely used. (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/2b4d43c3-01b2-4f54-9818-b74bb6cbb300/Screen+Shot+2022-02-22+at+3.10.00+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out And this was based on the results of a trial that compared Sacituzumab with standard single agent chemotherapy in patients who had already had two lines of triple negative breast cancer, looking at progression-free survival and overall survival, the drugs substantially improved the progression-free survival. It almost doubled overall survival in this heavily pretreated group of patients where it was in the past very difficult to make treatments work, but where we see now survival time twice as long as before. And most importantly, and again, coming back to an old-fashioned end point objective response, when we saw seven times higher response rate with Sacituzumab compared to standard chemotherapy. Now, why is the response important? If patients have some, for example shortness of breath or cough because of lung involvement and if we just stabilize the cancer with the treatment and not make it shrink, the symptoms are not going to get better. So if you have a treatment that makes the cancer shrink in a third of patients compared to 5% of patients that clearly gives patients symptomatic benefit. And we saw this in the quality of life data that showed a clear improvement for patients who received the new treatment compared to standard chemotherapy. And that improvement was carried on even into the next line of therapy. We saw some interesting biomarker data. Can we select patients based on the expression of Trop2, which is the target of the ADC. And the short answer is that it's not necessary because even if Trop2 is very low. Cancer patients still do better with this drug compared to standard chemotherapy. (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/9a860bd6-9a00-47ea-bd1e-102328848353/Screen+Shot+2022-02-22+at+3.13.59+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out There's also a second drug being developed that targets the same target Trop2, and this drug is called Dato-DXd and it's exciting and uses the same backbone the same biology as T-DXD I spoke about earlier in HER2+ disease in a small study, early data. We see substantial activity again in patients with heavily pretreated, triple negative breast cancer. And there are two things that give me hope. The patients that have prior treatment Sacituzumab. So something that targets the same time. And we're still able to respond and patients who had prior treatment with a similar platform drug, which again, shows the patients can also still respond. And that tells us a lot about the mechanisms of resistance. It gives us hope that we can give some of those treatments sequentially with good patient benefit. I said it at the beginning of. (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/59998b72-f24e-4532-ab6e-2230fdeebcb4/Screen+Shot+2022-02-22+at+3.54.10+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out We also defining a new subtype of breast cancer called HER2 low disease. Now, going back in history 20 years ago, where we started really looking routinely on HER2+ breast cancer, the definition of HER2+ was based on how patients responded to trastuzumab therapy. Patients only benefited from trastuzumab if they had very high expression, which is called IHC three plus on a tumor biopsy. These patients would get a benefit from the trastuzumab therapy. Whereas the patients with low expression would not. Now with these new drugs like T-DXd, that has the bystander effect, every single cell does not need to have high HER2 expression. We see interestingly enough now also activity with HER2 targeted drugs even in patients with only low HER2 expression. And that's a huge group of patients, two thirds of patients with hormone receptor positive breast cancer or one third of patients with triple negative breast cancer. We will see patients with very, very low almost absent HER2 expression with some possible response to this therapy. We are eagerly awaiting the trial data in HER2 low patients. The Phase 3 data are expected to come in the next few months. And I think that will help us to identify again, a new therapeutic although not biological subtype, with HER2 low disease. It gives us new treatment that gave me a lot of hope for patients. (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/161af35e-a411-48dd-9ddf-c780a444e3cb/Screen+Shot+2022-02-22+at+6.47.32+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out Finally we are working on combining these new ADCs with immunotherapy. You've seen the data with immunotherapy. You see the data with ADCs, but if you put those two drugs together, we have data from a small study we presented at ASCO earlier this year in patients who had low HER2, so they had low HER2 expression and were predominantly PD-L1 negative where immune therapy normally doesn't really work and practically all patients had some shrinkage. Two-thirds of patients had substantial shrinkage of the cancer, which gives me a lot of hope and we will be pursuing this and other studies to hopefully bring this to patients as the standard therapy. The key question for us in research to address over the next few months, is looking at the role of immune therapy in patients who have already received immune therapy in an early disease setting, we will have to work on these antibody drug conjugates (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/ca45b51b-93a6-4d3c-9849-31a1c8c2ca91/Screen+Shot+2022-02-22+at+6.50.45+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out And we will get interesting data in the next 12 to 18 months on further data on DNA damage repair targeting drugs, PARP inhibitors, but also AKT inhibitors where another Phase 3 trial will read out in the next year. (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/b38e3c69-180a-4603-86d3-06f95749c273/Screen+Shot+2022-02-22+at+7.16.44+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out Let me come finally to hormone driven breast cancer. where we had an exciting five years in terms of having really improved outcomes of patients substantially, for example, with incorporation of CDK4/6 inhibitors into treatment options, which are now the standard treatment as a first-line setting, either with Aromatase Inhibitors or with fulvestrant in patients who have resistance to Aromatase Inhibitors. And the three areas where we had interesting data where one key question was “Can we achieve long-term improvement of outcomes, so increase overall survival benefit with CDK4/6 inhibitors. And the short answer is “Yes, we can”. (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/e21a0a6b-2714-4b8a-8507-6c4d421f1ce1/Screen+Shot+2022-02-22+at+7.19.45+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out And I will share the data with you. We have also been learning some of those emerging mechanisms of resistance to CDK4/6 inhibitors, which give us new treatment options, for example, targeting ESR1 mutations. Finally, we are looking strategies post-CDK4/6 inhibitors with oral SERDS being one of the groups of the drugs that get a lot of attention and give me hope going forward. If you look at the overall survival data first in patients whose tumors are already resistant to aromatase inhibitors, we have seen now consistently with a different CDK4/6 inhibitors in the different trials a clear improvement in overall survival. And if you look at the different subgroups of patients, where the patients get CDK4/6 inhibitors a little bit earlier or later, or have endocrine naive or hormond resistant disease, all patient groups seem to derive a very similar benefit. The only group of patients I want to single out, is patients in one of the studies, those patients who received chemotherapy for advanced breast cancer and then only received the CDK4/6 inhibitors afterwards. They didn't seem to have quite as much of a benefit as patients who did not have prior chemotherapy for advanced disease, whether this is just play of chance in this trial or really telling us something about our biology, we can't say at this point in time. But it clearly just emphasizes the point that patients with hormone receptor positive breast cancer should receive endocrine therapy as the first treatment, wherever possible. (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/30a9ec09-4f1c-477c-8042-4a5e53a85997/Screen+Shot+2022-02-22+at+7.29.01+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out The data we were eagerly awaiting were the overall survival data in patients who received CDK4/6 inhibitors in combination with Aromatase Inhibitor in an earlier line of therapy. And we received data of the Monaleesa trial at the European conference and in San Antonio showing very clearly that patients will live longer if they get CDK4/6 in combination with hormone therapy and the benefit increases a year by year, at a four or five, six year survival data were substantially improved with the additional CDK4/6 inhibitors. And all patients seem to benefit equally, even patients who had chemotherapy prior to this in the early disease setting will derive a benefit. (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/68ee373f-3233-459c-b834-dd9045a96894/Screen+Shot+2022-02-22+at+7.33.27+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out What about when patients receive CDK4/6 inhibitors, what do we know about resistance? One of the interesting studies looked at genetic changing in the cancer induced by CDK4/6 inhibitors. There are clearly differences in genetic changes prior to treatment with CDK4/6 inhibitors and after CDK4/6 inhibitor therapy. And the differences are predominantly two areas, where one is in the area called ESR1. And many of you have heard of ESR1 mutations. ESR1 is the chain that encodes the estrogen receptor, our treatment target, and you can see substantially more mutations occurring in patients who have been on CDK4/6 inhibitor. It's an induced mutation and we got new drugs that target these mutations called SERDs. These are hormone therapies that don’t just block estrogen receptor, but they basically destroy estrogen receptor. So it's not just taking fuel away from an engine, it’s blowing up the whole engine and taking it out of the equation. And that's why this is an important mechanism of resistance because we can use it therapeutically. The second area that's emerging is something on chromosome 12 where we see change in gene called MDM2. And again, we have inhibitors in preclinical models that may hopefully over time give us new strategies of the treatment (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/b44e38ca-e607-4b9e-a2a7-f5a4558cad37/Screen+Shot+2022-02-22+at+7.34.53+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out . A really interesting study by the French group in exactly the same setting. So this was a study where patients received hormone therapy Aromatase Inhibitors combined with CDK4/6 inhibitors. After that, the group monitored patients regularly with a liquid biopsy looking for possible emerging mutations. Genetic changes in the blood were targeting ESR1, and they looked at patients where these ESR1 were occurring, but where the cancer was still stable. The group was trying to answer a question if you could at that moment make switch in terms of the therapy, keeping CDK4/6 inhibitors, e.g. palbociclib, but changing the hormone therapy backbone away from AI (letrazole). To fulvestrant, which is another SERD compound that can remove this mutated receptor. The data I think are fantastic, are really exciting, really intriguing. We, by simply switching the hormone therapy before patients progress but if they already have this emerging ESR1 mutation, we could control the disease twice as long as we did before.And this isn't just down to giving the extra drug, it's down to using it at the right time when those mutations are emerging. (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/c4fe1e77-3d4a-4f87-8efc-ad76a367fd2a/Screen+Shot+2022-02-22+at+7.38.09+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out And there's a whole area at the moment, going into these new hormonal therapies. And these are called SERDs. As I mentioned before, they selectively destruct the estrogen receptor, but there are also other drugs SERM, SERCA, CERAN, PROTAC you will hear a lot about. They all share a few interesting characteristics that give me a lot of hope.One is their active after fullvestrant or active after CDK4/6 inhibitors, but most importantly, the work in patients in tumors with ESR1, but also without ESR1 mutations. And when we looked at some of the early data coming out, we saw encouraging activity with quite a few of those drugs. (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/9606884e-b5c3-44c5-9c9f-0a30380ec092/Screen+Shot+2022-02-22+at+7.40.34+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out The first Phase 3 data came out at San Antonio just over a month ago from the Emerald study with a drug called Elacestrant. And this is a drug that was used in patients who already had a couple of lines of hormone therapy and all patients had already progressed on prior CDK4/6 inhibitors. So this is a group of patients where hormone therapy was not easy to still provide a benefit, but what was important to see when Elacestrant, the new third compound was compared with aromatase inhibitors or Fulvestrant, it clearly improved the time cancer was controlled, especially in patient with ESR1 mutations. (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/41207368-28bc-4f99-b469-10228acc11f7/Screen+Shot+2022-02-22+at+7.43.52+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out So if I may summarize just briefly in HER2+ disease we have a new standard of care moving forward very rapidly, called T-DXd, a new antibody drug conjugate that showed superior efficacy compared to TDM-1 in terms of progression-free survival. We are looking into other new drugs SYD985 and Pyrotinib just to mention, for HER2+ positive in phase three trials, but we will have to work out over the months and years to come how best to incorporate them possibly into treatment strategies. In triple negative breast cancer, immune therapy is clearly standard of care in the first line setting in patients with PD-L1 positive tumors. Based now on the overall survival data from KEYNOTE355, we show substantial improvement with different chemotherapy backbones, and we're learning more and more, how best to select patients for immune therapy benefits that seem to work across different molecular and immune subtypes of triple negative breast cancer Antibody drug conjugates are for me for the next few years probably the most exciting developments. Sacituzumab is already standard of care in triple negative breast cancer for patients with at least two lines of therapy. T-DXd and Dato-DXd are emerging, even in triple negative breast cancer alone or in combination with immune therapy. We spoke about how HER2 low disease is an emerging therapeutic but not biological subtype of breast cancer. In ER+ breast cancer we finally have seen long-term survival improvement with CDK4/6 inhibitors in both sensitive and resistant disease. We are gradually understanding better the mutational profiles that are emerging in patients with resistance and can switch the endocrine backbone there. For example, in patients with ESR1 mutations to tailor therapies better, we are also seeing that oral SERD compounds are working. We have a proof of principle and we will have to work out over the next few years where best to use them. And I would expect them to move into earlier lines. So we have overall made a lot of progress that gives me hope. We're clearly not where we need to be. Where we need to be at some point is that we can cure routinely patients with metastatic breast cancer in all subtypes. And that's still not routinely possible, but we are making rapid progress with new treatments, with new groups of drugs that are more targeted that are better tolerance. And also improve long-term outcome of patients. I look forward to discussing these advances. (From the transcript, Professor Schmid) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/e82fceb3-e01f-4cba-8067-32c8208d5893/Screen+Shot+2022-02-22+at+7.48.35+PM.png Episodes - Report Back from SABCS 2021: What’s the Latest in MBC Research? - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.ourmbclife.org/episodes/mbc101-brain-mets-management monthly 0.5 2025-02-04 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/fa9b47c0-672e-4701-b5cf-b92402f6a18b/Screen+Shot+2022-01-20+at+9.39.14+PM.png Episodes - MBC101 - What Happens When MBC Spreads to the Brain? - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/95a5f9f9-66bf-427d-ba4c-a41f0ab4c779/Screen+Shot+2022-01-20+at+9.37.48+PM.png Episodes - MBC101 - What Happens When MBC Spreads to the Brain? - Make it stand out “A big shift toward SRS has taken place over the past decade, which largely has been driven by the results of several randomized trials, specifically those reported by Soffietti and colleagues, Aoyama and colleagues, and Chang and colleagues. In these trials, patients with up to 3 or 4 brain lesions underwent SRS either alone or in combination with whole-brain radiation. All of the studies showed that although the addition of whole-brain radiation delayed progression to the next central nervous system (CNS) event, overall survival did not improve, quality of life worsened, and neurocognitive problems developed. So for patients who present with a limited number of lesions that are small enough and in a location amenable to SRS, we use that approach in an attempt to minimize short- and long-term toxicity to the brain. Patients who present with multiple lesions, however, are still best served by whole-brain radiation.” (Dr. Nancy Lin Update on Managing Brain Metastases in Breast Cancer) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/f381cc9f-9b08-4158-8ac3-016a461b334f/Screen+Shot+2022-01-20+at+9.46.29+PM.png Episodes - MBC101 - What Happens When MBC Spreads to the Brain? - Make it stand out Ionizing radiation is a form of energy that acts by removing electrons from atoms and molecules of materials that include air, water, and living tissue. Ionizing radiation can travel unseen and pass through these materials. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/b215db68-722c-497f-90af-205998b95158/Screen+Shot+2022-01-20+at+7.04.31+PM.png Episodes - MBC101 - What Happens When MBC Spreads to the Brain? - Make it stand out “Not all breast cancers are the same, not all breast cancers are developed or found because of the same cancer markers. So we tend to divide them into different subtypes. And those subtypes are based on the three main receptors that we can find in breast cancers, which are the estrogen receptor, progesterone receptor and the HER2 receptor. So when either the estrogen or the progesterone is overexpressed in breast cancer, we call that hormone positive breast cancer. And what that means is that the breast cancer cells are feeding off of the hormones: estrogen, or progesterone. They use them as a food or fuel to live. The HER2 receptor acts differently when it's overexpressed, it just allows the breast cancer cells to grow rapidly. So the most common subtype of breast cancer in the U S is hormone positive/HER2 negative and represents about a 70% of those breast cancer cases. The other 30% is represented between the triple negative and the hormone positive. And there's also a different molecular subtyping, called Luminal A, Luminal B, basal-like, and HErR2-like. There is a lot of overlap, but it tells us mainly that for those hormone positives, there are ones that have a little bit better prognosis and responsiveness to hormonal treatments and other ones that are less responsive to hormonal treatments, but responsive to chemotherapy.” (Transcript, Dr. Soyano) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/b7b4371c-da4e-40af-a81b-9aa48d4ddaf2/Screen+Shot+2022-01-20+at+7.05.53+PM.png Episodes - MBC101 - What Happens When MBC Spreads to the Brain? - Make it stand out “We know that patients are living longer, and breast cancer is a second most common cancer in the U S in females after skin cancers, and we're detecting it earlier. The incidents of brain metastases seems to be going up as well. A meta analysis (a collection of other trials) that was published this year showed that the incidents of brain metastases following the diagnosis of metastatic breast cancer ranges are between 25 and 46%. So somewhere along the 20 to 40% of breast cancer patients that have metastases will develop metastases to the brain. We also know that the hormone HER2 negative was the most common subtype of breast cancer found in early state, but this is not true for breast cancer brain metastases. The most common ones are the HER2 positive and the triple negatives. And that represents a little bit over a third of those. And then only about 15% of the breast cancer brain metastases are hormone positive/HER2 negative. Hereat our institution we did a retrospective review of all the brain metastases that were found in our database of breast cancer, lung cancer, melanoma. We found that because there's no real screening national guidelines looking for brain metastases in breast cancer patients, the patients that had breast cancer were more likely to be younger with more advanced central nervous system disease, require whole brain radiation and have poor overall survival in general, compared to the lung cancer patients and the melanoma patients. So it's food for thought about modifying and trying to find these patients earlier so that their outcome can be improved in the future(Transcript, Dr. Soyano) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/62e52902-a183-4a37-b801-8911840eecab/Screen+Shot+2022-01-20+at+7.07.15+PM.png Episodes - MBC101 - What Happens When MBC Spreads to the Brain? - Make it stand out The most common subtype of breast cancer. It tends to be more indolent, and the patients tend to have a longer life expectancy. Common sites of metastases include the bones, lungs, and the liver. Initial treatment options include endocrine therapy, which we call hormone blockers plus or minus targeted therapy, which could be CDK4/6 inhibitors or mTOR inhibitors. These are inhibitors of particular areas of the cell cycle. So if we are inhibiting division of the cells, the cells get arrested, and they cannot further progress. (Transcript, Dr. Soyano) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/ad46a95d-39cb-471f-a0ca-5f39e8613c31/Screen+Shot+2022-01-21+at+12.46.16+PM.png Episodes - MBC101 - What Happens When MBC Spreads to the Brain? - Make it stand out Ww know that CDK4/6 inhibitors, especially Ibrance and Verzenio have shown some intracranial activity in small early phase trials. So it gives us an idea that this drugs potentially can penetrate that BBBB and help treat. the brain mets in combination with the local regional therapies. There was also a phase 2 trial of hormone positive metastatic patients with active brain metastases that showed a modest clinical benefit. It was a small trial, and even though they did not meet what their primary endpoint, it included a variety of patients with more advanced unresectable tumors, lepto mets, etc. But importantly, the blood study from the patients on this trial showed that there were adequate concentrations of the drug that suggests that there was a good penetrance of this drug. So that led us to study that here at Moffitt cancer center, Dr.Ahmed is the PI. So we have a Phase 1/2 study of stereotactic radiation or SRS in the management of patients that are HR+/HER2- with brain metastases. So this trial allows patients that are eligible for SRS. That have up to 15 brain meds. They will be getting Verzenio with radiation in the beginning continuing with Verzenio along and will be followed up by their response. This trial is recruiting at Moffitt. Additionally, at Emory University in Atlanta, there's a similar study using stereotactic radio surgery with any CDK4/6 inhibitor in treating this patient. So another investigator is looking at that same concept, hopefully we'll have more data so we can, , change practice for the future. (Transcript, Dr Soyano) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/966d83ce-0a58-4a6f-a26f-3bc730876b0c/Screen+Shot+2022-01-20+at+7.09.41+PM.png Episodes - MBC101 - What Happens When MBC Spreads to the Brain? - Make it stand out A different subtype of breast cancer is called triple negative. It lacks expression of estrogen, progesterone or the HER2 receptors, these cancers tend to be more aggressive and are associated with genetic mutations or predisposition, such as BRCA1/2 mutations among others. Patients are commonly treated with chemotherapy plus or minus a combination with immunotherapy. The most common site of metastasis are liver, lung, and brain. And because we treat these patients commonly with chemotherapy, we know from experience that some chemotherapy agents penetrate the blood brain barrier to some degree. (Transcript, Dr. Soyano) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/f86dde3a-317c-4f25-ac02-1e7d6c328ae4/Screen+Shot+2022-01-21+at+12.49.01+PM.png Episodes - MBC101 - What Happens When MBC Spreads to the Brain? - Make it stand out The first antibody drug conjugate (ADC) approved by the FDA last year in April. It's an antibody that goes in and targets a specific protein present in cancer cells. For this particular drug, the protein is called Trop2. And that antibody is linked to a small chemotherapy drug. That drug is called SN38, so when the medication is administered, it targets the Trop2 proteins in the breast cancer cells and delivers the chemotherapy SN 38 directly into the cells. And that inhibits the repair of DNA and leads to cell death. Approval was based on the results from a trial called the IMMU-132-01. There was another trial called the ASCENT 3 that showed that in some patients that had breast cancer brain metastases, there was an improvement in the progression free survival or the time to progression in patients that had stable brain metastasis from their tumors. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/15e0f851-b74c-4a06-971b-ed0e34995c8f/Screen+Shot+2022-01-21+at+12.51.31+PM.png Episodes - MBC101 - What Happens When MBC Spreads to the Brain? - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/caceb3df-9f0a-4410-b1fe-b2f8d15db09f/Screen+Shot+2022-01-21+at+12.52.56+PM.png Episodes - MBC101 - What Happens When MBC Spreads to the Brain? - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/17cb4f44-d242-45de-aa2f-9b68dc1b0a36/Screen+Shot+2022-01-21+at+12.55.36+PM.png Episodes - MBC101 - What Happens When MBC Spreads to the Brain? - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/94b7e709-b8e0-4cff-aee4-2ad07feb64cb/Screen+Shot+2022-01-20+at+7.16.10+PM.png Episodes - MBC101 - What Happens When MBC Spreads to the Brain? - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.ourmbclife.org/episodes/does-advocacy-matter-the-new-breat-cancer-brain-mets-website monthly 0.5 2025-02-04 https://www.ourmbclife.org/episodes/road-to-a-cure-dr-sarat-chanderlapaty-md-phd monthly 0.5 2025-02-04 https://www.ourmbclife.org/episodes/unite-for-her monthly 0.5 2025-02-04 https://www.ourmbclife.org/episodes/living-with-a-de-novo-mbc-diagnosis monthly 0.5 2025-02-04 https://www.ourmbclife.org/episodes/fatima-cardoso monthly 0.5 2025-02-04 https://www.ourmbclife.org/episodes/hope-rugs monthly 0.5 2025-02-04 https://www.ourmbclife.org/episodes/body-image-amp-diet-culture monthly 0.5 2025-02-04 https://www.ourmbclife.org/episodes/rtac-goff-perkins monthly 0.5 2025-02-04 https://www.ourmbclife.org/episodes/rtac-lin-parsons monthly 0.5 2025-02-04 https://www.ourmbclife.org/episodes/we-remember monthly 0.5 2025-02-04 https://www.ourmbclife.org/episodes/rtac-sara-hurvitz monthly 0.5 2025-02-04 https://www.ourmbclife.org/episodes/rtac-larry-norton monthly 0.5 2025-02-04 https://www.ourmbclife.org/episodes/trace-what-it-means-to-us monthly 0.5 2025-02-04 https://www.ourmbclife.org/episodes/mbc-around-the-world monthly 0.5 2025-02-04 https://www.ourmbclife.org/episodes/charlotte-trailblazers monthly 0.5 2025-02-04 https://www.ourmbclife.org/episodes/relationships monthly 0.5 2025-02-04 https://www.ourmbclife.org/episodes/dashofjoy monthly 0.5 2025-02-25 https://www.ourmbclife.org/episodes/shirleymertz monthly 0.5 2025-02-04 https://www.ourmbclife.org/episodes/reportbackfromasco2021 monthly 0.5 2025-02-04 https://www.ourmbclife.org/episodes/twistedpink-and-a-dash-of-joy monthly 0.5 2025-02-04 https://www.ourmbclife.org/episodes/mbc-and-lgbtq2s monthly 0.5 2025-02-04 https://www.ourmbclife.org/episodes/facing-mortality monthly 0.5 2025-02-04 https://www.ourmbclife.org/episodes/magicofpalliativecare-ourstories monthly 0.5 2025-11-19 https://www.ourmbclife.org/episodes/project-life-and-a-dash-of-joy monthly 0.5 2025-02-04 https://www.ourmbclife.org/episodes/magic-of-palliative-care monthly 0.5 2025-11-19 https://www.ourmbclife.org/episodes/becomeproject monthly 0.5 2025-02-04 https://www.ourmbclife.org/episodes/wildfirelivereadings monthly 0.5 2025-02-04 https://www.ourmbclife.org/episodes/healingpowerofwriting monthly 0.5 2025-02-04 https://www.ourmbclife.org/episodes/debbiewassermanschultz monthly 0.5 2025-02-04 https://www.ourmbclife.org/episodes/april-trailblazer-and-dash-of-joy monthly 0.5 2025-02-04 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1619929187169-C2G0A5BG5KBW0I4X4LW4/fullsizeoutput_afc.jpeg Episodes - April Trailblazer & Dash of Joy No one should face MBC alone. Whether you have a diagnosis yourself, or you're a friend, family member or caregiver of someone with a diagnosis, we're here to lend support, give information, share experiences, and to lift you up every time you need it. Research has proven that having the support we need during our most challenging times is paramount to honing coping skills and striving for wellness. 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monthly 0.5 https://www.ourmbclife.org/episodes/category/Patient+Advocates monthly 0.5 https://www.ourmbclife.org/episodes/category/Fitness+and+Exercise monthly 0.5 https://www.ourmbclife.org/episodes/category/AI+and+Big+Data monthly 0.5 https://www.ourmbclife.org/episodes/category/Biomarker+Testing monthly 0.5 https://www.ourmbclife.org/episodes/category/Diagnosis+and+Treatment monthly 0.5 https://www.ourmbclife.org/episodes/category/Faith monthly 0.5 https://www.ourmbclife.org/episodes/category/Clinical+Trials+Process monthly 0.5 https://www.ourmbclife.org/episodes/category/Difficult+Life+Choices monthly 0.5 https://www.ourmbclife.org/episodes/category/Working+with+MBC monthly 0.5 https://www.ourmbclife.org/episodes/category/MBC+Patients monthly 0.5 https://www.ourmbclife.org/episodes/category/MBC+Research+Funding monthly 0.5 https://www.ourmbclife.org/episodes/category/Difficult+to+Treat monthly 0.5 https://www.ourmbclife.org/episodes/category/Radiation+Therapy monthly 0.5 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https://www.ourmbclife.org/blog daily 0.75 2025-10-23 https://www.ourmbclife.org/blog/talesofvulnerability-k33s2-p7izT monthly 0.5 2023-08-22 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/b46c16ef-2896-413f-8101-cb746ba83383/Sandra-Moss-600.jpg Blog - I Have a Voice - Sandra Moss Sandra is a retired attorney who had served as a Deputy Attorney General of New Jersey representing the Division of Youth and Family Services. Sandy, as she is known to her friends, was first diagnosed with cancer at age 19. She has survived thyroid, parathyroid, and breast cancer. She is now living with MBC that has spread to her lungs and brain. She is a poet, a writer, an actress, and an active member of an MBC support group at SHARE. https://www.ourmbclife.org/blog/honoring-our-women-tf8y8 monthly 0.5 2025-03-05 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1604986164191-HTCKL3IQA8ARIUWT80RL/Adiba+pod+photo.png Blog - From the Podcast Vault: The Our MBC Life Book Club - Season 1 Episode 21: Interview with Author & MBC Advocate Adiba Barney Natalia Green spoke with the inspiring badass, MBC advocate, and author Adiba Barney. Adiba’s life has been worthy of a book for a while and we are grateful she has written: “When Life Hands You Cactuses, Make Margaritas”. Hear how Adiba navigated two early-stage breast cancer diagnosis at age 27 and then 30, then her MBC diagnosis at age 37. She talks about her 15-year quest to become a mother and her passion for “living life like there is no tomorrow and like [she’s] gonna live forever.” https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/e4785910-3155-43c1-85f8-8af93b0986ad/IMG_5680.jpg Blog - From the Podcast Vault: The Our MBC Life Book Club - Season 2 Episode 17: MBC & the LGBTQ2S+ Community This episode sheds light on the issues facing members of the LGBTQ2S+ community living with breast cancer and on social determinants of health and health inequities. In this episode Senior Producer Natalia Green speaks with Kimiko Tobimatsu, Canadian employment and human rights lawyer and author of graphic memoir Kimiko Does Cancer. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/d3274606-290d-49cf-9364-e47a89cf7ad0/Dr.+Boss+by+Stephan+Kistler+2.jpg Blog - From the Podcast Vault: The Our MBC Life Book Club - Season 4 Episode 3: Ambiguous Loss & Dr. Pauline Boss In this episode our founder Lisa Laudico speaks with leading social scientist, family therapist, professor, and writer Dr. Pauline Boss about all of her research and her latest book, The Myth of Closure: Ambiguous Loss in a Time of Pandemic & Change. Dr. Boss has extended the lens of her groundbreaking research to the world we live in today. This is another episode that has something for everyone – not just those of us living with MBC or a terminal diagnosis. https://www.ourmbclife.org/blog/lepton-diagnosis monthly 0.5 2023-07-15 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1688598582520-8FGT4SMTLCZXZZP89UK1/Screenshot+2023-07-05+at+2.30.42+PM.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1688598635133-H68UX812G9UCDHPPYK42/Screenshot+2023-07-05+at+2.31.05+PM.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1688606947958-2WWZKM62Q9Q5WGHCIEMH/2.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1688606972541-997N719KPV396YVXTQQ3/3.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1688606987559-5D0TIYW21LSL2FPL35AJ/4.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1688607005018-1QKJKO8CJUDNKUCBX8ZU/5.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1688607026047-558JWQXA151VI7I1MHF5/6.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1688607041395-1IL9ACDOVIJ60744FHP8/7.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1688607056370-4XSZF55ZH22ECVS7R7DZ/8.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1688607072369-UC6T3TTAZ11N05YAA2FF/9.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1688607085699-GMO7A7342G8CJTRSWTQX/10.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1688607107710-APNW14LZ3XYYOWB0QK06/11.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1688607122790-HQSFPAPRP6R6MD2VN855/12.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/93e0017a-0d91-4b73-bb45-7719b4fae810/Screenshot+2023-07-05+at+3.27.29+PM.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement - Make it stand out LMD is classified as Type I (definitive diagnosis with positive CSF cytology or biopsy) or Type II (suspected, from clinical findings and MRI only) https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/2bff5bd5-0308-4357-8b26-260b40764c4c/Screenshot+2023-07-05+at+3.42.40+PM.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement - Make it stand out For this reason, the drugs are frequently injected directly into the cerebrospinal fluid. This is referred to as intraventricular CSF, or intrathecal chemotherapy. Intrathecal chemotherapy was once administered via a spinal tap needle. Today, surgeons usually place an Ommaya reservoir (an intraventricular catheter system) under the scalp, with the catheter traveling into the cerebrospinal fluid. This reservoir is left in place for the duration of chemotherapy treatment. Evidence for Benefit of Intrathecal Therapy This small randomized study illustrates that intrathecal delivery of systemic treatment improves the PFS (the primary endpoint). In addition, a retrospective analysis of the cohort of 254 patients, collected from different sites, showed that patients with Type I LMD (definitive diagnosis, presence of tumor cells in the CSF) benefited from intrathecal treatment. This, however, was not the case for patients without tumor cells in the CSF. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/0021ad47-8523-4504-a6a3-95bed64c3c51/Screenshot+2023-07-05+at+3.50.25+PM.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/a053576f-6f0d-4b3d-bd97-c954014d123a/Screenshot+2023-07-05+at+3.56.47+PM.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/6d2c16c2-462a-415e-9d1b-08687646fd1f/Screenshot+2023-07-04+at+1.33.41+PM.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/812e77a5-99e6-471e-8b94-bb952ba892c8/Screenshot+2023-07-04+at+1.36.38+PM.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1689214605977-KAN83GCBXGMRVZRX3V1U/Screenshot+2023-07-12+at+10.05.44+PM.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1689214573619-HYYLNGN36TFIKJVUI2TX/Screenshot+2023-07-12+at+10.06.43+PM.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1689214503635-RN8BVD7SAZC6PH32NOC1/Screenshot+2023-07-12+at+10.07.46+PM.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1689214534258-XIPZ01KXIE9CPIE6SEYB/Screenshot+2023-07-12+at+10.07.32+PM.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1689214475321-WVWXZ9922NFN3JUF67U5/Screenshot+2023-07-12+at+10.08.01+PM.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1689214445552-U5L2XMIMI0OLXH83913R/Screenshot+2023-07-12+at+10.09.17+PM.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1689214421996-95DTO2JM37QL3FQ0YNCP/Screenshot+2023-07-12+at+10.10.26+PM.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/861f1f0c-9d44-4c11-b6ee-3399669d5da2/Screenshot+2023-07-04+at+1.38.57+PM.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/b3256bc8-c1d7-4746-9480-7431f3053269/Screenshot+2023-07-05+at+5.46.00+PM.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/6d5bfbf7-813c-41af-8ad2-fced2dab4c86/Screenshot+2023-07-05+at+5.47.34+PM.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1689213120602-8GFJJW4Y23C4O2XBPSPS/Screenshot+2023-07-12+at+8.35.56+PM.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement 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Leptomeningeal Disease Diagnosis - Words of Encouragement https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/6e641166-d551-4a82-99fd-ce7ce7619a29/Screenshot+2023-07-12+at+8.37.21+PM.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement - Make it stand out Acronyms used in this slide: pCSI is proton craniospinal irradiation, NSCLC non-small-cell lung cancer, TAE adverse effects to treatment. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/6fdf043f-5ccc-4e46-a1dd-4a4a64864429/Screenshot+2023-07-12+at+8.37.35+PM.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/d169714b-308a-4139-ba33-631b39f5547a/Screenshot+2023-07-12+at+8.38.37+PM.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/dbbb357f-1743-4c91-a609-beb0c877ed33/Screenshot+2023-07-12+at+8.40.29+PM.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/7fc416fa-01ca-4b5c-8eef-1491d0c16f27/Screenshot+2023-07-12+at+8.42.34+PM.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/bb095eda-7cb7-4576-8746-12e57f3eb309/Screenshot+2023-07-12+at+8.43.45+PM.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/a10522b7-c2f0-420d-a9c5-3c348402a103/Screenshot+2023-07-05+at+5.50.01+PM.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/249d52b7-eabf-4563-b93e-f66bad563edc/Screenshot+2023-07-05+at+5.51.02+PM.png Blog - Leptomeningeal Disease Diagnosis - Words of Encouragement - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.ourmbclife.org/blog/martha-carlson monthly 0.5 2023-04-15 https://images.squarespace-cdn.com/content/v1/5f088cd8677e1572701406ad/1681492789890-QRK3RK1QFAEDKXFB38UR/Martha+Carlson+1.jpeg Blog - Martha Carson is Thriving Together with MBC 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